Cannabis for Chronic Pain: Mechanistic Insights and Therapeutic Challenges

Stresses, Journal Year: 2025, Volume and Issue: 5(1), P. 7 - 7

Published: Jan. 15, 2025

Chronic pain represents a complex and debilitating condition that affects millions of people worldwide, significantly compromising their quality life. The conventional approach to treating this type often relies on the use opioid analgesics anti-inflammatory drugs. While these agents are effective in short term, they present several limitations, including risk dependence, severe side effects, and, some cases, ineffectiveness reducing pain. In context, medical cannabis has emerged as promising therapeutic alternative, given its potential ability relieve effectively with favorable safety profile. This work aims provide comprehensive up-to-date review existing literature effects treatment chronic Cannabis sativa contains pharmacologically active compounds, most prominent which delta-9-tetrahydrocannabinol (∆9-THC) cannabidiol (CBD), interact body’s endocannabinoid system, thereby modulating response. Clinical evidence shown cannabinoids can reduce intensity pain, particularly cases neuropathy, multiple sclerosis, arthritis, other painful conditions unresponsive treatments. However, full integration into clinical practice faces significant obstacles, need for standardized dosing, long-term data, regulatory frameworks. These issues, alongside concerns over adverse drug interactions, must be addressed unlock cannabinoids, patients, who endure both physical suffering added burden stress.

Language: Английский

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Medicinal Cannabis: A Potential Tool for Managing Chronic Pain and Mental Health in Asia

Journal of Pain & Palliative Care Pharmacotherapy, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 2

Published: Dec. 11, 2024

Language: Английский

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