Aquaculture, Journal Year: 2024, Volume and Issue: unknown, P. 742084 - 742084
Published: Dec. 1, 2024
Language: Английский
Aquaculture, Journal Year: 2024, Volume and Issue: unknown, P. 742084 - 742084
Published: Dec. 1, 2024
Language: Английский
bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 28, 2024
Eye loss is a hallmark trait of animals inhabiting perpetual darkness, such as caves. The Mexican tetra (
Language: Английский
Citations
1bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 15, 2024
Abstract Uncovering mechanisms by which sensory systems evolve is critical for understanding how organisms adapt to a novel environment. Astyanax mexicanus species of fish with populations surface that inhabit rivers and streams cavefish have adapted life within caves. Cavefish evolved system changes relative their counterparts, providing an opportunity investigate underlying evolution. Here, we report the role gene retinal homeobox 3 ( rx3 ) in eye We generated putative loss-of-function mutations using CRISPR-Cas9 determine this development species. These mutant fail develop eyes, demonstrating required development. Further, exhibit altered behaviors wild-type fish, suggesting loss eyes impacts sensory-dependent behaviors. Finally, cave-surface hybrid inherit allele from siblings allele, cis-regulatory variation at locus contributes size evolution cavefish. Together, these findings demonstrate that, as other species, A. . Moreover, they suggest plays reduction cavefish, shedding light on genetic response extreme environmental changes.
Language: Английский
Citations
0Aquaculture, Journal Year: 2024, Volume and Issue: unknown, P. 742084 - 742084
Published: Dec. 1, 2024
Language: Английский
Citations
0