Hormonal profile features in patients with infertility against the background of uterine leiomyoma and chronic endometritis DOI Open Access
S. V. Khmil, N.Ya. Petryshyn

Bukovinian Medical Herald, Journal Year: 2023, Volume and Issue: 27(3 (107)), P. 69 - 74

Published: Sept. 28, 2023

The аim of research is to study the hormonal profile peculiarities women with infertility against background uterine leiomyoma and chronic endometritis unsuccessful IVF attempts in anamnesis.Material Methods. A retrospective analysis outpatient medical cards 130 patients was carried out. Patients were divided into three clinical groups. first group consisted 47 leiomyoma, second one included 53 (patients this also had failed anamnesis). third (control) 30 female due male factor. concentration levels main gonadotropic sex hormones blood serum studied compared on different days menstrual cycle.Results. Certain changes profile, including basal reproductive system their cycle, revealed among groups control group.Conclusions. features are primarily related presence or another concomitant gynecological pathology, combined course. This definitely probably has an impact further results treatment ART.

Language: Английский

Cine-MRI for Quantifying Uterine Peristalsis: A Systematic Review and Meta-Analysis DOI Open Access
Àngela Vidal,

Christene Bora,

Jeannette von Holzen

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(3), P. 1021 - 1021

Published: Feb. 6, 2025

Background: Uterine contractility, also known as uterine peristalsis (UP), is a critical determinant of fertility, affecting sperm transport and embryo implantation. Increased peristaltic activity has been associated with reduced pregnancy rates. However, data are heterogeneous contractility not widely translated into clinical practice. Cine-MRI, although limited by cost heterogeneity in reporting, emerged promising tool to assess dynamics increase our knowledge UP physiological pathological conditions. Objective: This systematic review meta-analysis aimed describe patterns conditions, including endometriosis fibroids, using cine-MRI. Methods: A literature search the Medline, Embase, Cochrane CENTRAL databases Google Scholar was conducted up May 2024, studies evaluating Clinical were included, excluding those affected therapeutic interventions or unrelated pathologies. pooled from comparing patients endometriosis. Results: In 13 included (365 women), varied significantly according menstrual cycle phases showed that women had higher luteal phase (0.74; 95% CI: 0.27–1.21) but periovulatory (SMD 0.8; −3.78–5.37). Conclusions: Cine-MRI diagnostic for analysis UP. Endometriosis impaired UP, which may be cause decreased implantation rate infertility further research needed consolidate effect on fertility develop standardised cost-effective tools tailor treatment.

Language: Английский

Citations

2

Uterine fibroid–related infertility: mechanisms and management DOI
Jacques Donnez, Hugh S. Taylor, Louis Marcellin

et al.

Fertility and Sterility, Journal Year: 2024, Volume and Issue: 122(1), P. 31 - 39

Published: March 5, 2024

Language: Английский

Citations

10

Female sexual response among Flo app users in the United States DOI Creative Commons
Frederick G. B. Goddard, Jasmin Mahabamunuge, Adam C. Cunningham

et al.

npj Women s Health, Journal Year: 2025, Volume and Issue: 3(1)

Published: Jan. 8, 2025

Female sexual response has historically been understudied. Using the female function index (FSFI-6), this study estimated and its associations with sociodemographic characteristics, self-reported health conditions, logging of sex events. Participants included a large demographically diverse sample 2392 users Flo Health mobile application (app) in United States. scored higher on FSFI-6, suggesting function, if they were actively trying to conceive, met criteria for obesity (body mass (BMI) ≥ 30 kg/m2), or engaged higher-than-average in-app event logging. Conversely, being underweight (BMI < 18.5 reporting at least one queried was associated lower FSFI-6 scores. This demonstrates that many individual factors are relevant is first report positive association between obesity, function.

Language: Английский

Citations

0

The feasibility of high-resolution organ-axial T2-weighted MRI when combined with federation of gynecology and obstetrics (FIGO) classification of uterine fibroid patients DOI Creative Commons
Xiaoyi Liu, Ke Wang,

Xinyi Gou

et al.

Abdominal Radiology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 11, 2025

Correctly classifying uterine fibroids is essential for treatment planning. The objective of this study was to assess the accuracy and reliability FIGO classification system in categorizing via organ-axial T2WI further investigate factors associated with compression. A total 130 patients ultrasound-confirmed were prospectively enrolled between March 2023 May 2024. These underwent MR examinations, including body-axial T2W (sagittal axial) (high resolution oblique coronal double axial). For postprocessing, interobserver agreements two radiologists interagreements examinations operational descriptions evaluated kappa statistics. axial assessments compared when surgical outcomes used as gold standard. Kruskal‒Wallis test compare differences cavity deformation across various classifications. Spearman's rank correlation analyze parameters deformation. In total, 170 from included. Compared T2WI, showed better agreement greater descriptions, values 0.877 (P = 0.04) 0.932 0.037), respectively. assessment determining than that assessment, an 92.9% < 0.01). Thirty-two (38.1%) according types 0–7 2–5. Among these factors, size (S), base width (B), depth compression (D), D/B, D/S, angle (A) significantly differed among different 0.05). Compression exhibited a linear type 0.001). provides on basis classification, which more consistent outcomes. Given excellent preoperative can contribute

Language: Английский

Citations

0

Assessment of Ovarian Reserve Parameters in Women Undergoing Uterine Fibroids Treatment with Hifu and Laparoscopic Myomectomy DOI

Lisha Tang,

Wang Mei,

Qing Zhu

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0

Identifying Shared Molecular Landscape between Uterine Fibroids and Recurrent Implantation Failure: An Integrated Bioinformatics Study DOI Creative Commons
Maryamsadat Hosseini, Basireh Bahrami, Mohammad Reza Zare

et al.

Heliyon, Journal Year: 2025, Volume and Issue: unknown, P. e43006 - e43006

Published: Feb. 1, 2025

Language: Английский

Citations

0

Influence of uterine fibroid on uterine blood flow, menstrual function and features of reproductive health disorders in women DOI Creative Commons

Z. S. Huseynova

Yakut Medical Journal, Journal Year: 2025, Volume and Issue: 1, P. 20 - 23

Published: March 17, 2025

The study was conducted on women aged 18-45 years old with uterine fibroids and impaired reproductive function. In patients fibroids, menarche began at an earlier age abnormal bleeding more often observed, causing posthemorrhagic anemia. Reproductive function disorders were caused by infertility miscarriages. Indicators of S/D, RI, PI the artery in presence lower than group healthy women. Primary predominated isolated myoma, myomatous nodes association benign diseases uterus secondary prevailed. Thus, timely assessment clinical symptoms early diagnosis myoma are important for pathological treatment to improve quality life restore

Language: Английский

Citations

0

The integrative health status of women with uterine fibroids wishing to maintain fertility: a cross-sectional study based on Levine’s conservation model DOI

Hye Moon Kim,

ChaeWeon Chung

Women s Health Nursing, Journal Year: 2025, Volume and Issue: 31(1), P. 9 - 21

Published: March 28, 2025

Purpose: The increasing incidence of uterine fibroids (UFs) among women who could consider conception presents challenges. This study examined the relationships fatigue, UF symptom severity, sexual function, anxiety, and loneliness across diverse life conditions treatment stages in with UFs wishing to maintain fertility.Methods: descriptive correlational study, guided by Levine’s conservation model, included 221 hoping their reproductive potential. Participants were recruited from gynecology-focused online communities, data collected through an survey. questionnaire gathered information on general treatment-related characteristics, as well measures loneliness. analyzed using statistics, independent t-test, one-way analysis variance, Welch test, Pearson correlation analysis.Results: Most participants (91.9%) experienced dysfunction was prevalent (85.5%). Fatigue, levels significantly intercorrelated (p≤.001), whereas severity only associated fatigue (r=.51, p<.001) function (r=–.41, p<.001). Women without specific pregnancy plans exhibited greater anxiety poorer than those plans, low economic status showed outcomes for most variables. currently undergoing medical reported highest while a longer diagnosis history or not receiving loneliness.Conclusion: intending fertility face multidimensional interrelated health Beyond fibroid-focused treatments, clinical nursing education should integrate physical psychosocial indicators supporting health.

Language: Английский

Citations

0

Addressing Cervical Stenosis and Uterine Fibroids in IVF: A Case Study on the Effectiveness of TMET DOI Creative Commons
Shradha Ulhe,

Namrata Choudhary,

Akash More

et al.

Journal of Pharmacy And Bioallied Sciences, Journal Year: 2025, Volume and Issue: unknown

Published: April 17, 2025

A BSTRACT This case study presents a 38-year-old female with history of infertility complicated by severe cervical stenosis and intramural fibroids, which rendered traditional transcervical embryo transfer (ET) ineffective. After previously failed cycles in vitro fertilization, the couple was advised for transmyometrial (TMET), an invasive technique that places straight into lining endometrium rather than through cervix. Full assessment showed appropriate hormone levels normospermia excluding presence male factor infertility. The patient received ovarian stimulation, oocyte retrieval, ET TMET. procedure, progesterone supplementations were given to sustain luteal phase. beta hCG test returned positive result after 2 weeks confirming pregnancy. illustrates effectiveness TMET avoiding anatomical issues associated conventional reinforces concept need customized fertility care.

Language: Английский

Citations

0

Impact of fibroids on fertility, pregnancy loss, and preconception management DOI

O. Ezike,

R Schneyer, Kelly N. Wright

et al.

Current Opinion in Obstetrics & Gynecology, Journal Year: 2025, Volume and Issue: unknown

Published: April 29, 2025

Purpose of review Although fibroids are understood to be a predominantly benign and common pathology, they can have significant impacts on patients’ quality life reproductive health. This summarizes the impact uterine fertility spontaneous abortion, while also addressing how treatment for affect fertility. Lastly, will address strategies preconception management optimize Recent findings The data regarding pregnancy loss is evolving. However, it agreed that determined by their location in uterus. Fibroids located submucosal layer or otherwise disrupting endometrial cavity impede implantation an embryo potentially increase risk abortion. When treating purpose fertility, surgical preferred over medication management. There limited supporting procedures such as artery embolization radiofrequency ablation improve Surgical not impacting remains controversial. Summary Uterine detrimental therefore require purposeful attention both diagnosis condition reproductive-aged women. alone Regardless, fibroid size should cataloged, offered patients experiencing difficulties with conception.

Language: Английский

Citations

0