Transient Stuttering as a Sole Presentation in a Patient With a Subcentimeter Left Frontal Cortical Ischemic Infarct DOI Open Access

Ethan Salter,

Sophia Salter,

William Im

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 15, 2024

Stuttering is a complex speech disorder that associated with variety of etiologies, including psychological factors, metabolic disorders, and structural abnormalities. While stuttering typically not caused by stroke, it important to include in the diagnostic evaluation, especially patients history neurological conditions. Of clinical presentations stroke-induced stuttering, transient following stroke has seldom been documented, as most who develop stutter end up developing permanent deficits. Additionally, cases are part broader presentation, generally does present an isolated symptom. Furthermore, although strokes various sizes have implicated quite uncommon for affected lesion be smaller than 1 cm. We rare case transient, subcentimeter subsequent review relevant literature. Our report highlights diversity stroke-related disorders importance considering even minor differential diagnosis stuttering.

Language: Английский

From Prodromal Stages to Clinical Trials: The Promise of Digital Speech Biomarkers in Parkinson's Disease DOI Creative Commons
Jan Rusz, Paul Krack, Elina Tripoliti

et al.

Neuroscience & Biobehavioral Reviews, Journal Year: 2024, Volume and Issue: 167, P. 105922 - 105922

Published: Oct. 18, 2024

Language: Английский

Citations

8
The application of Non-invasive Neuromodulation in Stuttering: Current Status and Future Directions DOI Creative Commons
Mehdi Bakhtiar, Karim Johari

Journal of Fluency Disorders, Journal Year: 2025, Volume and Issue: 83, P. 106100 - 106100

Published: Jan. 27, 2025

Language: Английский

Citations

0
The relationship between activities of daily living and speech impediments based on evidence from statistical and machine learning analyses DOI Creative Commons
Jun Liu, Hong-Guo Li, Y. J. Mao

et al.

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: Feb. 6, 2025

Speech impediments (SIs) are increasingly prevalent among middle-aged and older adults, raising concerns within public health. Early detection of potential SI in this demographic is critical. This study investigates the Activities Daily Living (ADL) as a predictive marker for SI, utilizing data from 2018 China Health Retirement Longitudinal Study (CHARLS), which includes 10,136 individuals aged 45 above. The Barthel Index (BI) was used to assess ADL, correlation between ADL examined through statistical analyses. Machine learning algorithms (Support Vector Machine, Decision Tree, Logistic Regression) were employed validate findings elucidate underlying relationship SI. poses significant challenges health quality life increasing demands on community-based home care services. In context global aging, it crucial investigate factors contributing While role biomarker remains unclear, aims provide new evidence supporting an early predictor analysis machine validation. Data derived CHARLS national baseline survey, comprising participants evaluated using BI, assessed based records "Speech impediments." Statistical analyses, including independent sample t-tests, chi-square tests, Pearson Spearman hierarchical multiple linear regression, conducted SPSS 25.0. algorithms, specifically Support (SVM), Tree (DT), Regression (LR), implemented Python 3.10.2. Analysis characteristics revealed that average BI score "With impediments" group 49.46, significantly lower than 85.11 "Without group. indicated negative (r = -0.205, p < 0.001). Hierarchical regression confirmed robustness across three models (B -0.001, β -0.168, t -16.16, 95% CI -0.001 0.000). validated findings, confirming accuracy with area under curve (AUC) scores SVM-AUC 0.648, DT-AUC 0.931, LR-AUC 0.666. inclusion improved overall performance, highlighting its positive impact prediction. various methodologies demonstrate finding further corroborated by algorithms. Impairment increases likelihood occurrence, underscoring importance maintaining populations mitigate risk

Language: Английский

Citations

0
Improving Stuttering Through Augmented Multisensory Feedback Stimulation DOI Creative Commons

Giovanni Muscarà,

Alessandra Vergallito,

Valentina Letorio

et al.

Brain Sciences, Journal Year: 2025, Volume and Issue: 15(3), P. 246 - 246

Published: Feb. 25, 2025

Background/Objectives: Stuttering is a speech disorder involving fluency disruptions like repetitions, prolongations, and blockages, often leading to emotional distress social withdrawal. Here, we present Augmented Multisensory Feedback Stimulation (AMFS), novel personalized intervention improve in people who stutter (PWS). AMFS includes five-day intensive phase aiming at acquiring new skills, plus reinforcement designed facilitate the transfer of these skills across different contexts their automatization into effortless behaviors. The concept our derives from prediction neurocomputational model Directions Velocities Articulators (DIVA). treatment applies dynamic multisensory stimulation disrupt PWS’ maladaptive over-reliance on sensory feedback mechanisms, promoting emergence participants’ natural voices. Methods: Forty-six PWS control group, including twenty-four non-stuttering individuals, participated this study. severity physiological measures, such as heart rate electromyographic activity, were recorded before after during stage but only once controls. Results: results showed significant reduction stuttering end phase, which was maintained training. Crucially, worse performance found than controls baseline not intervention. In PWS, signals activity training phases compared baseline. Conclusions: Our findings show that provides promising approach enhancing fluency. Future studies should clarify mechanisms underlying assess whether effects persist conclusion.

Language: Английский

Citations

0
Spike-phase coupling of subthalamic neurons to posterior perisylvian cortex predicts speech sound accuracy DOI Creative Commons
Matteo Vissani, Alan Bush, Witold Lipski

et al.

Nature Communications, Journal Year: 2025, Volume and Issue: 16(1)

Published: April 9, 2025

Speech provides a rich context for understanding how cortical interactions with the basal ganglia contribute to unique human behaviors, but opportunities direct intracranial recordings across cortical-basal networks are rare. Here we have recorded electrocorticographic signals in cortex synchronously single units during awake neurosurgeries where participants spoke syllable repetitions. We discovered that individual subthalamic nucleus (STN) neurons transient (200 ms) spike-phase coupling (SPC) events multiple regions. The spike timing of STN is locked phase theta-alpha oscillations supramarginal and posterior superior temporal gyrus speech planning production. sound errors occur when this STN-cortical interaction delayed. Our results suggest timely between perisylvian support auditory-motor coordinate transformation or phonological working memory planning. These findings establish framework other additionally indicate firing-rate based models insufficient explaining circuit behavior.

Language: Английский

Citations

0
Influences of speaking task demands on sensorimotor oscillations in adults who stutter: Implications for speech motor control DOI

Eric W. Brown,

Andrew Bowers,

M. Blake Rafferty

et al.

Clinical Neurophysiology, Journal Year: 2024, Volume and Issue: 169, P. 76 - 88

Published: Nov. 10, 2024

Language: Английский

Citations

3
Characterizing Drug-Induced Stuttering in Electronic Health Records DOI Creative Commons
Dillon G. Pruett, Christine Hunter, Alyssa Scartozzi

et al.

Journal of Communication Disorders, Journal Year: 2024, Volume and Issue: 113, P. 106475 - 106475

Published: Nov. 19, 2024

Language: Английский

Citations

1
Transient Stuttering as a Sole Presentation in a Patient With a Subcentimeter Left Frontal Cortical Ischemic Infarct DOI Open Access

Ethan Salter,

Sophia Salter,

William Im

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 15, 2024

Stuttering is a complex speech disorder that associated with variety of etiologies, including psychological factors, metabolic disorders, and structural abnormalities. While stuttering typically not caused by stroke, it important to include in the diagnostic evaluation, especially patients history neurological conditions. Of clinical presentations stroke-induced stuttering, transient following stroke has seldom been documented, as most who develop stutter end up developing permanent deficits. Additionally, cases are part broader presentation, generally does present an isolated symptom. Furthermore, although strokes various sizes have implicated quite uncommon for affected lesion be smaller than 1 cm. We rare case transient, subcentimeter subsequent review relevant literature. Our report highlights diversity stroke-related disorders importance considering even minor differential diagnosis stuttering.

Language: Английский

Citations

0