Cardiovascular disease and bipolar disorder: A review of pathophysiology and treatment implications
Mayuresh Chaudhari,
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Luis Méndez,
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Rene L. Olvera
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et al.
The International Journal of Psychiatry in Medicine,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 23, 2025
Objective
Despite
the
well-established
increased
risk
of
cardiovascular
mortality
in
individuals
with
bipolar
disorder
(BD),
prevention
and
treatment
factors
diseases
have
been
largely
overlooked
this
population.
This
manuscript
reviews
pathophysiological
basis
connection
between
BD
diseases,
highlighting
their
shared
mechanisms,
reciprocal
interactions,
relevant
strategies.
Methods
For
narrative
review,
a
search
was
carried
out
on
PubMed
using
keywords
disorder,
factors.
Results
The
frequency
morbidity
can
be
attributed
to
overlapping
biological
psychosocial
mechanisms.
These
mechanisms
are
complex
involve
both
direct
effects
indirect
mediated
by
lifestyle
pharmacological
Cardiovascular
also
significantly
exacerbate
clinical
course
increase
healthcare
costs;
thus,
effective
management
improve
psychiatric
outcomes
vice
versa.
However,
patients
frequently
encounter
barriers.
Conclusion
Awareness
initiatives
research
integrated
care
needed
determine
best
strategies
for
improving
BD.
Language: Английский
Global research trends in the intestinal microflora and depression: bibliometrics and visual analysis
Qian Xu,
No information about this author
Qingwei Xiang,
No information about this author
Zihu Tan
No information about this author
et al.
Frontiers in Cellular and Infection Microbiology,
Journal Year:
2025,
Volume and Issue:
15
Published: Feb. 25, 2025
In
recent
years,
the
relationship
between
gut
microbiota
and
human
health
has
garnered
significant
attention.
Notably,
potential
connection
mental
issues,
such
as
depression
anxiety,
emerged
a
new
focal
point
for
research.
While
some
studies
suggest
possible
link
these
factors,
field
remains
in
its
early
stages
of
development,
there
are
notable
methodological
sample
size
limitations.
This
study
aims
to
systematically
summarize
knowledge
systems,
research
hotspots,
development
trends
related
intestinal
microflora
within
context
conducted
search
publications
Web
Science
Core
Collection
(WOSCC)
prior
August
6,
2024.
The
selected
literature
was
subsequently
analyzed
using
VOSviewer
(v.1.6.20),
SCImago
Graphica
(v.1.0.39),
CiteSpace
(v.6.3.1).
encompassed
total
1,046
publications,
demonstrating
consistent
increase
annual
publication
volume.
primary
countries
identified
China
United
States,
with
contributions
from
institutions
University
California
College
Cork,
among
others.
Keywords
analysis
highlighted
high-frequency
terms
including
"gut
microbiota,"
"depression,"
"anxiety,"
revealed
10
keyword
clusters
along
20
strongest
citation
bursts
keywords.
focus
shifted
compositional
role
pathogenesis
depression.
Research
on
is
growing,
but
still
need
greater
collaboration
authors
across
regions,
more
ongoing
interaction
communication
further
explore
mechanisms
action
microbiota,
develop
microbiota-based
interventions,
facilitate
translation
findings
into
clinical
practice.
Language: Английский