Bronchoscopy and molecular diagnostic techniques to identify superimposed infections in COVID-19-associated ARDS: a case series from Ecuador during the second wave DOI Creative Commons
Killen H. Briones‐Claudett,

Mónica H. Briones-Claudett,

Roger Murillo Vasconez

et al.

Frontiers in Medicine, Journal Year: 2024, Volume and Issue: 11

Published: Oct. 30, 2024

COVID-19-associated acute respiratory distress syndrome (CARDS) poses significant challenges in resource-limited settings. This case series explores the role of bronchoscopy and molecular techniques identifying superimposed infections CARDS patients during second wave pandemic Ecuador.

Language: Английский

Emergence and spread of the SARS-CoV-2 omicron (BA.1) variant across Africa: an observational study DOI Creative Commons
Carlo Fischer, Tongai Maponga, Anges Yadouléton

et al.

The Lancet Global Health, Journal Year: 2025, Volume and Issue: 13(2), P. e256 - e267

Published: Jan. 29, 2025

Language: Английский

Citations

2
Epidemiology of HIV, Hepatitis B Virus, and Hepatitis C Virus in Incoming Venezuelan Migrants: A Laboratory-Based Cross-Sectional Study, 2021-2023 DOI
Felix Lehmann, Ruth Aralí Martínez-Vega, Andrés Moreira‐Soto

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
“Strengthening Diagnostic Services in Latin America Requires Regional Leadership, Sustainable Funding, and Enhanced Data Sharing” DOI Creative Commons
Andrés Moreira‐Soto,

Nils Gade,

Bert Hoffmann

et al.

Health Policy, Journal Year: 2025, Volume and Issue: unknown, P. 105287 - 105287

Published: March 1, 2025

Diagnostic services played a key role in government responses to the COVID-19 pandemic. In our work support diagnostics over 20 countries of Global South, with focus on Latin America, we observed common problems resource-limited settings. We identify constraints (i) affordability reagents, (ii) access (iii) poor infrastructure, and (iv) limited human resources. Enhancing diagnostic settings cannot be sustained only by international cooperation philanthropic missions. Success depends domestic leadership regional which existent influenza or dengue networks America are prime examples. A American Center for Disease Control Prevention (CDC), as proposed some, can successful if reliable funding clear mandate secured. stronger inclusion tool development data sharing will imperative dealing emerging pathogens.

Language: Английский

Citations

0
Venezuelan Equine Encephalitis, Peruvian Amazon, 2020 DOI
Marta Piche-Ovares, María Mendoza, Andrés Moreira‐Soto

et al.

Emerging infectious diseases, Journal Year: 2025, Volume and Issue: 31(5)

Published: April 24, 2025

We screened 1,972 febrile patients from the Peruvian Amazon in 2020-2021 for Venezuelan equine encephalitis virus (VEEV). Neutralizing antibody detection rate was 3.9%; 2 were PCR positive. Genome identity compared to Peru VEEV subtype ID strains 97.6%-98.1%. Evidence purifying selection and ancestry ≈54 years ago corroborated endemicity.

Language: Английский

Citations

0
Post-migration infection with SARS-CoV-2 in Venezuelan migrants: a laboratory-based epidemiological observational study DOI Creative Commons
Edmilson Ferreira de Oliveira-Filho, Ruth Aralí Martínez-Vega, Andrés Moreira‐Soto

et al.

Travel Medicine and Infectious Disease, Journal Year: 2024, Volume and Issue: unknown, P. 102772 - 102772

Published: Oct. 1, 2024

Language: Английский

Citations

2
Serologic evidence for early SARS-CoV-2 circulation in Lima, Peru, 2020 DOI Creative Commons
Andrés Moreira‐Soto, María Mendoza,

Gloria Arotinco-Garayar

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 14, 2024

Abstract During early 2021, Peru had the highest COVID-19-associated per-capita mortality rate globally. Socioeconomic inequality and insufficiently prepared healthcare surveillance systems likely contributed to high mortality, potentially coupled with SARS-CoV-2 introduction. We tested 1,441 individuals fever sampled during August 2019-May 2021 in Lima, Peru, for SARS-CoV-2-specific antibodies. Serologic testing included a chemiluminescence immunoassay confirmatory surrogate virus neutralization testing. Early positive samples (n=24) from January-March 2020 were further using plaque-reduction avidity tests based on spike nucleoprotein antigens. None of PRNT-confirmed, contrast 81.8% (18/22) subsample April onwards (Fischer-exact test, p<0.0001). antibody detection was 0.9% mid-April (1/104; 95% confidence interval (CI), 0.1-5.8%), suggesting onset viral circulation early-mid March 2020, consistent first molecular 6th. Mean increase 62-77% 81-94% all PRNT-confirmed late February/March 2020. confirmed Susceptible, Exposed, Infected Recovered mathematical model that projected an effective reproduction number >1, February-March Robust serologic thus introduction COVID-19 Peru. Emphasizing role diagnostic confirmation, our study highlights importance accurate managing infectious disease outbreaks. Importance Latin America hard hit by pandemic. Reasons include inadequate preparation socio-economic vulnerabilities, exacerbated undetected circulation. Diagnostic requires exhaustive validation due unspecific reactivity. used cohort circa 1400 febrile patients 2019 until May months earlier than seroprevalence two-step algorithm. antibodies onwards, SARS-CoV-2-detection. significant modeled peak >1 Using validation, we detected severe impact

Language: Английский

Citations

0
Bronchoscopy and molecular diagnostic techniques to identify superimposed infections in COVID-19-associated ARDS: a case series from Ecuador during the second wave DOI Creative Commons
Killen H. Briones‐Claudett,

Mónica H. Briones-Claudett,

Roger Murillo Vasconez

et al.

Frontiers in Medicine, Journal Year: 2024, Volume and Issue: 11

Published: Oct. 30, 2024

COVID-19-associated acute respiratory distress syndrome (CARDS) poses significant challenges in resource-limited settings. This case series explores the role of bronchoscopy and molecular techniques identifying superimposed infections CARDS patients during second wave pandemic Ecuador.

Language: Английский

Citations

0