Inversions encounter relaxed genetic constraints and balance birth and death of TPS genes in Curcuma DOI Creative Commons
Xuezhu Liao, Dejin Xie, Tingting Bao

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: Oct. 29, 2024

Evolutionary dynamics of inversion and its impact on biochemical traits are a puzzling question. Here, we show abundance inversions in three Curcuma species (turmeric, hidden ginger Siam tulip). Genes within display higher long terminal repeat content lower expression level compared with genomic background, suggesting experience relaxed genetic constraints. It is corroborated by depletion selected SNPs enrichment deleterious mutations detected among 56 tulip cultivars. Functional verification tandem duplicated terpene synthase (TPS) genes reveals that become pseudogenes, while outside retain catalytic function. Our findings suggest act as counteracting force against duplication balancing birth death TPS modulating terpenoid contents Curcuma. This study provides an empirical example likely not adaptive but affect traits.

Language: Английский

Introgression dynamics of sex-linked chromosomal inversions shape the Malawi cichlid adaptive radiation DOI Creative Commons
Moritz Blumer, Valentina Burskaia, I. V. Artyushin

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: July 29, 2024

Abstract Chromosomal inversions contribute to adaptive speciation by linking co-adapted alleles. Querying 1,375 genomes of the species-rich Malawi cichlid fish radiation, we discovered five large segregating in benthic subradiation that each suppress recombination over more than half a chromosome. Two were transferred from deepwater pelagic Diplotaxodon via admixture, while others established early deep clade. Introgression haplotypes lineages inside and outside radiation coincided with bursts species diversification. Inversions show evidence for transient sex linkage striking excess protein changing substitutions points towards selection on neuro-sensory, physiological reproductive genes. We conclude repeated interplay between depth adaptation sex-specific has been central evolution this iconic system.

Language: Английский

Citations

8
Inversions encounter relaxed genetic constraints and balance birth and death of TPS genes in Curcuma DOI Creative Commons
Xuezhu Liao, Dejin Xie, Tingting Bao

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: Oct. 29, 2024

Evolutionary dynamics of inversion and its impact on biochemical traits are a puzzling question. Here, we show abundance inversions in three Curcuma species (turmeric, hidden ginger Siam tulip). Genes within display higher long terminal repeat content lower expression level compared with genomic background, suggesting experience relaxed genetic constraints. It is corroborated by depletion selected SNPs enrichment deleterious mutations detected among 56 tulip cultivars. Functional verification tandem duplicated terpene synthase (TPS) genes reveals that become pseudogenes, while outside retain catalytic function. Our findings suggest act as counteracting force against duplication balancing birth death TPS modulating terpenoid contents Curcuma. This study provides an empirical example likely not adaptive but affect traits.

Language: Английский

Citations

3