Clinical application of a simplified hysteroscopic LNG-IUD non-suture fixation in the treatment of adenomyosis DOI Creative Commons
Y. L. Yu, Qing Cong, Long Sui

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 16, 2024

Abstract Background Placement of a levonorgestrel-releasing intrauterine device (LNG-IUD) is an effective treatment forpatients diagnosed with adenomyosis who had strong desire to preserve the uterus and no immediate fertility requirements. However, there are also some limitations suitability LNG-IUD for women adenomyosis, as causes distortion or enlargement uterine cavity. Therefore, more prone expulsion in patients adenomyosis. In this study, we aimed show original simplified approach using hysteroscope non-suture fixation Methods retrospectivecase series approved by Ethics Committee Obstetrics Gynecology Hospital Fudan University, sixty-two requirements short term were included study. They underwent hysteroscopic fixation LNG-IUD. All one-year postoperative follow-up evaluate rate, efficacy side effects. Results Sixty-two during long-term follow-up, every patient experienced complete remission their symptoms: significant decrease menstrual flow, relief dysmenorrhea, improvement quality life. Only two at 6 months 10 postoperatively, respectively. Conclusions Hysteroscopic can be minimally invasive alternative history expulsion. The method greatly reduces complexity performed efficiently office.

Language: Английский

Potential anatomical determinants of retrograde menstruation: a comprehensive narrative review DOI
Paolo Vercellini, Martina Piccini, Francesca Caprara

et al.

Reproductive BioMedicine Online, Journal Year: 2024, Volume and Issue: 49(4), P. 104345 - 104345

Published: June 21, 2024

Language: Английский

Citations

2
Adenomyosis: An Update Concerning Diagnosis, Treatment, and Fertility DOI Open Access
Aikaterini Selntigia, Pietro Molinaro, Silvio Tartaglia

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(17), P. 5224 - 5224

Published: Sept. 3, 2024

This review article aims to summarize current tools used in the diagnosis of adenomyosis with relative pharmacological and surgical treatment clarify association between infertility, considering importance an accurate this heterogeneous disease. Among different reported concepts, direction invagination gland cells from basalis endometrium deep into myometrium is most widely accepted opinion on development adenomyosis. Adenomyosis has been increasingly identified young women pain, AUB, or no symptoms by using imaging techniques such as transvaginal ultrasound magnetic resonance. Furthermore, often coexists other gynecological conditions, endometriosis uterine fibroids, increasing heterogeneity available data. However, there agreement definition classification adenomyotic lesions both histopathology points view, remains difficult unclear. A standard, universally system needs be implemented improve our understanding inform precise type could key designing RCT studies evaluating impact quality life terms menstrual symptoms, fertility, pregnancy outcome, given high risk miscarriage obstetric complications.

Language: Английский

Citations

2
The first Lugano workshop on the role of adenomyosis in ART DOI

Mauro Cozzolino,

Serdar E. Bulun, Dominique de Ziegler

et al.

Reproductive BioMedicine Online, Journal Year: 2024, Volume and Issue: 50(1), P. 104444 - 104444

Published: Sept. 13, 2024

Language: Английский

Citations

2
Inflammatory Bowel Disease and Endometriosis: Diagnosis and Clinical Characteristics DOI Creative Commons

Mariasofia Fiorillo,

Benedetto Neri, Roberto Mancone

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 12(11), P. 2521 - 2521

Published: Nov. 4, 2024

Endometriosis and inflammatory bowel disease (IBD) share some epidemiological, clinical pathogenetic features. A differential diagnosis between pelvic endometriosis IBD may be challenging, even for expert clinicians. In the present review, we aimed to summarize currently available data regarding relationship their possible association.

Language: Английский

Citations

2
Endometriosis risk is associated with shorter anogenital distance by meta-analysis DOI Creative Commons
Bernard J. Crespi

Journal of Endometriosis and Uterine Disorders, Journal Year: 2024, Volume and Issue: 8, P. 100083 - 100083

Published: May 23, 2024

Anogenital distance is a well-validated marker of prenatal testosterone, with shorter distances indicating lower levels during early gestation. A suite studies has tested for links anogenital risk endometriosis, but the findings are variable, leading to uncertainty in interpretation. This study was conducted provide an overall statistical assessment whether altered women compared controls. systematic review and meta-analysis were on association endometriosis distance. Three databases queried identification phase, random-effects applied data that met inclusion criteria. Meta-analysis showed AF, measured from anus posterior fourchette, significantly associated higher meta-analysis. By contrast, AC, clitoral surface, non-significant. Both analyses demonstrated significant heterogeneity across studies. Too few available robust investigation publication bias. The short provides support hypothesis represents, part, disorder mediated by relatively low testosterone development. conclusion implications understanding causes treatment endometriosis.

Language: Английский

Citations

2
European Union underinvestment in endometriosis research DOI Creative Commons
Paola Viganò, Maíra Casalechi, Marie‐Madeleine Dolmans

et al.

Journal of Endometriosis and Uterine Disorders, Journal Year: 2023, Volume and Issue: 5, P. 100058 - 100058

Published: Dec. 29, 2023

Endometriosis is considered one of the conditions that receives disproportionately low research funding relative to its burden. However, volume provided by European Commission (EC) for this disease in last decades poorly known among researchers and policymakers. This study aimed estimate commitment endometriosis Union (EU) over years. Research projects dedicated or partially related were identified COmmunity Development Information Service (CORDIS) database inventories EU projects. From database, we extracted all items using keyword "endometriosis" from inception 2023. retrieved classified three groups according level specific field. Of 145,983 overall fields CORDIS, n = 27 found be endometriosis, which 10 endometriosis-specific 7 endometriosis. The received funds about 15 million euros. specifically 4 identify candidate diagnostic biomarkers associated with 3 had a broader approach focused on both improvement therapeutic measures disease. Considering economic societal burden incurred investments has been so far limited. funded mainly diagnosis while few etiopathogenesis treatment.

Language: Английский

Citations

5
Prediction of venous thromboembolism in average-risk, young candidates for oral contraceptive use: to genotype, or not to genotype, that is the question DOI Open Access
Paolo Vercellini, Andrea Artoni, Maria Abbattista

et al.

American Journal of Obstetrics and Gynecology, Journal Year: 2024, Volume and Issue: 231(2), P. e78 - e79

Published: May 1, 2024

Language: Английский

Citations

1
Artificial Intelligence in the Management of Women with Endometriosis and Adenomyosis: Can Machines Ever Be Worse Than Humans? DOI Open Access
Giulia Emily Cetera, Alberto Eugenio Tozzi, Valentina Chiappa

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(10), P. 2950 - 2950

Published: May 16, 2024

Artificial intelligence (AI) is experiencing advances and integration in all medical specializations, this creates excitement but also concerns. This narrative review aims to critically assess the state of art AI field endometriosis adenomyosis. By enabling automation, may speed up some routine tasks, decreasing gynecologists' risk burnout, as well them spend more time interacting with their patients, increasing efficiency patients' perception being taken care of. Surgery benefit from AI, especially through its robotic surgery systems. improve detection anatomical structures enhance surgical outcomes by combining intra-operative findings pre-operative imaging. Not only that, promises quality facilitating clinical research. Through introduction decision-support tools, it can diagnostic assessment; predict treatment effectiveness side effects, reproductive prognosis cancer risk. However, concerns exist regarding fact that good data used tool development compliance sharing guidelines are crucial. Also, professionals worried render certain specialists obsolete. said, likely become a well-liked team member rather than usurper.

Language: Английский

Citations

1
Menstrual Disorders in Adolescence: Diagnostic and Therapeutic Challenges DOI Open Access

Christiane Anthon,

M Steinmann, Àngela Vidal

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(24), P. 7668 - 7668

Published: Dec. 16, 2024

Background: Adolescence is the period of life between ages 10 and 19. This essentially dominated by puberty. The first menstruation, called menarche, occurs, on average, at age 12–13. after especially 2 years, characterized anovulatory cycles, which can be accompanied menstrual irregularities. review aims to describe current status diagnostic therapeutic challenges physiological pathological causes irregularities in adolescence evaluates benefits from interdisciplinary collaboration ensure optimal care. Methods: A systematic literature search was conducted PubMed database April 2024 using following term: “menstrual disorder adolescence”. total 1724 abstracts were screened, relevant articles last years included. In addition, a supplementary topic-relevant guidelines European Society Human Reproduction Embryology (ESHRE) Arbeitsgemeinschaft der wissenschaftlichen medizinischen Fachgesellschaft (awmf) carried out. Results: addition cycle that occur physiologically as result cycles context immaturity hypothalamic–pituitary–gonadal axis, there are other abnormalities classified need recognized treated. Conclusions: Increasing awareness various specialist disciplines cooperation them have positive influence quality adolescent women with abnormalities.

Language: Английский

Citations

1
Endometriosis-Associated Ovarian Carcinoma DOI Creative Commons
Ioana Păvăleanu,

Teodora Ana Balan,

Tiberiu Nicolae Poparlan

et al.

IntechOpen eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 11, 2024

The link between endometriosis and ovarian carcinoma has been recognized early on, initially termed endometriosis-associated subsequently referred to as (EAOC). relationship cancer is well supported by epidemiological evidence, highlighting common risk factors. Two potential mechanisms have proposed: one involving the direct malignant transformation of endometriotic lesions, other suggesting a shared origin in precursor or factors, followed distinct molecular pathways. This chapter explores links, mechanisms, clinical implications carcinoma, its subtypes

Language: Английский

Citations

0