Neuro-Oncological Superiority of Supratotal Resection in Lower-Grade Gliomas DOI
Alberto L. Gallotti, Marco Rossi, Marco Conti Nibali

et al.

Neuro-Oncology, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 7, 2024

Supratotal-Resection (SpTR) is a promising surgical strategy in Lower-grade gliomas (LGGs). SpTR assessment, feasibility and distinctive features, as well clinical benefit at first second surgery on overall-survival must be better characterized. The critical percentage of resection exceeding FLAIR margins to obtain its impact long-term functional performance are also undefined.

Language: Английский

Long-term autonomy, professional activities, cognition, and overall survival after awake functional-based surgery in patients with IDH-mutant grade 2 gliomas: a retrospective cohort study DOI Creative Commons
Sam Ng, Valérie Rigau, Sylvie Moritz‐Gasser

et al.

The Lancet Regional Health - Europe, Journal Year: 2024, Volume and Issue: 46, P. 101078 - 101078

Published: Sept. 20, 2024

Language: Английский

Citations

9
Moving towards a connectomic view of neuro-oncology DOI
Hugues Duffau, Massimo Filippi

The Lancet Neurology, Journal Year: 2024, Volume and Issue: 23(7), P. 655 - 656

Published: June 13, 2024

Language: Английский

Citations

5
Neuroplasticity in Diffuse Low-grade Gliomas: Backward Modelling of Brain-tumor Interactions Prior to Diagnosis is Needed to Better Predict Recovery after Treatment DOI
Hugues Duffau

Current Neurology and Neuroscience Reports, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 9, 2025

Language: Английский

Citations

0
Mapping glioma’s impact on cognition: Insights from macrostructure, microstructure, and beyond DOI Creative Commons

Núria Cayuela,

Cristina Izquierdo, Lucía Vaquero

et al.

Neuro-Oncology Advances, Journal Year: 2025, Volume and Issue: 7(1)

Published: Jan. 1, 2025

Cognitive impairment (CI) significantly impacts the quality of life glioma patients. The main contributing risk factors include tumor characteristics, treatment-related factors, and their complex interplay. This review explores role advanced structural neuroimaging techniques in understanding CI A literature search was conducted PubMed, PsycINFO, ISI Web Knowledge using specific keywords. We included studies with magnetic resonance imaging objective neuropsychological exams. At diagnosis, during pre-surgery phase, associations between characteristics cognitive outcomes have been described. Specifically, patients isocitrate dehydrogenase (IDH)-wild-type gliomas exhibit more adverse outcomes, accompanied by disruptions gray (GM) white matter (WM) networks when compared to IDH-mutant. In addition, pre- post-surgery analyses highlight importance preserving WM tracts, such as inferior longitudinal arcuate fasciculus, mitigating verbal memory language processing decline. Furthermore, examining perisylvian regions emphasizes deleterious effects on various domains. Additionally, it has suggested that neuroplastic reorganization could serve a compensatory mechanism against CI. Lastly, limited number suggest long-term linked GM atrophy leukoencephalopathy induced radiotherapy ± chemotherapy survivors, highlighting need for improving treatment approaches, particularly extended survival expectations. underscores nuanced an individual approach management Neuroplastic insights offer clinicians valuable guidance surgical decision-making personalized therapeutic approaches thus patient neuro-oncology.

Language: Английский

Citations

0
The urgent need to redefine quality of life in patients with low-grade glioma DOI Creative Commons
Hugues Duffau

ESMO rare cancers., Journal Year: 2025, Volume and Issue: unknown, P. 100003 - 100003

Published: Feb. 1, 2025

Language: Английский

Citations

0
The capability to successfully study and to be graduated in students who underwent awake surgical resection for a low-grade glioma DOI
Hugues Duffau

Journal of Neuro-Oncology, Journal Year: 2025, Volume and Issue: unknown

Published: April 17, 2025

Language: Английский

Citations

0
Neuro-Oncological Superiority of Supratotal Resection in Lower-Grade Gliomas DOI
Alberto L. Gallotti, Marco Rossi, Marco Conti Nibali

et al.

Neuro-Oncology, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 7, 2024

Supratotal-Resection (SpTR) is a promising surgical strategy in Lower-grade gliomas (LGGs). SpTR assessment, feasibility and distinctive features, as well clinical benefit at first second surgery on overall-survival must be better characterized. The critical percentage of resection exceeding FLAIR margins to obtain its impact long-term functional performance are also undefined.

Language: Английский

Citations

0