How to Preserve Fertility in Reproductive-Age Women with Cancer DOI Open Access

Sébastien Jaeck,

Chloé Depuydt,

Valérie Bernard

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(6), P. 1912 - 1912

Published: March 12, 2025

Chemotherapy and radiotherapy, among other gonadotoxic treatments, can significantly affect ovarian reserve function, potentially leading to premature insufficiency (POI) sterility. With the increasing survival rates young female cancer patients, fertility preservation (FP) has become an essential aspect of care. The decision pursue FP depends on various factors, including patient age, reserve, type treatment, its potential. Several strategies are available, oocyte, embryo, tissue cryopreservation. While oocyte embryo cryopreservation gold standard techniques, in vitro maturation (IVM) present viable alternatives for patients who cannot undergo stimulation or whom is contraindicated. Despite significant advances within practice, challenges remain ensuring timely counseling, equitable access services, optimizing long-term reproductive outcomes. Continued research needed refine existing explore innovative approaches, address ethical considerations decision-making. This review explores current options, their clinical applications, future directions improve outcomes women undergoing treatments.

Language: Английский

How to Preserve Fertility in Reproductive-Age Women with Cancer DOI Open Access

Sébastien Jaeck,

Chloé Depuydt,

Valérie Bernard

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(6), P. 1912 - 1912

Published: March 12, 2025

Chemotherapy and radiotherapy, among other gonadotoxic treatments, can significantly affect ovarian reserve function, potentially leading to premature insufficiency (POI) sterility. With the increasing survival rates young female cancer patients, fertility preservation (FP) has become an essential aspect of care. The decision pursue FP depends on various factors, including patient age, reserve, type treatment, its potential. Several strategies are available, oocyte, embryo, tissue cryopreservation. While oocyte embryo cryopreservation gold standard techniques, in vitro maturation (IVM) present viable alternatives for patients who cannot undergo stimulation or whom is contraindicated. Despite significant advances within practice, challenges remain ensuring timely counseling, equitable access services, optimizing long-term reproductive outcomes. Continued research needed refine existing explore innovative approaches, address ethical considerations decision-making. This review explores current options, their clinical applications, future directions improve outcomes women undergoing treatments.

Language: Английский

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