Natural Products and Health Care Functions of Inonotus obliquus DOI Creative Commons

Y.F. Wang,

Jingsheng Gu,

Jiaying Wu

et al.

Current Issues in Molecular Biology, Journal Year: 2025, Volume and Issue: 47(4), P. 269 - 269

Published: April 10, 2025

With the increasing attention of modern medicine to natural medicinal agents, Inonotus obliquus (chaga), a macrofungus with remarkable value, has gradually garnered widespread academic interest. This paper reviews primary bioactive components I. in recent years, including polysaccharides, phenolic compounds, and triterpenoids, which exhibit diverse pharmacological effects such as antioxidant, anti-inflammatory, immunomodulatory, antitumor activities. It further discusses how these enhance human health disease resistance through distinct biological mechanisms, activation antioxidant systems, regulation immune responses, modulation apoptosis pathways. Additionally, article explores biosynthetic pathways metabolites their relevance. Finally, we summarize potential resource envisage its future applications clinical drug development. review aims provide novel perspectives for cultivation, utilization, industrial-scale exploitation obliquus.

Language: Английский

Caffeine and Purine Derivatives: A Comprehensive Review on the Chemistry, Biosynthetic Pathways, Synthesis‐Related Reactions, Biomedical Prospectives and Clinical Applications DOI
Ameen A. Abu‐Hashem, Othman Hakami, Mohamed El‐Shazly

et al.

Chemistry & Biodiversity, Journal Year: 2024, Volume and Issue: 21(7)

Published: May 9, 2024

Caffeine and purine derivatives represent interesting chemical moieties, which show various biological activities. is an alkaloid that belongs to the family of methylxanthine alkaloids it present in food, beverages, drugs. Coffee, tea, some other beverages are a major source caffeine human diet. can be extracted from tea or coffee using hot water with dichloromethane chloroform leftover known as decaffeinated tea. its were synthesized via different procedures on small large scales. It competitively antagonizes adenosine receptors (ARs), G protein-coupled largely distributed body, including heart, vessels, brain, kidneys. Recently, many reports showed effect treatment diseases such Alzheimer's, asthma, parkinsonism, cancer. Also, used antioxidant, anti-inflammatory, analgesic, hypocholesterolemic agent. The review article discusses synthesis, reactivity, pharmacological properties derivatives. biosynthesis biotransformation leaves body summarized review.

Language: Английский

Citations

9
Natural Products and Health Care Functions of Inonotus obliquus DOI Creative Commons

Y.F. Wang,

Jingsheng Gu,

Jiaying Wu

et al.

Current Issues in Molecular Biology, Journal Year: 2025, Volume and Issue: 47(4), P. 269 - 269

Published: April 10, 2025

With the increasing attention of modern medicine to natural medicinal agents, Inonotus obliquus (chaga), a macrofungus with remarkable value, has gradually garnered widespread academic interest. This paper reviews primary bioactive components I. in recent years, including polysaccharides, phenolic compounds, and triterpenoids, which exhibit diverse pharmacological effects such as antioxidant, anti-inflammatory, immunomodulatory, antitumor activities. It further discusses how these enhance human health disease resistance through distinct biological mechanisms, activation antioxidant systems, regulation immune responses, modulation apoptosis pathways. Additionally, article explores biosynthetic pathways metabolites their relevance. Finally, we summarize potential resource envisage its future applications clinical drug development. review aims provide novel perspectives for cultivation, utilization, industrial-scale exploitation obliquus.

Language: Английский

Citations

0