Clinical characteristics, etiology, and treatment of young adult‐onset epilepsy: A 24‐year retrospective study

Epilepsia Open, Journal Year: 2024, Volume and Issue: 10(1), P. 298 - 306

Published: Dec. 30, 2024

To analyze the clinical characteristics, etiology, drug treatment, and related factors of patients with young adult-onset epilepsy. The study included epilepsy aged between 18 44 years aimed to characteristics in people their response antiseizure medication (ASM) over a 24-year period (February 1999 March 2023). A total 4227 experienced onset age. median age was 26 (interquartile range [IQR]: 21-33), duration from first seizure starting treatment 3 months (IQR: 1.0-6.0). Structural etiology most common cause epilepsy, accounting for 43.2% (1827/4227) cases, which head trauma history craniotomy accounted 64.9% (1186/1827). However, these two causes did not necessarily result prompt or poor control. Co-morbid cognitive decline more prevalent than headache anxiety/depression. Multifactorial regression analysis showed that associated control longer (odds ratio [OR] 1.85; 95% confidence interval [CI] 1.58-2.16; p < 0.001), electroencephalography (EEG) epileptic discharge (OR 1.37; CI 1.17-1.67; focal 1.69; 1.38-2.07; clusters 3.35; 2.70-4.15; 0.001). Initiating after seizures (OR, 1.18; 0.98-1.15; = .08) 6 0.84; 0.67-1.03; .09) worsen effectiveness. Young frequently caused by craniotomies. time follow-up indicate In this article, we observed mainly craniotomy; co-morbid common. initiation young-onset months, one-third prior but factor had no effect on

Language: Английский

Effect of a Designed Educational Protocol on Quality of Life among Patients with Epilepsy

Deleted Journal, Journal Year: 2023, Volume and Issue: 31(4), P. 12 - 35

Published: Nov. 1, 2023

Background: Epilepsy is a disabling neurological disorder worldwide, affecting quality of life, which imposes great burden on patients and their caregivers.Improving the life precisely one main objectives therapeutic education, are considered gold standard in delivery health care.Aim: To evaluate effect designed educational protocol among with epilepsy.Design: A quasi-experimental research design using one-group (pre-posttest) approach was used.Setting: The study conducted at inpatient department outpatient clinics affiliated to Mansoura Main University Hospital.Subjects: purposive sample 100 diagnosed epilepsy were selected.Tools: Four tools used for data collection: Tool I: Structured interview questionnaire, II: Knowledge assessment III: self-management scale, IV: Quality inventory-31(QOLIE-31) scale.Results: There high statistically significance difference total mean score knowledge, practices, pre post implementing studied (p<.001).There significant positive correlation between practices 3 6 months (p<.001& p=.006; p=0.022&p =0.041) respectively.Conclusion: proved that, there an improvement knowledge scores patients, consequently had life.Recommendation: should be planned continuous manner applied regular basis epilepsy.

Language: Английский