Clinical patterns in a neuroimaging-based predictive model of self-reported dissociation DOI Open Access
Juliann B. Purcell, Boyu Ren, Cori A. Palermo

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 28, 2025

Assessment of trauma-related dissociation has been historically challenging given its subjective nature and the lack provider education around this topic. Recent work identified a promising neural biomarker dissociation, representing significant step toward improved assessment identification dissociation. However, it is necessary to better understand clinical factors that may be associated with biomarker. Participants were 65 women histories childhood maltreatment, posttraumatic stress disorder (PTSD), varying levels (e.g., co-occurring dissociative identity disorder, DID). Data drawn from previously published model predicting Multidimensional Inventory Dissociation severe pathological scores on basis functional connectivity. Here, we conducted k-means cluster analysis explore patterns in results prediction model. We then investigated differences among clusters range clinically-relevant variables. The clustering four distinct groups. connectivity best predicted those at low (cluster 1, 82% PTSD) high 3, 86% DID) ends self-reported scale. Cluster 2 also largely included participants DID (67%), but predictive was less accurate for these individuals. Follow up analyses revealed reported lower self-state intrusions, type DID-specific compared 3. performance linked This suggests future signatures improve DID. present study aimed examine brain signature two groups individuals (DID) who differed These findings suggest underscore importance comprehensively evaluating symptoms. Dissociative symptoms are difficult assess because experience highly many providers do not receive training Objective, brain-based metrics supplement self-reports would invaluable enhancing treatment

Language: Английский

Neuroscience-based relational art therapy and deep brain reorienting in the treatment of dissociative identity disorder DOI Creative Commons
Anna Gerge, Gabriella Rudstam, Hans Peter Söndergaard

et al.

Frontiers in Psychology, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 28, 2025

Art therapy (AT) has been proposed as a treatment for post-traumatic conditions, potentially by providing somatic sensory input that can (i) enhance the client’s sense of self and embodiment, (ii) modulate arousal, (iii) aid in rethinking reframing traumatic memories. However, evidence supporting AT dissociative disorders remains limited. The theoretical basis efficacy is discussed relation to findings regarding traumatized person’s brain mindset, well its altered functional network connectivity. It crucial consider specific alterations networks associated with trauma, particularly those occurring deep regions, which include midbrain, brainstem, cerebellum. hypothesis suggests early or severe trauma impair brain’s higher regulatory functions, explained cascade theory. This theory explains how diverse activation patterns within midbrain’s periaqueductal gray (PAG) midbrain influence limbic system cortices, thereby modulating states being behavior. Phase-specific, resource-oriented, long-term complexly individuals benefit from novel insights neuroimaging studies inform therapeutic methods. illustrated clinical vignette client diagnosed identity disorder (DID), where reorienting (DBR) was combined relational AT. component hypothesized have facilitated grounding present moment enhanced access her neurophenomenological self. Moreover, changes may occurred at implicit non-verbal levels. DBR believed helped remain previously avoided unbearable internal experience. To validate these assumptions, second author conducted semi-structured interview focused on experiences psychotherapy , including effect when introduced after were articulated through thematic analysis interview, yielded following themes: Loneliness, getting help moving towards togetherness . Further research development methods neuroplasticity necessary highly clients change heal are recommended.

Language: Английский

Citations

0

Clinical patterns in a neuroimaging-based predictive model of self-reported dissociation DOI Open Access
Juliann B. Purcell, Boyu Ren, Cori A. Palermo

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 28, 2025

Assessment of trauma-related dissociation has been historically challenging given its subjective nature and the lack provider education around this topic. Recent work identified a promising neural biomarker dissociation, representing significant step toward improved assessment identification dissociation. However, it is necessary to better understand clinical factors that may be associated with biomarker. Participants were 65 women histories childhood maltreatment, posttraumatic stress disorder (PTSD), varying levels (e.g., co-occurring dissociative identity disorder, DID). Data drawn from previously published model predicting Multidimensional Inventory Dissociation severe pathological scores on basis functional connectivity. Here, we conducted k-means cluster analysis explore patterns in results prediction model. We then investigated differences among clusters range clinically-relevant variables. The clustering four distinct groups. connectivity best predicted those at low (cluster 1, 82% PTSD) high 3, 86% DID) ends self-reported scale. Cluster 2 also largely included participants DID (67%), but predictive was less accurate for these individuals. Follow up analyses revealed reported lower self-state intrusions, type DID-specific compared 3. performance linked This suggests future signatures improve DID. present study aimed examine brain signature two groups individuals (DID) who differed These findings suggest underscore importance comprehensively evaluating symptoms. Dissociative symptoms are difficult assess because experience highly many providers do not receive training Objective, brain-based metrics supplement self-reports would invaluable enhancing treatment

Language: Английский

Citations

0