Population Structure of the Invasive Asian Tiger Mosquito, Aedes albopictus, in Europe

Ecology and Evolution, Journal Year: 2025, Volume and Issue: 15(3)

Published: March 1, 2025

The Asian tiger mosquito, Aedes albopictus, is currently the most widespread invasive mosquito species in world. It poses a significant threat to human health, as it vector for several arboviruses. We used SNP chip genotype 748 Ae. albopictus mosquitoes from 41 localities across Europe, 28 native range Asia, and 4 Americas. Using multiple algorithms, we examined population genetic structure differentiation within Europe our global dataset gain insight into origin of European populations. also compared results data those obtained using genotypes 11 microsatellite loci (N = 637 25 localities) explore how sampling effort type marker may influence conclusions about structure. While some analyses detected more than 20 clusters worldwide, found could be grouped 7 distinct clusters, with populations originating East Asia (Japan or China). Interestingly, Eastern did not share ancestry any Americas, indicating that these originated areas sampled this study. datasets similar patterns but detect subtle revealed SNPs. Overall, offered higher resolution detecting potential origins invasions.

Language: Английский

Population genetic analysis of Aedes aegypti reveals evidence of emerging admixture populations in coastal Kenya

PLoS neglected tropical diseases, Journal Year: 2025, Volume and Issue: 19(5), P. e0013041 - e0013041

Published: May 20, 2025

Background The Aedes aegypti mosquito is widespread in tropical and subtropical regions. There are two recognized subspecies; the invasive ( Aaa ) ancestral formosus Aaf ). common throughout Kenya whereas , which was historically confined to coastal regions, has undergone a range expansion. In areas of sympatry, gene flow may lead admixed populations with potential differences vectorial capacity. We hypothesize that Ae. have higher proportion ancestry than those from inland locations Kenya, influenced by their distance coast. Methodology Adult mosquitoes were collected using Biogent (BG) sentinel traps baited carbon-dioxide (CO 2 cities towns along Kenyan northern transport corridor. population structure, genetic diversity, isolation analyzed genome-wide single nucleotide polymorphism (SNPs) datasets generated an microarray chip targeting ≈50,000 SNPs. placed into global context within phylogenetic tree, combining dataset previously published database database. Results A total 67 genotyped, we found western constitute genetically homogenous clusters African showed evidence admixture between subspecies. positive correlation (Observation = 0.869, p 0.0023) (FST) geographic distance, suggesting distance. analysis structure suggest Asian source invasion . Conclusions These results provide emerging sylvatic domesticated-human preferring observed positively influence capacity, potentially increasing human feeding preference, biting rates vector competence could be promoting dengue chikungunya outbreaks.

Language: Английский

Sequencing 1206 genomes reveals origin and movement ofAedes aegyptidriving increased dengue risk

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: July 24, 2024

Abstract The number of dengue cases worldwide has increased ten-fold over the past decade as Aedes aegypti , primary vector this disease, thrives and expands its distribution, revealing limitations to current control methods. To better understand how Ae. evolved from a forest dwelling, generalist species highly anthropophilic urban impact contemporary gene flow on future control, we sequenced 1,206 genomes mosquitoes collected at 74 locations around globe. Here show that after evolving preference for humans in Sahel region West Africa, origin fully domesticated, subspecies ( Aaa ) occurred Americas during Atlantic Slave Trade era was followed by explosive expansion In recent decades, invaded coastal ancestral home range, introducing insecticide resistance mutations an affinity human hosts. Evidence back-to-Africa migration is found regions with outbreaks, raising concern global movement could increase transmission risk arboviruses including Africa. These data provide platform further study important mosquito underscore developing complexity fight limit spread dengue, Zika, chikungunya diseases.

Language: Английский