The prevalence of depression, anxiety, and sleep disturbances in COVID‐19 patients: a meta‐analysis

Annals of the New York Academy of Sciences, Journal Year: 2020, Volume and Issue: 1486(1), P. 90 - 111

Published: Oct. 2, 2020

Abstract Evidence from previous coronavirus outbreaks has shown that infected patients are at risk for developing psychiatric and mental health disorders, such as depression, anxiety, sleep disturbances. To construct a comprehensive picture of the status in COVID‐19 patients, we conducted systematic review random‐effects meta‐analysis to assess prevalence disturbances this population. We searched MEDLINE, EMBASE, PubMed, Web Science, CINAHL, Wanfang Data, Wangfang Med Online, CNKI, CQVIP relevant articles, included 31 studies ( n = 5153) our analyses. found pooled depression was 45% (95% CI: 37–54%, I 2 96%), anxiety 47% 37–57%, 97%), sleeping 34% 19–50%, 98%). did not find any significant differences estimates between different genders; however, varied based on screening tools. More observational assessing wellness outpatients countries other than China needed further examine psychological implications infections.

Language: Английский

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The Efficacy of Computerized Cognitive Behavioral Therapy for Depressive and Anxiety Symptoms in Patients With COVID-19: Randomized Controlled Trial

Journal of Medical Internet Research, Journal Year: 2021, Volume and Issue: 23(5), P. e26883 - e26883

Published: April 26, 2021

Background The prevalence of depressive and anxiety symptoms in patients with COVID-19 is higher than usual. Previous studies have shown that there are drug-to-drug interactions between antiretroviral drugs antidepressants. Therefore, an effective safe treatment method was needed. Cognitive behavioral therapy (CBT) the first-line psychological clinical treatment. Computerized CBT (cCBT) proven to be alternative does not require face-to-face a therapist patient, which suited pandemic response. Objective This study aims evaluate efficacy cCBT program we developed improving among COVID-19. Methods We customized focused on COVID-19, then, assessed its effectiveness. Screening based depression or for who scored ≥7 Hamilton Depression Rating Scale (HAMD17) Anxiety (HAMA). A total 252 at five sites were randomized into two groups: + as usual (TAU; n=126) TAU without (n=126). group received intervention 1 week. primary measures HAMD17 HAMA scores. secondary outcome Self-Rating (SDS), (SAS), Athens Insomnia (AIS). Assessments carried out pre- postintervention. patients’ one centers again within month after postintervention assessment. Results displayed significantly decreased score HAMD17, HAMA, SDS, SAS, AIS compared (all P<.001). mixed-effects repeated model revealed significant improvement (HAMD17 SDS scores, both P<.001), (HAMA SAS insomnia (AIS score, P=.002) during follow-up periods group. Additionally, females (P=.14) those middle school education (P=.48) showed no differences when Conclusions findings this suggest nonpharmacological anxiety, depression, Further research warranted investigate long-term effects Trial Registration Chinese Clinical Registry ChiCTR2000030084; http://www.chictr.org.cn/showprojen.aspx?proj=49952

Language: Английский

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Neuropsychiatric Complications of COVID-19

Current Psychiatry Reports, Journal Year: 2021, Volume and Issue: 23(5)

Published: March 16, 2021

To describe the presentation, etiologies, and suggested management of post-acute COVID-19 neuropsychiatric symptoms.

Language: Английский

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The impact of inequality on mental health outcomes during the COVID-19 pandemic: A systematic review.

Canadian Psychology/Psychologie canadienne, Journal Year: 2021, Volume and Issue: 62(1), P. 101 - 126

Published: Feb. 1, 2021

Previous research on pandemics and emergencies has shown that such events often widen health inequalities in society have a greater impact socially disadvantaged groups.No review so far looked at the of inequality factors mental outcomes during novel coronavirus outbreak .The aim current was therefore to assess COVID-19.After registration PROSPERO, systematic conducted for papers published up 31 July 2020 using databases Google Scholar, PsycINFO, PubMed (MEDLINE), Web Science.The following were considered: education, income, employment, occupation, material social deprivation, age, immigrant status, sexual orientation, functional health, cultural/racial background, sex, gender, place residence.Out 1,931 references, 117 studies (300,061 participants) included.Female being younger financial insecurity, lack access clear messaging/information about pandemic, proximity large infection sites, having existing physical and/or psychological conditions, subjected abuse/stigma because one's identity as member an ethnic or marginalised group predicted inequalities.More is required how affects less studied vulnerable populations, ethnic, sexual, gender participants, well interact affect long term.Recommendations researchers, practitioners, public authorities mitigating adverse populations are outlined.

Language: Английский

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Brain correlates of depression, post-traumatic distress, and inflammatory biomarkers in COVID-19 survivors: A multimodal magnetic resonance imaging study

Brain Behavior & Immunity - Health, Journal Year: 2021, Volume and Issue: 18, P. 100387 - 100387

Published: Nov. 3, 2021

Psychiatric sequelae substantially contribute to the post-acute burden of disease associated with COVID-19, persisting months after clearance virus. Brain imaging shows white matter (WM) hypodensities/hyperintensities, and involvement grey (GM) in prefrontal, anterior cingulate (ACC) insular cortex COVID, but little is known about brain correlates persistent psychopathology. With a multimodal approach, we studied whole voxel-based morphometry, diffusion-tensor imaging, resting-state connectivity, correlate MRI measures depression post-traumatic distress (PTSD) 42 COVID-19 survivors without lesions, at 90.59 ​± ​54.66 days COVID. Systemic immune-inflammation index (SII) measured emergency department, which reflects immune response systemic inflammation based on peripheral lymphocyte, neutrophil, platelet counts, predicted worse self-rated PTSD, widespread lower diffusivity along main axis WM tracts, abnormal functional connectivity (FC) among resting state networks. Self-rated PTSD inversely correlated GM volumes ACC insula, axial diffusivity, FC. We observed overlapping associations between severity during acute structure function, survivors, thus warranting interest for further study syndrome. Beyond these findings support hypothesis that regional GM, microstructure, FC could mediate relationship medical illness its psychopathological sequelae, are agreement current perspectives structural underpinnings depressive

Language: Английский

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Psychological Symptoms in COVID-19 Patients: Insights into Pathophysiology and Risk Factors of Long COVID-19

Biology, Journal Year: 2022, Volume and Issue: 11(1), P. 61 - 61

Published: Jan. 2, 2022

There is growing evidence of studies associating COVID-19 survivors with increased mental health consequences. Mental implications related to a infection include both acute and long-term Here we discuss COVID-19-associated psychiatric sequelae, particularly anxiety, depression, post-traumatic stress disorder (PTSD), drawing parallels past coronavirus outbreaks. A literature search was completed across three databases, using keywords for relevant articles. The cause may directly correlate the through direct indirect mechanisms, but underlying etiology appears more complex multifactorial, involving environmental, psychological, biological factors. Although most risk factors prevalence rates vary various studies, being female gender having history disorders seem consistent. Several will be presented, demonstrating presenting higher consequences than general population. possible mechanisms by which severe respiratory syndrome 2 (SARS-CoV-2) enters brain, affecting central nervous system (CNS) causing these discussed, concerning SARS-CoV-2 entry via angiotensin-converting enzyme (ACE-2) receptors immune inflammatory signaling on neuropsychiatric disorders. Some therapeutic options also considered.

Language: Английский

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Network analysis of depressive and anxiety symptoms in adolescents during the later stage of the COVID-19 pandemic

Translational Psychiatry, Journal Year: 2022, Volume and Issue: 12(1)

Published: March 10, 2022

Network analysis is an effective approach for examining complex relationships between psychiatric symptoms. This study was designed to examine item-level depressive and anxiety symptoms using network in adolescent sample identified the most central within depressive-anxiety model. Depressive were assessed Patient Health Questionire-9 (PHQ-9) Generalized Anxiety Disorder Screener (GAD-7), respectively. The structure of characterized "Strength" "Bridge Strength" as centrality indices symptom network. stability tested a case-dropping bootstrap procedure. Finally, Comparison Test (NCT) conducted whether characteristics differed on basis gender, school grade residence. revealed that nodes PHQ2 ("Sad mood"), GAD6 ("Irritability"), GAD3 ("Worry too much"), PHQ6 ("Guilty") model adolescents. Additionally, bridge linking this ("Guilty"), PHQ9 ("Suicide ideation"). Gender, residence did not significantly affect structure. Central (e.g., Sad mood, Irritability, Worry much, Guilty) key Guilty, Suicide ideation) may be useful potential targets intervention among adolescents who are at risk or suffer from

Language: Английский

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The global prevalence of depression, anxiety, and sleep disorder among patients coping with Post COVID-19 syndrome (long COVID): a systematic review and meta-analysis

BMC Psychiatry, Journal Year: 2024, Volume and Issue: 24(1)

Published: Feb. 6, 2024

Post COVID-19 syndrome, also known as "Long COVID," is a complex and multifaceted condition that affects individuals who have recovered from SARS-CoV-2 infection. This systematic review meta-analysis aim to comprehensively assess the global prevalence of depression, anxiety, sleep disorder in coping with syndrome.

Language: Английский

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Updated guidance on the management of COVID-19: from an American Thoracic Society/European Respiratory Society coordinated International Task Force (29 July 2020)

European Respiratory Review, Journal Year: 2020, Volume and Issue: 29(157), P. 200287 - 200287

Published: Sept. 30, 2020

Coronavirus disease 2019 (COVID-19) is a caused by severe acute respiratory syndrome-coronavirus-2. Consensus suggestions can standardise care, thereby improving outcomes and facilitating future research.An International Task Force was composed agreement regarding courses of action measured using the Convergence Opinion on Recommendations Evidence (CORE) process. 70% necessary to make consensus suggestion.The made treat patients with COVID-19 pneumonia remdesivir dexamethasone but suggested against hydroxychloroquine except in context clinical trial; these are revisions prior resulting from interim publication several randomised trials. It also that venous thromboembolic event be treated therapeutic anticoagulant therapy for 3 months. The unable reach sufficient yield post-hospital care survivors. fell one vote shy suggesting routine screening depression, anxiety post-traumatic stress disorder.The addressed questions related pharmacotherapy survivors, yielding suggestions. Management options which there insufficient formulate suggestion represent research priorities.

Language: Английский

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A living systematic review of the psychological problems in people suffering from COVID-19

Journal of Affective Disorders, Journal Year: 2021, Volume and Issue: 292, P. 172 - 188

Published: June 2, 2021

Language: Английский

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