Advances in understanding dietary fiber: Classification, structural characterization, modification, and gut microbiome interactions

Comprehensive Reviews in Food Science and Food Safety, Journal Year: 2025, Volume and Issue: 24(1)

Published: Jan. 1, 2025

Abstract Gut microbiota and their metabolites profoundly impact host physiology. Targeted modulation of gut has been a long‐term interest in the scientific community. Numerous studies have investigated feasibility utilizing dietary fibers (DFs) to modulate promote production health‐beneficial bacterial metabolites. However, complexity fiber structures, composition, dynamic interactions hindered precise prediction DF on microbiome. We address this issue with new perspective, focusing inherent chemical structural DFs interaction microbiota. The was thoroughly elaborated, encompassing fibers’ molecular polymorphism, mesoscopic porosity, particle size. Advanced characterization techniques investigate properties were discussed. Additionally, we examined between Finally, summarized processing modify structures for improving fermentability by structure fibers, such as crystallinity, degree branching, pore wettability, significantly impacts These differences also substantially affect fiber's capability composition Conventional approaches are not capable investigating complex influences microbiome; therefore, it is essence involve advanced material artificial intelligence unveil more comprehensive information topic.

Language: Английский

Postbiotics and their biotherapeutic potential for chronic disease and their feature perspective: a review

Frontiers in Microbiomes, Journal Year: 2025, Volume and Issue: 4

Published: March 3, 2025

Postbiotics, which are bioactive compounds derived from the metabolic processes of probiotics, gaining recognition as a promising alternative for managing chronic diseases without need live microorganisms, positioning them valuable strategy in biotherapeutics that offers both curative and preventive techniques modern medicine. This paper provides comprehensive review potential health benefits postbiotics, particularly concerning noncommunicable like diabetes, cancer, obesity cardiovascular conditions, present significant global challenges. We explore various mechanisms by postbiotics exert their beneficial effects, including immune modulation to enhance body’s response reduce inflammation, well improving gut barrier function maintain integrity prevent increased intestinal permeability. Additionally, antioxidant properties play critical role neutralizing oxidative stress, is linked progression diseases. Despite encouraging insights into benefits, we highlight urgent further research clarify specific roles different postbiotic components. A deeper understanding these essential developing targeted healthcare applications, advancing this knowledge, aim create innovative strategies could significantly outcomes at-risk populations. Ultimately, integrating interventions has improve care contribute overall well-being affected individuals communities.

Language: Английский

Functional foods in Mediterranean diet: exploring the functional features of vegetable case-studies obtained also by biotechnological approaches

Aging Clinical and Experimental Research, Journal Year: 2024, Volume and Issue: 36(1)

Published: Oct. 16, 2024

The Mediterranean Diet (MedDiet) is a widely recognized dietary pattern, with its effects largely attributed to "functional foods" which are able positively influence one or more target functions, improving health and maintaining state of well-being.In this review, three "case-study" typical the MedDiet, such as artichokes, capers table olives considered traditional functional vegetables rich in bioactive compounds, mainly polyphenols. review extensively discusses antioxidant these molecules, well their role aging prevention reduction, human health, influencing abundance composition intestinal microbiota. Additionally, focuses on fate polyphenols along digestive tract.Among biotechnological strategies, explores fermentation process modifying biochemical profile, recovery, bioaccessibility bioavailability compounds present some vegetable foods MedDiet. Finally, main challenges selection, addition, maintenance probiotic strains food products also summarized, view develop new carriers for diets".

Language: Английский