The E3 ubiquitin ligase BRG3 and the protein kinase MPK7 antagonistically regulate LBD36 turnover, a key node for integrating nitrate and gibberellin signaling in apple DOI Open Access

Xin‐Long Guo,

Da‐Ru Wang, Baoyou Liu

et al.

New Phytologist, Journal Year: 2025, Volume and Issue: unknown

Published: March 14, 2025

Summary Nitrate is the main source of nitrogen in plants. stimulation causes changes plant secondary metabolites, including anthocyanins. However, molecular mechanism underlying how nitrate regulates anthocyanin biosynthesis remains unclear. In this study, we identified a response factor MdLBD36 apple. This positively regulated deficiency‐induced by promoting transcriptional activity MdABI5, an important regulator anthocyanins, and directly activated MdABI5 expression. The E3 ubiquitin ligase MdBRG3 promoted ubiquitinated degradation to reduce under nitrate‐sufficient conditions. deficiency‐activated MdMPK7 maintained stimulating effect on counteracting MdBRG3‐mediated MdLBD36. coordinated gibberellin (GA) signaling regulate biosynthesis. GA repressor MdRGL2a contributed MdLBD36‐promoted enhancing MdLBD36–MdABI5 interaction increasing activation . summary, our results elucidate framework regulation ubiquitination phosphorylation. study revealed cross talk between provides references for in‐depth exploration signal transduction pathway its interactions with hormones.

Language: Английский

Research Progress in the Regulation of the ABA Signaling Pathway by E3 Ubiquitin Ligases in Plants DOI Open Access

Hongyun Kou,

Xiaopei Zhang,

Jinghao Jia

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(13), P. 7120 - 7120

Published: June 28, 2024

E3 ubiquitin ligases (UBLs), as enzymes capable of specifically recognizing target proteins in the process protein ubiquitination, play crucial roles regulating responses to abiotic stresses such drought, salt, and temperature. Abscisic acid (ABA), a plant endogenous hormone, is essential growth, development, disease resistance, defense against stresses, acts through complex ABA signaling pathway. Hormone transduction relies on regulation, important parts Therefore, this paper reviews ubiquitin–proteasome-mediated degradation pathway, ABA-related pathways, regulation ABA-signaling-pathway-related genes by ligases, aiming provide references for further exploration relevant research how regulate

Language: Английский

Citations

4
Synergistic impact of MdERF2 and MdPUB17 on the biosynthesis of wax in apple epidermis DOI Creative Commons

Meng Lv,

Xinhua Zhang, Jin Shang

et al.

Horticultural Plant Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

0
Exploring ABI5 regulation: Post‐translational control and cofactor interactions in ABA signaling DOI Open Access
Chang Du,

Haiyan Bai,

Yujie Yan

et al.

The Plant Journal, Journal Year: 2025, Volume and Issue: 121(3)

Published: Feb. 1, 2025

SUMMARY Abscisic acid insensitive 5 (ABI5) is a pivotal transcription factor in abscisic (ABA) signaling, playing an essential role plant growth and responses to abiotic stress. This key regulator subject multifaceted regulation, especially on post‐translational mechanisms. Recent research has shed light the regulation of ABI5, encompassing both modifications (PTMs) modulation its transcriptional activity. In this review, we provide comprehensive overview current knowledge surrounding along with influence various cofactors activity protein stability. The potential biological roles PTMs ABI5 context ABA signaling stress are also explored. As one most extensively studied proteins environmental responses, sophisticated precise understanding regulatory mechanisms that govern not only beneficial for application genetic engineering but helpful our exploration fundamental principles regulation.

Language: Английский

Citations

0
The E3 ubiquitin ligase BRG3 and the protein kinase MPK7 antagonistically regulate LBD36 turnover, a key node for integrating nitrate and gibberellin signaling in apple DOI Open Access

Xin‐Long Guo,

Da‐Ru Wang, Baoyou Liu

et al.

New Phytologist, Journal Year: 2025, Volume and Issue: unknown

Published: March 14, 2025

Summary Nitrate is the main source of nitrogen in plants. stimulation causes changes plant secondary metabolites, including anthocyanins. However, molecular mechanism underlying how nitrate regulates anthocyanin biosynthesis remains unclear. In this study, we identified a response factor MdLBD36 apple. This positively regulated deficiency‐induced by promoting transcriptional activity MdABI5, an important regulator anthocyanins, and directly activated MdABI5 expression. The E3 ubiquitin ligase MdBRG3 promoted ubiquitinated degradation to reduce under nitrate‐sufficient conditions. deficiency‐activated MdMPK7 maintained stimulating effect on counteracting MdBRG3‐mediated MdLBD36. coordinated gibberellin (GA) signaling regulate biosynthesis. GA repressor MdRGL2a contributed MdLBD36‐promoted enhancing MdLBD36–MdABI5 interaction increasing activation . summary, our results elucidate framework regulation ubiquitination phosphorylation. study revealed cross talk between provides references for in‐depth exploration signal transduction pathway its interactions with hormones.

Language: Английский

Citations

0