Advances in Aging Research, Journal Year: 2024, Volume and Issue: 13(06), P. 121 - 135
Published: Jan. 1, 2024
Language: Английский
Expert Review of Anti-infective Therapy, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 23, 2025
Lower respiratory infections have a huge impact on global health, especially in older individuals, immunocompromised people, and those with chronic comorbidities. The COVID-19 pandemic highlights the importance of vaccination. However, there are lower rates vaccination adult population that commonly due to missed opportunity vaccinate. Vaccination offers best strategy prevent hospitalization, complications, death caused by infections. In this review, authors provide an overview vaccines for population. review available data about preventing infections, focusing pneumococcal vaccine, influenza vaccines, syncytial virus (RSV) vaccines. discuss currently scientific evidence role against Finally, current recommendations Scientific effectiveness is important. An efficient implementation immunization strategies will decrease burden Recognizing existing their essential achieve high rate
Language: Английский
Citations
1
Infectious Disease Reports, Journal Year: 2025, Volume and Issue: 17(1), P. 14 - 14
Published: Feb. 11, 2025
Case Report: We report a case of 37-year-old female with kidney transplant, who was admitted at our hospital due to worsening renal function, nephrotic proteinuria, and anemia developed 21 days after the second dose BNT162b2 COVID-19 vaccine (Pfizer-BioNTech). Laboratory tests revealed hemolytic anemia, thrombocytopenia, acute injury. Given clinical picture Thrombotic Micro-angiopathy (TMA) severe impairment, plasma exchange (PEX) dialysis were immediately started. workup showed low C3 C4 levels, normal activity ADAMTS13, absence anti-factor H antibodies. Molecular biology investigations heterozygous variant in exon 22 (SCR20) CFH gene (c.3628C>T; p.Arg1210Cys) described as an atypical Hemolytic Uremic Syndrome (aHUS) causative mutation. Our patient completed two sessions PEX followed by eculizumab treatment hematological improvement but no recovery function. This is first reported aHUS triggered SARS-CoV-2 vaccination transplant without Conclusion: Although rare, clinicians should be aware possible nephrological complications that may appear vaccination.
Language: Английский
Citations
0
Seminars in Respiratory and Critical Care Medicine, Journal Year: 2025, Volume and Issue: unknown
Published: March 31, 2025
Abstract Whenever a new COVID-19 vaccination season starts, we must face challenges, including which vaccines to use, the update of high-risk groups be vaccinated, and especially type amount information communicated people in order promote vaccination. recommendations should fit these specific conditions. The use effective against predominant SARS-CoV-2 virus variants extent immune response (waning immunity) are key aspects try protect better populations. Updated currently swiftly available. However, number vaccinated with any additional booster dose is declining. Improved health training for care professionals, together tools make simpler recommendations, can encourage higher rates. Addressing challenges essential improve coverage ensure adequate protection evolving threats. has become constant presence our society. changes but neither endemic nor seasonal so far. Omicron variant prevailed nearly 2 years now several its subvariants like JN.1, KP.2, or XEC dominant ones. In this moving situation, main message same: safe effective. role current efforts mitigate severity disease reduce risk complications death, instead preventing most infections. New at different stages clinical research.
Language: Английский
Citations
0
Vaccines, Journal Year: 2025, Volume and Issue: 13(6), P. 554 - 554
Published: May 23, 2025
The COVID-19 pandemic posed a huge challenge to global health systems. In addition searching for effective methods of treating and preventing infection with new pathogen, we could once again observe that severe respiratory its complications can be become challenging problem cardiac patients. Empirical observations are fully confirmed by the results clinical trials. Patients risk factors already diagnosed cardiovascular diseases particularly exposed course COVID-19, including death. That is why consider it so important promote vaccinations against as safe method serious infections in this special group patients, accordance updated recommendations relevant experts. If an detected, depending on form hospitalization, there also several antiviral treatment strategies. Nirmatrelvir/ritonavir therapy selected patient groups, but use requires analysis pharmacotherapy regimen context potentially significant drug interactions.
Language: Английский
Citations
0
Deleted Journal, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 3, 2025
Citations
0
Bulletin of Russian State Medical University, Journal Year: 2024, Volume and Issue: 2024(5)
Published: Oct. 1, 2024
mRNA vaccines turned out to be highly effective in combating the COVID-19 pandemic and other viral infections. Despite extensive study of last five years, issue safety their use is still relevant. The aimed assess immunogenicity two anti-tuberculosis vaccine doses female male rats 2 4 weeks after vaccination. Hematological biochemical parameters blood were determined within same timeframe. dose-dependent nature was confirmed both females males. Vaccination led moderate lymphopenia neutrophilia rats, as well apparent sex-related changes biochemistry at various time points. findings suggest toxicity importance assessing its toxic effects points animals sexes.
Language: Английский
Citations
1
Advances in Aging Research, Journal Year: 2024, Volume and Issue: 13(06), P. 121 - 135
Published: Jan. 1, 2024
Language: Английский
Citations
0