New data allow to better understand the secrets of lipoprotein(a): is that for sure?

European Heart Journal Open, Journal Year: 2024, Volume and Issue: 4(5)

Published: Aug. 3, 2024

Language: Английский

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Progress of angiographic cardiac allograft vasculopathy in long-term transplanted patients: Longitudinal evaluation of its association with dyslipidemia patterns

The American Journal of Cardiology, Journal Year: 2024, Volume and Issue: 238, P. 47 - 54

Published: Nov. 28, 2024

Language: Английский

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Lipoprotein(a) distribution in hospitalised Asian patients with ischaemic heart disease

Therapeutic Advances in Cardiovascular Disease, Journal Year: 2024, Volume and Issue: 18

Published: Jan. 1, 2024

Background: Elevated lipoprotein(a) [Lp(a)] is a common hyperlipidaemic condition with strong genetic predisposition and independently associated ischaemic heart disease (IHD). A Mendelian randomisation study has suggested that elevated Lp(a) likely to confer similar causal risks as heterozygous familial hypercholesterolemia for premature IHD. We aimed characterise the clinical profiles of admitted patients IHD at least one measurement. also investigated whether concentration was onset Methods: This descriptive, non-interventional, retrospective data from single tertiary hospital cohort in Singapore, which consecutively recruited 521 hospital. Results: total 82.2% were men, 46.6% had newly diagnosed 10% The median levels 35.2 nmol/L. 70.8% normal concentrations (<70 nmol/L), 13.4% people ⩾ 70 <120 nmol/L 15.7% 120 distribution positively skewed right all ethnicities. Patients Indian ethnicity female gender higher compared other ethnicities gender, respectively. Multivariable regression analysis identified 155 mmol/L be development (OR = 2.90, 95% CI: 1.26–6.67, p 0.012). Conclusion: There exist differences across gender. subgroup suggests

Language: Английский

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Lipoprotein(a): Ein „übersehener“ Risikofaktor

Trillium Diagnostik, Journal Year: 2024, Volume and Issue: 22(4), P. 252 - 255

Published: Dec. 13, 2024

In den vergangenen Jahrzehnten hat die klinische Forschung gezeigt, dass Lipoprotein(a) ein bedeutender Risikofaktor für Entwicklung kardiovaskulärer Erkrankungen wie der koronaren Herzkrankheit und von Atherosklerose ist. Während Zusammenhang erhöhten Low-Density-Lipoprotein-Spiegeln mit Herz-Kreislauf-Erkrankungen allgemein anerkannt ist, rückt zunehmend in Fokus medizinischen Betrachtung. diesem wurden genetischen metabolischen Eigenschaften sowie sein Einfluss auf Parameter intensiv untersucht. Der vorliegende Text befasst sich zentralen Aspekten Lipoprotein(a), seiner Bedeutung Epidemiologie, Genetik dem Lipoproteinstoffwechsel seinem Herz-Kreislauf-Erkrankungen.

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Intervention, improved prevention, imaging, inflammation, and innovation: the five I's cardiovascular highlights in EHJ Open 2024

European Heart Journal Open, Journal Year: 2024, Volume and Issue: 5(1)

Published: Dec. 24, 2024

Language: Английский

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