The complex relationship between cyanobacteria and antibiotics/antimicrobial resistance in the environment: an emerging factor in the One Health vision on antimicrobial resistance

Advances in Oceanography and Limnology, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 16, 2025

In 2015, the World Health Organization (WHO) declared Antimicrobial Resistance (AMR) as one of most critical health issues. It proposed, with Food and Agriculture (FAO) OIE (World for Animal Health), to address this by a One approach, recognizing connection between humans, animals, environmental health. Currently, hypothesis is developing that cyanobacteria cyanotoxins may contribute AMR in water. Recent research appears suggest: i) an impact on antibiotic-resistance gene transfer bacteria; ii) role reservoir AMR. Finally, cyanotoxin production be stimulated exposure antibiotics. These findings strengthen importance considering environment its complexity.

Language: Английский

Taxonomic and functional metagenomic assessment of a dolichospermum bloom in a large and deep lake south of the Alps

FEMS Microbiology Ecology, Journal Year: 2024, Volume and Issue: 100(10)

Published: Sept. 3, 2024

Abstract Untargeted genetic approaches can be used to explore the high metabolic versatility of cyanobacteria. In this context, a comprehensive metagenomic shotgun analysis was performed on population Dolichospermum lemmermannii collected during surface bloom in Lake Garda summer 2020. Using phylogenomic approach, almost complete metagenome-assembled genome obtained from allowed clarify taxonomic position species within genus and contributed frame taxonomy ADA group (Anabaena/Dolichospermum/Aphanizomenon). addition common functional traits represented central metabolism photosynthetic cyanobacteria, annotation uncovered some distinctive adaptive that helped define factors promote maintain bloom-forming heterocytous nitrogen-fixing Nostocales oligotrophic lakes. addition, clusters were identified potentially encode several secondary metabolites previously unknown populations evolving southern Alpine district. These included geosmin, anabaenopetins, other bioactive compounds. The results expanded knowledge competitive drive algal blooms provided guidance for more targeted analyses cyanobacterial with implications human health water resource use.

Language: Английский

Metagenomic profiling of cecal microbiota and antibiotic resistome in rodents

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 286, P. 117186 - 117186

Published: Oct. 19, 2024

Language: Английский