From the cauldron of conflict: Endogenous gene regulation by piRNA and other modes of adaptation enabled by selfish transposable elements DOI Creative Commons
Justin P. Blumenstiel

Seminars in Cell and Developmental Biology, Journal Year: 2024, Volume and Issue: 164, P. 1 - 12

Published: May 31, 2024

Transposable elements (TEs) provide a prime example of genetic conflict because they can proliferate in genomes and populations even if harm the host. However, numerous studies have shown that TEs, though typically harmful, also fuel for adaptation. This is code functional sequences be useful host which reside. In this review, I summarize "how" "why" adaptation enabled by between TEs hosts. addition, focusing on mechanisms TE control small piwi-interacting RNAs (piRNAs), highlight an indirect form conflict. case, defense regulate been redeployed endogenous gene regulation. propose released meiosis early eukaryotes may important because, among other reasons, it spurred evolutionary innovation multiple interwoven trajectories - part hosts embedded parasites. evolution function as complexity generating engine was critical player eukaryotic evolution.

Language: Английский

Advances in Cellular and Molecular Biology Assays: A Review of Gold Standard Methods DOI

Katiana Simões Lopes Kittelson,

Allana Cristina Faustino Martins,

Gizele Celante

et al.

Published: April 30, 2025

Considering the number of available methods in molecular and cellular biology rapid development new technologies, need for an updated guide on what is currently applied how to choose best method a specific goal has increased. Gold standard are known their accuracy reliable data under certain circumstances, allowing replicability. This perspective aims characterize define current gold techniques from last five years, enlighten historical background, cite drawbacks benefits, delimit possible future aspects.

Language: Английский

Citations

0
From the cauldron of conflict: Endogenous gene regulation by piRNA and other modes of adaptation enabled by selfish transposable elements DOI Creative Commons
Justin P. Blumenstiel

Seminars in Cell and Developmental Biology, Journal Year: 2024, Volume and Issue: 164, P. 1 - 12

Published: May 31, 2024

Transposable elements (TEs) provide a prime example of genetic conflict because they can proliferate in genomes and populations even if harm the host. However, numerous studies have shown that TEs, though typically harmful, also fuel for adaptation. This is code functional sequences be useful host which reside. In this review, I summarize "how" "why" adaptation enabled by between TEs hosts. addition, focusing on mechanisms TE control small piwi-interacting RNAs (piRNAs), highlight an indirect form conflict. case, defense regulate been redeployed endogenous gene regulation. propose released meiosis early eukaryotes may important because, among other reasons, it spurred evolutionary innovation multiple interwoven trajectories - part hosts embedded parasites. evolution function as complexity generating engine was critical player eukaryotic evolution.

Language: Английский

Citations

3