Biological and computational assessments of thiazole derivative-reinforced bile salt enriched nano carriers: a new gate in targeting SARS-CoV-2 spike protein

RSC Advances, Journal Year: 2024, Volume and Issue: 14(52), P. 38778 - 38795

Published: Jan. 1, 2024

There is merit in investigating novel therapeutic molecules that hit vital targets during the viral infection cycle

Language: Английский

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Functionalized nanostructures and targeted delivery systems with a focus on plant-derived natural agents for COVID-19 therapy: A review and outlook

Nanotechnology Reviews, Journal Year: 2024, Volume and Issue: 13(1)

Published: Jan. 1, 2024

Abstract The COVID-19 pandemic strongly stimulated research on anti-SARS-CoV-2 virus treatments. present study reviews a nanotechnology approach to this task, i.e. , in other terms, nanomedicine approach. Nanotechnology aims create nanostructures or nanoparticles, also called nanoformulations, for targeted delivery of drugs, as well improved drug release control. This is particularly promising enhance the antiviral effect natural pro-drugs. Here, we review several nanoformulations developed medications against SARS-CoV-2. We draw special attention repurposing strategies known and therapies. Also, functionalized nanoparticles with specific targeting moieties functional groups were discussed. summary could motivate researchers pursue more studies exciting area by seeking nanotechnology-based, cutting-edge, tailored SARS-CoV-2 virus.

Language: Английский

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Nirmatrelvir, SIM0417, and RAY1216: potent and selective SARS-CoV-2 main protease inhibitors for the potential treatment of COVID-19

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 351 - 356

Published: Nov. 1, 2024

Language: Английский

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ORF6, a repressor of the MHC class I pathway: new molecular target for SARS-CoV-2 drug discovery?

Expert Opinion on Therapeutic Targets, Journal Year: 2023, Volume and Issue: 27(8), P. 639 - 644

Published: Aug. 3, 2023

Language: Английский

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