The Impact of Childhood Abuse and Neglect on the Development of Features of Polycystic Ovary Syndrome: A Pilot Study DOI Creative Commons
Akanksha Misra,

Olivia Wolfe,

Ricardo Azziz

et al.

Women s Health Reports, Journal Year: 2025, Volume and Issue: 6(1), P. 412 - 420

Published: Jan. 1, 2025

To determine associations of childhood emotional and physical abuse neglect with the incidence menstrual irregularity, male pattern hair growth, possible PCOS. Cross-sectional Study at University. 410 individuals, 18-45 years old. Survey. A questionnaire was administered to students, faculty, staff a regional State University New York (SUNY) campus. Data on sociodemographic factors, dysfunction (irregularity, PCOS), experiences were collected. Participants sub-grouped into those irregularity (MI: defined as >35 days between one period's beginning next, or ≤8 cycles/year, absent periods altogether), growth (MHG: excess upper lip, chin, chest, abdomen, buttocks, back), both (MI+MHG), who did have neither (Unaffected). Family income status yielded some association presence MI, MHG, MI+MHG. There significant correlations individuals reporting MI+MHG reported feeling loved by their caregiver (p value = 0.0029988), experiencing verbal 0.0000004293), 0.030228), emotionally disconnected from 0.0006138), not having peaceful home 0.00005760630462), vis-à-vis Unaffected individuals. Almost all respondents prior diagnosis PCOS (97.6%) MI and/or MHG. All neglect, except loss parent, significantly associated features suggestive Larger, unbiased population studies across different demographics, are needed.

Language: Английский

The impact of adverse childhood experiences on multimorbidity: a systematic review and meta-analysis DOI Creative Commons
Dhaneesha Senaratne, Bhushan Thakkar, Blair H. Smith

et al.

BMC Medicine, Journal Year: 2024, Volume and Issue: 22(1)

Published: Aug. 15, 2024

Abstract Background Adverse childhood experiences (ACEs) have been implicated in the aetiology of a range health outcomes, including multimorbidity. In this systematic review and meta-analysis, we aimed to identify, synthesise, quantify current evidence linking ACEs Methods We searched seven databases from inception 20 July 2023: APA PsycNET, CINAHL Plus, Cochrane CENTRAL, Embase, MEDLINE, Scopus, Web Science. selected studies investigating adverse events occurring during (< 18 years) an assessment multimorbidity adulthood (≥ years). Studies that only assessed or outcomes children were excluded. Risk bias was using ROBINS-E tool. Meta-analysis prevalence dose–response meta-analysis methods used for quantitative data synthesis. This pre-registered with PROSPERO (CRD42023389528). Results From 15,586 records, 25 eligible inclusion (total participants = 372,162). The exposure ≥ 1 48.1% (95% CI 33.4 63.1%). 34.5% 23.4 47.5%). Eight provided sufficient 197,981). There significant dose-dependent relationship between ACE ( p < 0.001), every additional contributing 12.9% 7.9 17.9%) increase odds However, there heterogeneity among included I 2 76.9%, Cochran Q 102, 0.001). Conclusions is first synthesise literature on multimorbidity, showing across large number participants. It consolidates enhances extensive body shows association individual long-term conditions, risky behaviours, other poor outcomes.

Language: Английский

Citations

11
Recent life events and adverse childhood experiences in predicting antenatal depression and anxiety: cross-sectional study DOI

Benedicte M Zilmer,

Gritt Overbeck, Volkert Siersma

et al.

Family Practice, Journal Year: 2025, Volume and Issue: 42(1)

Published: Jan. 17, 2025

Abstract Background Antenatal depression and anxiety are associated with preterm labour, low birth weight, postpartum depression, can impact the emotional mental development of child. Both adverse childhood experiences recent stressful events linked to negative health outcomes. However, certain may be more impactful than others. Objective This study aims investigate most important types stressors that help in identifying pregnant women need psychological support. Methods observational examines data from FamilieTrivsel trial, which between 6 10 weeks gestation were recruited by general practitioners. All participants asked complete questionnaires. Mental was assessed Hospital Anxiety Depression Score (HADS). Potential contributory risk factors identified using Recent Life Events Questionnaire Adverse Childhood Experiences questionnaire. The relative importance various analysed a dominance analysis, direction their association determined multivariable linear regression analysis. Results Of specific life events, serious problems friend, divorce, racial harassment, unemployment, financial difficulties, moving house had strongest associations poor health, along experience illness household. Growing up an physical neglect parental divorce were, paradoxically, lower HADS scores. Conclusions have stronger postnatal implying it might useful for clinicians providing routine antenatal care gather information on stressors.

Language: Английский

Citations

0
Examining the role of social determinants of health in maternal mental health screening and treatment engagement during the perinatal period DOI Creative Commons
Leah Holcomb,

Lizmarie Maldonado,

Paul J. Nietert

et al.

Biology of Sex Differences, Journal Year: 2025, Volume and Issue: 16(1)

Published: Feb. 12, 2025

Abstract Background Maternal mental health conditions are associated with unmet Social Determinants of Health (SDOH) needs and can impede access to substance use disorder (SUD) treatment, leading poor maternal newborn outcomes. A text/phone-based screening referral treatment intervention, Listening Women Pregnant Postpartum People (LTWP), has demonstrated improved rates screening, positive for concerns, attendance SUD compared usual care (i.e., in-person referral). It is unknown, however, if LTWP improves identification individuals SDOH needs. This study examines positive, among those not experiencing Methods secondary analysis includes participants randomized endorsing one or more need (n = 78) no 103) measured by the Accountable Communities Health-Related Needs Screening Tool via an online survey. Differences in groups' completing a being referred attending were between groups using chi-square tests relative risk as measure association. Adjustments missing data multiple imputations performed full cohort at least 106) 118). Results Among participants, 43.0% (78/181) reported financial strain (55.1% (43/78)), disabilities (34.6% (27/78)), food insecurity (33.3% (26/78)) most frequently SDOH. On average, significantly younger (29.0 vs. 32.0 years), likely self-identify non-Hispanic Black (42.3% vs 13.6%), report lower household annual income 1.9% under $25,000), without Those screen concerns (RR: 1.59; 95% CI: 1.21–2.09), be 2.97; 1.36–6.48), attend 2.64; CI 1.04–2.73) Conclusions The simple text- phone-based approach needed, shows promise increasing social determinants demonstrates potential enhance identification, perinatal disorders traditional systems.

Language: Английский

Citations

0
Adverse Childhood Experiences (ACEs) Screening in Primary Care Settings for Adults: A Systematic Review DOI Creative Commons
Betül Küçükardalı, Angela L. Lamson, Natalia Sira

et al.

Journal of Child & Adolescent Trauma, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 12, 2025

Language: Английский

Citations

0
Stress during puberty and adulthood pregnancy impact histone acetylation regulators in the hypothalamus DOI

Laiklyn A M Luther,

Samantha L. Higley,

Kathleen E. Morrison

et al.

Neuroscience, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

0
The Impact of Childhood Abuse and Neglect on the Development of Features of Polycystic Ovary Syndrome: A Pilot Study DOI Creative Commons
Akanksha Misra,

Olivia Wolfe,

Ricardo Azziz

et al.

Women s Health Reports, Journal Year: 2025, Volume and Issue: 6(1), P. 412 - 420

Published: Jan. 1, 2025

To determine associations of childhood emotional and physical abuse neglect with the incidence menstrual irregularity, male pattern hair growth, possible PCOS. Cross-sectional Study at University. 410 individuals, 18-45 years old. Survey. A questionnaire was administered to students, faculty, staff a regional State University New York (SUNY) campus. Data on sociodemographic factors, dysfunction (irregularity, PCOS), experiences were collected. Participants sub-grouped into those irregularity (MI: defined as >35 days between one period's beginning next, or ≤8 cycles/year, absent periods altogether), growth (MHG: excess upper lip, chin, chest, abdomen, buttocks, back), both (MI+MHG), who did have neither (Unaffected). Family income status yielded some association presence MI, MHG, MI+MHG. There significant correlations individuals reporting MI+MHG reported feeling loved by their caregiver (p value = 0.0029988), experiencing verbal 0.0000004293), 0.030228), emotionally disconnected from 0.0006138), not having peaceful home 0.00005760630462), vis-à-vis Unaffected individuals. Almost all respondents prior diagnosis PCOS (97.6%) MI and/or MHG. All neglect, except loss parent, significantly associated features suggestive Larger, unbiased population studies across different demographics, are needed.

Language: Английский

Citations

0