Journal of Heredity,
Journal Year:
2023,
Volume and Issue:
114(5), P. 504 - 512
Published: June 29, 2023
Abstract
Several
methods
exist
for
detecting
genetic
relatedness
or
identity
by
comparing
DNA
information.
These
generally
require
genotype
calls,
either
single-nucleotide
polymorphisms
short
tandem
repeats,
at
the
sites
used
comparison.
For
some
samples,
like
those
obtained
from
bone
fragments
single
rootless
hairs,
there
is
often
not
enough
present
to
generate
calls
that
are
accurate
and
complete
these
comparisons.
Here,
we
describe
IBDGem,
a
fast
robust
computational
procedure
genomic
regions
of
identity-by-descent
low-coverage
shotgun
sequence
data
against
known
query
individual.
At
less
than
1×
genome
coverage,
IBDGem
reliably
detects
segments
can
make
high-confidence
detections
with
as
little
0.01×
coverage.
Current Issues in Molecular Biology,
Journal Year:
2025,
Volume and Issue:
47(4), P. 252 - 252
Published: April 7, 2025
Bats
are
the
only
mammals
with
ability
to
fly
and
second
largest
order
after
rodents,
20
families
1213
species
(over
3000
subspecies)
widely
distributed
in
regions
around
world
except
for
Antarctica.
What
makes
bats
unique
their
biological
traits:
a
tolerance
zoonotic
infections
without
getting
clinical
symptoms,
long
lifespans,
low
incidence
of
tumors,
high
metabolism.
As
result,
they
receiving
increasing
attention
field
life
sciences,
particularly
medical
research.
The
rapid
advancements
sequencing
technology
have
made
it
feasible
comprehensively
analyze
diverse
characteristics
bats.
This
review
discusses
following:
(1)
assembly
annotation
overview
77
assemblies
from
54
across
11
transcriptome
42
7
families,
focused
on
comparative
analysis
genomic
architecture,
sensory
adaptations
(auditory,
visual,
olfactory),
immune
functions.
Key
findings
encompass
marked
interspecies
divergence
genome
size,
lineage-specific
expansions/contractions
immune-related
gene
(APOBEC,
IFN,
PYHIN),
linked
ecological
niches.
Notably,
echolocating
exhibited
convergent
evolution
auditory
genes
(SLC26A5
FOXP2),
while
fruit-eating
displayed
degeneration
vision-associated
(RHO),
reflecting
trade-offs
between
specialization
demands.
(2)
V
(variable),
D
(diversity),
J
(joining),
C
(constant)
TR
IG
loci
12
five
focus
differences
CDR3
repertoires
different
other
mammals,
provides
us
deeper
understanding
development
function
system
organisms.
Integrated
genomic,
transcriptomic,
repertoire
analyses
reveal
that
employ
distinct
antiviral
strategies,
primarily
mediated
by
enhanced
suppressed
inflammatory
responses.
foundational
information,
collaboration
directions,
new
perspectives
various
laboratories
conducting
basic
applied
research
vast
array
bat
biology.
Journal of Heredity,
Journal Year:
2022,
Volume and Issue:
113(6), P. 597 - 603
Published: Sept. 1, 2022
Abstract
Incorporating
measures
of
taxonomic
diversity
into
research
and
management
plans
has
long
been
a
tenet
conservation
science.
Increasingly,
active
programs
are
turning
toward
multispecies
landscape
regional
actions,
away
from
single
species
approaches.
This
is
both
reflection
changing
trends
in
science
advances
foundational
technologies,
including
genomics
geospatial
Multispecies
approaches
may
provide
more
fundamental
insights
evolutionary
processes
equip
managers
with
holistic
understanding
the
landscapes
under
their
jurisdiction.
Central
to
this
approach
data
generation
analyses
which
embrace
reflect
broad
range
diversity.
Here,
we
examine
family-level
phylogenetic
breadth
California
Conservation
Genomics
Project
(CCGP)
based
on
(PD),
distinctness,
family
richness.
We
place
context
present
compare
it
35-plus
years
genetic
compiled
CaliPopGen
Database.
found
that
PD
CCGP
reflected
very
well,
slightly
overrepresenting
chordates
underrepresenting
arthropods,
42%
represented
new
contributions
for
state.
In
one
focused
effort,
was
able
achieve
roughly
half
studied
over
last
several
decades.
To
maximize
PD,
future
work
should
focus
conclusion
likely
reflects
overall
lack
attention
hyperdiverse
clade.
Globally,
national,
subnational,
and
supranational
entities
are
creating
Biodiversity
Strategy
Action
Plans,
to
develop
concrete
commitments
actions
curb
biodiversity
loss,
meet
international
obligations
achieve
a
society
in
harmony
with
nature.
In
light
of
policy
makers'
increasing
recognition
genetic
diversity
helping
species
ecosystems
adapt
be
resilient
during
environmental
change,
this
article
provides
an
overview
how
BSAPs
can
better
incorporate
conservation
within
species.
We
focus
on
three
areas:
setting
targets;
committing
actions,
policies
programmes;
monitoring
reporting.
Examples
policies,
knowledge,
projects,
capacity
building,
other
endeavors
drawn
from
20
recent
around
the
world.
aim
enable
inspire
specific
ambitious
BSAPs,
so
guidance
suggestions
summarized
portrayed
“the
cycle.”
With
this,
scientists
makers
translate
high
level
like
CBD
into
nationally-relevant
targets,
reporting
mechanisms.
Journal of Heredity,
Journal Year:
2023,
Volume and Issue:
114(5), P. 504 - 512
Published: June 29, 2023
Abstract
Several
methods
exist
for
detecting
genetic
relatedness
or
identity
by
comparing
DNA
information.
These
generally
require
genotype
calls,
either
single-nucleotide
polymorphisms
short
tandem
repeats,
at
the
sites
used
comparison.
For
some
samples,
like
those
obtained
from
bone
fragments
single
rootless
hairs,
there
is
often
not
enough
present
to
generate
calls
that
are
accurate
and
complete
these
comparisons.
Here,
we
describe
IBDGem,
a
fast
robust
computational
procedure
genomic
regions
of
identity-by-descent
low-coverage
shotgun
sequence
data
against
known
query
individual.
At
less
than
1×
genome
coverage,
IBDGem
reliably
detects
segments
can
make
high-confidence
detections
with
as
little
0.01×
coverage.
