Omentin—General Overview of Its Role in Obesity, Metabolic Syndrome and Other Diseases; Problem of Current Research State

Biomedicines, Journal Year: 2025, Volume and Issue: 13(3), P. 632 - 632

Published: March 5, 2025

Background: Omentin (omentin-1, intelectin-1, ITLN-1) is an adipokine considered to be a novel substance. Many chronic, inflammatory, or civilization diseases are linked obesity, in which omentin plays significant role. Methods: MEDLINE and SCOPUS databases were searched using the keywords “omentin” “intelectin-1”. Then most recent articles providing new perspectives on matter important studies, revealed crucial insight, selected summarize current knowledge role of literature review. Results Conclusions: The valid this evident course metabolic syndrome. In cases, elevated expression correlated with better diseases, including: type 2 diabetes mellitus, polycystic ovary syndrome, rheumatoid arthritis, dysfunction-associated steatotic liver disease, Crohn’s ulcerative colitis, atherosclerosis, ischemic stroke, for some it can marker than currently used ones. However, results studies not completely one-sided. It was proven participate development asthma atopic dermatitis have different concentration dynamics various types tumors. All omentin’s effects properties make attractive subject research, considering still unexplored inflammation mechanisms, may play prevent osteoarthritis, hepatocirrhosis, atherosclerosis mouse models. above places among potential therapeutic products, only as biomarker. main problems research state lack standardization, causes many contradictions disagreements field.

Language: Английский

Effect of Stress on Hormone Levels in the Blood Serum of Rats with Alimentary Obesity

Pharmacophore, Journal Year: 2024, Volume and Issue: 15(3), P. 47 - 52

Published: Jan. 1, 2024

Language: Английский