Current Obstetrics and Gynecology Reports, Journal Year: 2023, Volume and Issue: 12(3), P. 165 - 172
Published: Aug. 28, 2023
Language: Английский
JAMA Network Open, Journal Year: 2022, Volume and Issue: 5(6), P. e2219133 - e2219133
Published: June 28, 2022
Language: Английский
Citations
66
JAMA Pediatrics, Journal Year: 2022, Volume and Issue: 176(11), P. 1098 - 1098
Published: Oct. 3, 2022
The risk and benefits of COVID-19 vaccination during pregnancy are under investigation. Pooled evidence regarding neonatal maternal outcomes in association with is scarce.
Language: Английский
Citations
43
Frontiers in Pediatrics, Journal Year: 2025, Volume and Issue: 12
Published: March 27, 2025
With the global rise in preterm birth rates, bronchopulmonary dysplasia (BPD) continues to be a significant problem, affecting morbidity and mortality surviving infants. Preterm infants are particularly susceptible oxidative stress induced by sudden increases oxygen concentration, which plays crucial role pathogenesis of BPD. Herein, we addressed pathophysiologic mechanisms, clinical treatment, predictive biomarkers BPD from an perspective. We first review importance point out that sustained exposure hyperoxia exacerbates susceptibility immature lung free radicals. The antioxidant properties therapies for then summarized. Subsequently, based on lipid, protein, DNA damage obtained most comprehensive, accurate, representative biomarkers. A total 37 research papers were collected. conclude 8-OHdG is promising biomarker early prediction compared lipid protein
Language: Английский
Citations
1
Nature Communications, Journal Year: 2023, Volume and Issue: 14(1)
Published: Feb. 22, 2023
Women of reproductive age are a group particular concern with regards to vaccine uptake, related their unique considerations menstruation, fertility, and pregnancy. To obtain uptake data specific this group, we obtained surveillance from the Office for National Statistics, linked COVID-19 vaccination status Immunisation Management Service, England, 8 Dec 2020 15 Feb 2021; 13,128,525 such women at population-level, were clustered by (18-29, 30-39, 40-49 years), self-defined ethnicity (19 UK government categories), index multiple deprivation (IMD, geographically-defined IMD quintiles). Here show that among age, older White being in least-deprived each independently associated higher first second doses; however, exerts strongest influence (and weakest). These findings should inform future public messaging policy.
Language: Английский
Citations
16
Obstetrics & Gynecology Science, Journal Year: 2023, Volume and Issue: 66(4), P. 270 - 289
Published: May 17, 2023
The coronavirus disease 2019 (COVID-19) outbreak which started in December rapidly developed into a global health concern. Pregnant women are susceptible to respiratory infections and can experience adverse outcomes. This systematic review meta-analysis compared pregnancy outcomes according COVID-19 status. MEDLINE, EMBASE, Cochrane Library databases were searched for relevant articles published between 1, 2019, October 19, 2022. Main inclusion criterion was any population-based, cross-sectional, cohort, or case-control study that assessed with without laboratory-confirmed COVID-19. Sixty-nine studies including 1,606,543 pregnant (39,716 [2.4%] diagnosed COVID-19) retrieved. COVID-19-infected had higher risk of preterm birth (odds ratio [OR], 1.59; 95% confidence interval [CI], 1.42-1.78), preeclampsia (OR, 1.41; CI, 1.30-1.53), low weight 1.52; 1.30-1.79), cesarean delivery 1.20; 1.10-1.30), stillbirth 1.71; 1.39-2.10), fetal distress 2.49; 1.54-4.03), neonatal intensive care unit admission 2.33; 1.72-3.16), perinatal mortality 1.96; 1.15-3.34), maternal 6.15; 3.74-10.10). There no significant differences total miscarriage, premature rupture membranes, postpartum hemorrhage, cholestasis, chorioamnionitis infection. demonstrates infection during lead information could aid researchers clinicians preparing another pandemic caused by newly discovered viruses. findings this may assist evidence-based counseling help manage
Language: Английский
Citations
16
Vaccines, Journal Year: 2024, Volume and Issue: 12(4), P. 440 - 440
Published: April 18, 2024
COVID-19 vaccination rates are lower in women of reproductive age (WRA), including pregnant/postpartum women, despite their poorer COVID-19-related outcomes. We evaluated the experiences 3568 U.K. WRA, 1983 (55.6%) experiencing a pandemic pregnancy, recruited through ZOE COVID Symptom Study app. Two staggered online questionnaires (Oct–Dec 2021: 3453 responders; Aug–Sept 2022: 2129 responders) assessed status, vaccination, and attitudes for/against vaccination. Descriptive analyses included type(s), timing relative to age-based eligibility delay (first >28 days from eligibility), rationale, with content analysis free-text comments. Most responders (3392/3453, 98.2%) were vaccinated by Dec 2021, motivated altruism, supportiveness general, low risk, concerns. Few declined (by Sept/2022: 20/2129, 1.0%), citing risks (pregnancy-specific longer-term), pre-existing immunity, personal/philosophical reasons. delayed although (vs. other WRA) received later (median 3 vs. 0 after eligibility, p < 0.0001). Despite high uptake, concerns adverse effects, misinformation (including healthcare providers), ever-changing government advice, complex decision making. In summary, most this large WRA cohort promptly vaccinated, pregnant/post-partum women. Altruism community benefit superseded personal as reasons for Nevertheless, experienced angst vaccine-related discouragement. These findings should inform strategies WRA.
Language: Английский
Citations
6
Obstetrics and Gynecology, Journal Year: 2023, Volume and Issue: unknown
Published: Oct. 12, 2023
OBJECTIVE: To quantify pandemic-related changes in obstetric intervention and perinatal outcomes the United States. METHODS: We carried out a retrospective study of all live births fetal deaths States, 2015–2021, with data obtained from natality, death, linked birth–infant death files National Center for Health Statistics. Analyses were among singletons; singletons patients prepregnancy diabetes, hypertension, hypertensive disorders pregnancy; twins. Outcomes interest included preterm birth, labor induction or cesarean delivery, macrosomia, postterm death. Interrupted time series analyses used to estimate prepandemic period (January 2015–February 2020), at pandemic onset (March 2020–December 2021). RESULTS: The population 26,604,392 155,214 stillbirths. was characterized by temporal increases birth delivery rates reductions mortality. Pandemic associated absolute decreases (decrease 0.322/100 births, 95% CI 0.506–0.139) 0.190/100 0.334–0.047) macrosomia (increase 0.046/100 births), 0.015/100 0.501/1,000 total 0.220–0.783). These larger subpopulations high risk (eg, diabetes). Among decrease 1.634/100 births) 1.521/100 0.328/100 9.840/1,000 3.933–15.75). Most reversed months after onset. CONCLUSION: coronavirus disease 2019 (COVID-19) transient (especially delivery) increase
Language: Английский
Citations
9
BMJ Public Health, Journal Year: 2023, Volume and Issue: 1(1), P. e000314 - e000314
Published: Oct. 1, 2023
Background A few studies indicate that women infected with SARS-CoV-2 during pregnancy might have an increased risk of stillbirth. Our aim was to investigate the stillbirth according infection also taking variant into account. Methods We conducted a register-based study using Swedish, Danish and Norwegian birth registries. total 389 949 births (1013 stillbirths) after 22 completed gestational weeks between 1 May 2020 end follow-up (27 January 2022 for Sweden Norway; 31 December 2021 Denmark). estimated following Cox regression each country, combined results random-effects meta-analysis. Results associated (adjusted HR 2.40; 95% CI 1.22 4.71). The highest first infection, adjusted 5.48 (95% 3.11 9.63) 2 weeks, 4.38 2.41 7.98) 4 3.71 1.81 7.59) 6 weeks. Furthermore, greatest among Delta-dominated period 8.23; 3.65 18.59), more modest Index 3.66; 1.89 7.06) Alpha 2.73; 1.13 6.59) dominated periods. Conclusions found who were period.
Language: Английский
Citations
6
Pediatric Research, Journal Year: 2023, Volume and Issue: 95(2), P. 445 - 455
Published: Dec. 6, 2023
Language: Английский
Citations
6
Transactions of the Royal Society of Tropical Medicine and Hygiene, Journal Year: 2024, Volume and Issue: 118(7), P. 405 - 425
Published: Jan. 31, 2024
Abstract We aimed to estimate the associations between coronavirus disease 2019 (COVID-19) vaccination during pregnancy and risks of adverse perinatal outcomes. performed a literature search in PubMed, Web Science Embase identify eligible studies published up 24 September 2023, yielding 39 included studies. Pooled relative (RRs) with 95% confidence intervals (CIs) were calculated random effects model. The pooled results showed that COVID-19 (any type or dose any trimester) was not associated an increased risk In particular, third trimester decreased preterm birth (<37 weeks) (RR 0.85 [95% CI 0.74 0.98]), 5-min Apgar <7 0.87 0.78 0.97]) neonatal intensive care unit (NICU) admission 0.90 0.86 0.95]). inverse also found analysis one-dose miscarriage 0.83 0.72 0.96]) 0.80 1.00]) two-dose NICU 0.76 0.96]). does increase negative outcomes for mother baby.
Language: Английский
Citations
2