Analysis of Hospital-Acquired Infections in a Chinese Specialized Rehabilitation Hospital: A Five-Year Surveillance Study (2020-2024) DOI Creative Commons
Qianfeng Li, Dong Wang,

Hanyuan Fan

et al.

Infection and Drug Resistance, Journal Year: 2025, Volume and Issue: Volume 18, P. 2377 - 2388

Published: May 1, 2025

Hospital-acquired infections (HAIs) pose significant challenges in rehabilitation hospitals, particularly affecting patients with extended stays and complex medical needs. This study analyzed HAI patterns risk factors a Chinese hospital from 2020 to 2024. A retrospective observational was conducted at tertiary-care 25 specialized wards. Data collection included patient demographics, clinical parameters, ward-level characteristics. Statistical analysis employed Poisson Quasi-Poisson regression models identify factors, comprehensive diagnostic evaluation. The revealed an overall infection rate of 3.64%, representing 385 among 10,559 inpatients. Vegetative State Awakening Department exhibited the highest 11.1%, followed by Geriatric Rehabilitation (8.2%), Neuro wards (5.5-7.0%). Respiratory tract were most common (42%), ventilator-associated pneumonia accounting for 28% all infections. identified several through both models. In more reliable model that accounted overdispersion, tracheal intubation emerged as strongest predictor coefficient 2.02 (p < 0.001), use glucocorticoids (coefficient: 1.78, p 0.001). While initial suggested protective effect radiation therapy, this not model. highlights critical role glucocorticoid development within settings. variability rates suggests need tailored control strategies. Implementation targeted interventions focusing on these could help reduce incidence hospitals.

Language: Английский

Isolation of vanA-Mediated Vancomycin-Resistant Enterococcus faecalis (ST1912/CC116) and Enterococcus faecium (ST80/CC17), optrA-Positive Linezolid-Resistant E. faecalis (ST32, ST1902) from Human Clinical Specimens in Bangladesh DOI Creative Commons

Sangjukta Roy,

Meiji Soe Aung, Shyamal Kumar Paul

et al.

Antibiotics, Journal Year: 2025, Volume and Issue: 14(3), P. 261 - 261

Published: March 4, 2025

Background/Objectives: Enterococcus is one of the major nosocomial pathogens. The present status antimicrobial resistance determinants and virulence factors was analyzed for current causing infectious diseases in Bangladesh. Methods: Clinical isolates recovered from various specimens a tertiary care hospital were analyzed. Antimicrobial susceptibility measured by broth microdilution test, genes/virulence detected uniplex/multiplex PCR, along with sequencing analysis as required. sequence type (ST) E. faecalis faecium identified based on multilocus typing (MLST) scheme. Results: For one-year period, total 143 (135 faecalis, 7 faecium, 1 hirae) collected. Although all susceptible to penicillin, high rates noted against erythromycin (87%) levofloxacin (62%). High-level gentamicin 30% 86% faecium. Vancomycin due vanA isolate each (ST1912, CC116) (ST80, CC17). Three (2.2%) ST32 or ST1902 resistant linezolid, harboring optrA-fexA. Conclusions: study identifies vancomycin-resistant humans Bangladesh shows potential spread optrA multiple lineages faecalis.

Language: Английский

Citations

0
Analysis of Hospital-Acquired Infections in a Chinese Specialized Rehabilitation Hospital: A Five-Year Surveillance Study (2020-2024) DOI Creative Commons
Qianfeng Li, Dong Wang,

Hanyuan Fan

et al.

Infection and Drug Resistance, Journal Year: 2025, Volume and Issue: Volume 18, P. 2377 - 2388

Published: May 1, 2025

Hospital-acquired infections (HAIs) pose significant challenges in rehabilitation hospitals, particularly affecting patients with extended stays and complex medical needs. This study analyzed HAI patterns risk factors a Chinese hospital from 2020 to 2024. A retrospective observational was conducted at tertiary-care 25 specialized wards. Data collection included patient demographics, clinical parameters, ward-level characteristics. Statistical analysis employed Poisson Quasi-Poisson regression models identify factors, comprehensive diagnostic evaluation. The revealed an overall infection rate of 3.64%, representing 385 among 10,559 inpatients. Vegetative State Awakening Department exhibited the highest 11.1%, followed by Geriatric Rehabilitation (8.2%), Neuro wards (5.5-7.0%). Respiratory tract were most common (42%), ventilator-associated pneumonia accounting for 28% all infections. identified several through both models. In more reliable model that accounted overdispersion, tracheal intubation emerged as strongest predictor coefficient 2.02 (p < 0.001), use glucocorticoids (coefficient: 1.78, p 0.001). While initial suggested protective effect radiation therapy, this not model. highlights critical role glucocorticoid development within settings. variability rates suggests need tailored control strategies. Implementation targeted interventions focusing on these could help reduce incidence hospitals.

Language: Английский

Citations

0