Effectiveness of an Email-Based, Semaglutide-Supported Weight-Loss Service for People with Overweight and Obesity in Germany: A Real-World Retrospective Cohort Analysis
Louis Talay,
No information about this author
Matt Vickers,
No information about this author
Laura Ruiz
No information about this author
et al.
Obesities,
Journal Year:
2024,
Volume and Issue:
4(3), P. 256 - 269
Published: July 24, 2024
Quality
glucose-like
peptide-1
receptor
agonist
(GLP-1
RA)-supported
digital
weight-loss
services
(DWLSs)
have
the
potential
to
play
a
significant
role
in
shifting
alarming
global
obesity
rate.
Previous
studies
demonstrated
various
aspects
of
their
utility
Australian
and
British
populations,
but
nothing
has
hitherto
been
investigated
real-world
European
settings,
where
GLP-1
RA
weight
therapy
healthcare
are
widely
used.
This
study
retrospectively
analysed
5-month
(Mean
=
160.14
days)
outcomes
cohort
patients
who
received
email-based
health
coaching
Semaglutide
via
Juniper
Germany
DWLS
(n
833).
Mean
loss
was
9.52
(±5.46)
percent,
with
81.51%
losing
‘meaningful’
(5%
or
more)
amount
weight.
Females
9.75)
tended
lose
more
than
males
8.41)
from
lowest
two
BMI
categories
(27.5–29.99
kg/m2
10.1;
30–34.99
9.74)
lost
significantly
those
highest
category
(≥40
8.11).
These
findings
indicate
that
RA-supported
DWLSs
can
contribute
meaningful
Germany.
Future
research
should
seek
conduct
dedicated
adherence
analysis
measure
effect
subsidisation
baseline
body
mass
index
on
general
effectiveness.
Language: Английский
Dispensing Error Rate in an App-Based, Semaglutide-Supported Weight-Loss Service: A Retrospective Case Study
Louis Talay,
No information about this author
Matt Vickers
No information about this author
Published: July 1, 2024
Digital
weight-loss
services
(DWLSs)
combining
pharmacotherapy
and
health
coaching
have
the
potential
to
make
a
major
contribution
global
struggle
against
obesity.
However,
there
is
currently
no
evidence
counter
widespread
concern
that
these
enable
large
numbers
of
unsuitable
patients
obtain
Glucagon-like
peptide-1
receptor
agonists
(GLP-1
RA).
This
study
retrospectively
analysed
rate
at
which
partner
pharmacy
network
Australia’s
largest
DWLS
provider
committed
GLP-1
RA
dispensing
errors
over
6-month
period.
The
analysis
found
191
(0.14%)
135131
dispensed
Semaglutide
orders
contained
an
error.
Non-compliant
dose
escalation
(44.5%)
dispatch
(32.5%)
were
two
most
common
error
types.
Most
(89%)
deemed
been
medium
urgency,
with
6.8%
considered
high
urgency.
A
disproportionate
number
urgency
cases
from
wrong
medication
(31%)
general
complaint
(15%).
Chi-square
test
revealed
statistically
higher
among
female
(0.16%)
compared
males
(0.076%).
results
lay
important
foundation
in
digital
literature
suggest
comprehensive
DWLSs
safely
collaborate
third-party
pharmacies
RAs.
Language: Английский
The Dispensing Error Rate in an App-Based, Semaglutide-Supported Weight-Loss Service: A Retrospective Cohort Study
Louis Talay,
No information about this author
Matt Vickers
No information about this author
Pharmacy,
Journal Year:
2024,
Volume and Issue:
12(5), P. 135 - 135
Published: Sept. 3, 2024
Digital
weight-loss
services
(DWLSs)
combining
pharmacotherapy
and
health
coaching
have
the
potential
to
make
a
major
contribution
global
struggle
against
obesity.
However,
degree
which
DWLSs
compromise
patient
safety
through
dispensation
of
Glucagon-like
peptide-1
receptor
agonist
(GLP-1
RA)
medications
is
unknown.
This
study
retrospectively
analysed
rate
at
patients
reported
GLP-1
RA
dispensing
errors
from
patient-selected
partner
pharmacies
Australia's
largest
DWLS
provider
over
six-month
period.
The
analysis
found
that
99
(0.35%)
28,165
dispensed
semaglutide
orders
contained
an
error.
Incorrect
dose
(58.6%)
unreasonable
medication
expiry
window
(21.2%)
were
two
most
common
error
types.
Most
(84.9%)
deemed
been
medium
urgency,
with
11.1%
being
considered
high-urgency
errors.
doses
(45.5%)
supplies
wrong
(36.3%)
comprised
in
cases.
Female
more
than
male
(0.41%
vs.
0.12%,
Language: Английский
GLP-1 RA Prescribing Errors in a Multidisciplinary Digital Weight-Loss Service: A Retrospective Quantitative Analysis
Louis Talay,
No information about this author
Matt Vickers,
No information about this author
Sarah Fuller
No information about this author
et al.
Healthcare,
Journal Year:
2024,
Volume and Issue:
12(20), P. 2093 - 2093
Published: Oct. 21, 2024
Digital
weight
loss
services
(DWLSs)
that
use
Glucagon-like
peptide-1
receptor
agonists
(GLP-1
RAs)
have
demonstrated
potential
in
contributing
to
a
shift
global
obesity
rates.
However,
reasonable
concerns
been
raised
about
the
prescribing
safety
of
these
services.
Prior
this
study,
electronic
had
only
investigated
hospital
settings
and
community
clinics.
Language: Английский
Weight Loss and Engagement in a Tirzepatide-Supported Digital Obesity Program: A Four-Arm Patient-Blinded Retrospective Cohort Study
Louis Talay,
No information about this author
Matt Vickers,
No information about this author
Catherine Bell
No information about this author
et al.
Telemedicine Reports,
Journal Year:
2024,
Volume and Issue:
5(1), P. 311 - 321
Published: April 1, 2024
Language: Английский
The Effect of Lifestyle Coaching Design on Patient Engagement and Weight Loss in Non-diabetic Patients of a Semaglutide-Supported Digital Obesity Program in the UK: A Comparative Retrospective Cohort Study
Louis Talay,
No information about this author
Matt Vickers,
No information about this author
Leif Lagesen
No information about this author
et al.
Cureus,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 23, 2024
Digital
weight-loss
services
(DWLSs)
that
supplement
continuous
lifestyle
coaching
with
semaglutide
therapy
have
shown
promise
in
delivering
and
effective
obesity
care.
However,
the
extent
to
which
design
influences
patient
engagement
program
effectiveness
is
unknown.
This
study
retrospectively
analysed
several
markers
weight
loss
percentage
over
16
weeks
a
large
semaglutide-supported
DWLS
UK
(n=154).
The
comparative
analysis
found
patients
who
received
was
proactive
personalised
sent
statistically
higher
number
of
messages
their
health
coach
(Mean=19.37
vs
Mean=8.55)
opened
app
more
frequently
(Mean
=
49.31
days
Mean
40.06
days)
than
whose
reactive
standardised.
16-week
10.1%
group
compared
8.9%
group,
but
difference
not
significant.
A
two-sample
t-test
female
9.76%)
tended
lose
male
6.88%),
(t(152)
1.89,
p
0.04).
findings
add
vital
layers
nuance
emerging
literature
on
DWLSs,
indicating
proactive,
approach
leads
better
engagement,
such
correlated
short-term
or
adherence
outcomes.
Moreover,
cohort's
comparably
mean
relative
previous
real-world
studies
lend
support
advice
leading
global
institutions
using
medication
only
as
an
adjunct
multidisciplinary
therapy.
Investigators
should
expand
this
research
by
conducting
comparable
longer
period
medication-only
control
groups.
Language: Английский
Why People Seek Obesity Care Through Digital Rather Than In-Person Services: A Quantitative Multinational Analysis of Patients From a Large Unsubsidized Digital Obesity Provider
Louis Talay,
No information about this author
Matt Vickers
No information about this author
Cureus,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 12, 2024
Digital
modalities
have
been
demonstrated
to
improve
access
and
adherence
various
chronic
care
services
by
mitigating
geographical,
temporal,
psychological
barriers
ongoing
multidisciplinary
consultations,
which
such
diseases
necessitate.
The
net
utility
of
medication-supported
digital
weight-loss
(DWLSs)
has
intensely
debated
over
the
past
few
years
due
their
rapid
uptake
against
backdrop
obesity
epidemic.
However,
research
on
these
in
real-world
settings
is
scarce.
Patients
a
large
multinational
DWLS
were
emailed
four-question
survey,
soliciting
reasons
for
using
service
instead
face-to-face
(F2F)
alternatives.
Responses
collected
from
1,283
patients,
including
481
United
Kingdom,
428
Germany,
374
Australia.
Personal
discomfort
discussing
weight
loss
F2F
was
most
common
reason
subscribing
Eucalyptus
across
full
cohort
(N
=
557,
43.41%),
followed
modality's
flexibility
441,
34.37%),
patient
inability
comprehensive
through
local
general
practitioner
(GP)
435,
33.90%),
marketing
or
brand
awareness
358,
27.90%).
Several
significant
differences
observed
between
country,
gender,
ethnicity,
regular
GP
status
each
subscription
reasons.
This
study
contributed
another
important
layer
emerging
literature
DWLSs
generating
preliminary
quantitative
evidence
benefits
access.
findings
also
indicated
that
certain
number
patients
may
be
simply
medications
rather
than
care.
To
derive
clearer
conclusions
about
this
concern,
follow-up
studies
should
aim
analyze
health
coaching
engagement
markers
range
providers.
Language: Английский
The effectiveness and sustainability of health outcomes from a holistic digital weight‐loss service with concomitant initiation of tirzepatide: A pragmatic randomized controlled trial in the UK
Louis Talay,
No information about this author
Matt Vickers,
No information about this author
Omar Alvi
No information about this author
et al.
Diabetes Obesity and Metabolism,
Journal Year:
2024,
Volume and Issue:
26(11), P. 4854 - 4863
Published: Sept. 2, 2024
To
measure
the
effectiveness
and
sustainability
of
Juniper
UK
digital
weight-loss
service
(DWLS),
which
delivers
6
months
personalized,
proactive
lifestyle
coaching
supplemented
with
tirzepatide
to
patients
through
a
multidisciplinary
team
(MDT).
Language: Английский
The Utility of a Digital Glucose‐Like Peptide‐1 Receptor Agonist‐Supported Weight‐Loss Service in Regional Australia: A Qualitative Analysis of Interviews With Current Patients of the Eucalyptus Program
Louis Talay,
No information about this author
Matt Vickers,
No information about this author
Sarah Loftus
No information about this author
et al.
Australian Journal of Rural Health,
Journal Year:
2024,
Volume and Issue:
33(1)
Published: Dec. 31, 2024
Against
the
backdrop
of
alarming
obesity
rates
and
growing
concerns
about
access
to
specialist
care
across
Australia,
this
study
aims
assess
utility
nation's
largest
digital
weight-loss
service
(DWLS)
in
regional
Australia.
Language: Английский