How Pathophysiology Explains Risk and Protective Factors

Published: Jan. 1, 2025

Language: Английский

Platelet Pathophysiology: Unexpected New Research Directions

Seminars in Thrombosis and Hemostasis, Journal Year: 2024, Volume and Issue: 50(08), P. 1187 - 1190

Published: June 18, 2024

We are very honored that our 2016 review of platelet physiology[1] is one the top three most downloaded papers in Seminars and Thrombosis Haemostasis from 2014 to 2023. But why study physiology? Because these remarkable little cells play key roles many important pathophysiological processes, including thrombosis, hemorrhage, inflammation, antimicrobial host defense, wound healing, angiogenesis, tumor growth metastasis.[2] In addition primary disorders number function, platelets have a critical role other common diseases, coronary artery disease, stroke, peripheral vascular diabetes mellitus.[2] There remain incompletely understood aspects physiology its relationship few examples which innate adaptive immunity,[3] [4] genetic basis thrombocytopenia,[5] activation coronavirus disease 2019,[6] liver disease,[7] novel targets for antiplatelet therapy.[8] [9] [10] science general, particular, can sometimes lead researchers an unexpected new direction, as will be discussed this commentary focused on between function sudden infant death syndrome (SIDS).

Language: Английский

Substance P and sudden infant death syndrome (SIDS)

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 611 - 623

Published: Nov. 8, 2024

Language: Английский