The Journal of Cell Biology, Journal Year: 2025, Volume and Issue: 224(4)
Published: March 17, 2025
Multivesicular bodies (MVBs) are crucial for membrane protein degradation and lipid homeostasis. A recent study by Gao colleagues (https://doi.org/10.1083/jcb.202410013) identifies Any1 as a phospholipid scramblase that plays an important role in MVB biogenesis coordinating remodeling with transfer through Vps13 at organelle contact sites.
Language: Английский