EAT‐Lancet Diet Pattern, Genetic Predisposition, Inflammatory Biomarkers, and Risk of Lung Cancer Incidence and Mortality DOI
Fubin Liu,

Changyu Si,

Linlin Chen

et al.

Molecular Nutrition & Food Research, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 5, 2024

Scope The association between a planetary and sustainable EAT‐Lancet diet lung cancer remains inconclusive, with limited exploration of the role genetic susceptibility inflammation. Methods results study includes 175 214 cancer‐free participants in UK Biobank. Fourteen food components are collected from 24‐h dietary recall questionnaire. A polygenic risk score is constructed through capturing overall variants for cancer. Sixteen inflammatory biomarkers assayed blood samples. Participants highest scores (≥12) have lower incidence (hazard ratio [HR] = 0.64, 95% confidence interval [CI]: 0.51–0.80) mortality (HR 0.65, CI: 0.48–0.88), compared to those lowest (≤8). Interestingly, there significantly protective trend against both adenocarcinoma squamous cell carcinoma higher scores. Despite no significant interactions, reduction observed increasing decreasing risk. Ten partially mediate Conclusion depicts conferred by associated inflammation levels among individuals diverse predispositions.

Language: Английский

EAT-Lancet Diet Pattern, genetic risk, and risk of colorectal cancer: a prospective study from the UK Biobank DOI
Fulan Hu, Jia‐Cheng Liu, Li D

et al.

American Journal of Clinical Nutrition, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

0

The Two Dimensions of Nutrition for the Planet: Environment and Health DOI Creative Commons
Gökçe Sueda Aydoğdu, Makbule Gezmen Karadağ

Current Nutrition Reports, Journal Year: 2025, Volume and Issue: 14(1)

Published: March 20, 2025

Abstract Purpose of Review Protecting the planet is protecting future. Food production systems are among most important human activities threatening planetary health. Diet, food systems, environment, and health interconnected. Accordingly, this review aims to assess effects nutrition on relationship between some types diets defined as sustainable Recent Findings Many have been proposed protect health, but there no consensus which diet best. It should not be forgotten that diets, plant-based vegetarian/vegan can reduce environmental pressure. Still, they cannot same effect in every country, these may different depending differences countries' income level, nutritional culture, systems. Moreover, it overlooked cause difficulties terms adaptation, deficiencies nutrients, suitable for all segments society. Sustainable such Mediterranean New Nordic, well Dietary Approaches Stop Hypertension, more flexible acceptable. Summary Instead a globally recommended reference each country analyze its choose appropriate methods style burden, improve create policies accordingly, help achieve goals faster.

Language: Английский

Citations

0

Adherence to the Eat-Lancet diet and its association with depression and anxiety among Iranian adults: a cross-sectional multicentric study DOI Creative Commons
Ghazaal Alavi Tabatabaei, Noushin Mohammadifard,

Fahimeh Haghighatdoost

et al.

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: March 27, 2025

Background Previous studies have shown a connection between diet and mental health. However, there is limited evidence on how emerging diets, particularly the EAT-Lancet reference (ELD), relate to depression anxiety. This study aims investigate potential impact of ELD adherence these health conditions. Methods materials cross-sectional recruited 1,970 Iranian adults using stratified multistage random cluster sampling method, part community-based investigation conducted in five cities from February 2018 July 2019. Participants’ regular dietary intake was assessed validated food frequency questionnaire. The formulated based consumption 14 components outlined ELD. Anxiety were evaluated version Hospital Scale. Results In fully adjusted model, no significant association depressive symptoms (aOR T3 vs. T1 = 0.89; 95% CI: 0.66, 1.19; p trend 0.42) anxiety 0.93; 0.70, 1.23; 0.62) whole population. analysis by sex, inverse found only among men 0.66; 0.40, 1.07; 0.047) but not women 0.71, 0.44, 1.15; 0.103). No observed either or women. Conclusion Despite null population, higher associated with lower risk males.

Language: Английский

Citations

0

Association between adherence to Eat‐Lancet diet and incidence and mortality of lung cancer: A prospective cohort study DOI Creative Commons
Yi Xiao, Linglong Peng,

Zhiquan Xu

et al.

Cancer Science, Journal Year: 2023, Volume and Issue: 114(11), P. 4433 - 4444

Published: Aug. 31, 2023

Previous research has shown that adhering to the Eat-Lancet diet (ELD) is associated with a lower risk of chronic diseases and mortality. However, associations between ELD lung cancer incidence mortality are unclear. To address this gap, we conducted prospective cohort study involving 101,755 adults from Prostate, Lung, Colorectal, Ovarian (PLCO) trial in USA. The score was utilized assess compliance ELD, higher scores indicating greater compliance. We employed Cox regression analyses calculate hazard ratios (HRs) 95% confidence intervals (CIs) its subtypes. In addition, sensitivity were performed ensure robustness our findings. total, 1706 cases 1217 cancer-associated deaths recorded during period. Our analysis revealed significantly reduced (HRQuartile 4 vs. Quartile 1 : 0.73; CI: 0.60, 0.89; ptrend = 0.001) 0.74; 0.59, 0.93; 0.005) dose-response manner (all pnonlinearity > 0.05). reliability these results supported by analyses. Notably, primarily observed non-small-cell cancer. conclusion, findings suggest adherence may be

Language: Английский

Citations

10

EAT‐Lancet Diet Pattern, Genetic Predisposition, Inflammatory Biomarkers, and Risk of Lung Cancer Incidence and Mortality DOI
Fubin Liu,

Changyu Si,

Linlin Chen

et al.

Molecular Nutrition & Food Research, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 5, 2024

Scope The association between a planetary and sustainable EAT‐Lancet diet lung cancer remains inconclusive, with limited exploration of the role genetic susceptibility inflammation. Methods results study includes 175 214 cancer‐free participants in UK Biobank. Fourteen food components are collected from 24‐h dietary recall questionnaire. A polygenic risk score is constructed through capturing overall variants for cancer. Sixteen inflammatory biomarkers assayed blood samples. Participants highest scores (≥12) have lower incidence (hazard ratio [HR] = 0.64, 95% confidence interval [CI]: 0.51–0.80) mortality (HR 0.65, CI: 0.48–0.88), compared to those lowest (≤8). Interestingly, there significantly protective trend against both adenocarcinoma squamous cell carcinoma higher scores. Despite no significant interactions, reduction observed increasing decreasing risk. Ten partially mediate Conclusion depicts conferred by associated inflammation levels among individuals diverse predispositions.

Language: Английский

Citations

3