Multiple mechanisms associated with deltamethrin and imidacloprid resistance in field-collected common bed bug, Cimex lectularius L.
Pesticide Biochemistry and Physiology,
Journal Year:
2025,
Volume and Issue:
210, P. 106357 - 106357
Published: March 2, 2025
Pyrethroids
and
neonicotinoids
are
commonly
used
to
manage
the
common
bed
bug
(Cimex
lectularius
L.)
infestations.
However,
effectiveness
of
these
insecticides
is
often
challenged
due
insecticide
resistance.
We
investigated
mechanisms
deltamethrin
imidacloprid
resistance
in
eight
C.
strains
collected
from
New
Jersey,
U.S.
Piperonyl
butoxide
(PBO),
S,S,S-tributyl
phosphorotrithioate
(DEF),
diethyl
maleate
(DEM)
were
topically
applied
on
bugs
before
or
treatments
(deltamethrin:
115
ng
per
adult;
imidacloprid:
67
adult).
The
results
showed
that
PBO
DEF
had
a
greater
synergistic
effect
with
than
DEM
based
significantly
increased
72
h
mortality
Aberdeen,
Bayonne
2015,
Cotton,
Irvington,
Irvington
624-5G
strains.
With
alone,
seven
out
experienced
100
%
except
for
Linden
2019
strain.
strain
mean
mortalities
93,
97,
47
after
receiving
PBO,
DEF,
DEM,
respectively.
activities
glutathione
S-transferase
general
esterase
all
enhanced
compared
susceptible
Molecular
detection
voltage-gated
sodium
channel
(VGSC)
mutations
revealed
homozygous
V419L
L925I
at
20-100
30-100
frequency,
presence
both
was
found
individuals
each
resistant
indicate
combination
metabolic
target
site
insensitivity
confers
lectularius.
Language: Английский
Global Perspective of Insecticide Resistance in Bed Bugs and Management Options
Entomological Research,
Journal Year:
2025,
Volume and Issue:
55(4)
Published: March 28, 2025
ABSTRACT
The
global
resurgence
of
bed
bugs
(
Cimex
lectularius
L.
and
hemipterus
[F.])
over
the
past
25
years
has
presented
significant
challenges
to
pest
management
industry,
with
insecticide
resistance
as
a
leading
cause
control
failures.
This
review
provides
synthesis
bug
research
from
2018
present,
highlighting
profiles,
mechanisms,
strategies.
Resistance
pyrethroids,
neonicotinoids,
organophosphates,
carbamates,
other
insecticides
is
widespread,
documented
cases
metabolic
(cytochrome
P450s,
esterases,
glutathione
S‐transferase
ABC
transporters),
target
site
insensitivity
(point
mutations
in
voltage‐gated
sodium
channel
genes
[
kdr
],
paralogous
acetylcholinesterase
gene
p‐Ace
),
GABA
receptor
rdl
]),
penetration
(cuticular
thickening),
symbiont‐mediated
resistance.
paper
also
reviews
effective
options
against
insecticide‐resistant
bugs,
including
mixtures
synergists,
entomopathogenic
fungi
Beauveria
bassiana
physical
methods
such
heat
treatment,
desiccant
dust,
fumigation.
Additionally,
novel
approaches,
RNA
interference
baits,
provide
new
directions
but
require
further
research.
Lastly,
socio‐economic
disparities
affect
management,
especially
lower‐income
communities.
Language: Английский