Chromosome-level genome assembly and annotation of the gynogenetic large-scale loach (Paramisgurnus dabryanus) DOI Creative Commons
Lei Zhang, Wanting Zhang,

Yingyin Cheng

et al.

Scientific Data, Journal Year: 2025, Volume and Issue: 12(1)

Published: Jan. 26, 2025

Abstracts The large-scale loach ( Paramisgurnus dabryanus ; Cypriniformes: Cobitidae) is primarily distributed in East Asia. It an important economic fish species characterized by fast growth, temperature-dependent sex determination and the ability to breathe air. Currently, molecular mechanism studies related some aspects such as determination, toxicology, feed nutrition, growth genetic evolution have been conducted. However, lack of a high-quality reference genome has hindered further research. In this study, we performed PacBio HiFi Hi-C sequencing on female (ZW) specimen assembled first chromosome-level loach. comprises 24 chromosomes, with total length 1.04 Gb, scaffold N50 41.7 Mb, BUSCO completeness 95.8%, including 28,311 protein-coding genes. These findings not only provide new insights into structure but also establish crucial point for omics serve essential genomic resource breeding programs species.

Language: Английский

Chromosome-level genome assembly of a destructive leaf-mining moth Eriocrania semipurpurella alpina DOI Creative Commons

Gui-fang Wang,

Jianfeng He, Cheng Sun

et al.

Scientific Data, Journal Year: 2025, Volume and Issue: 12(1)

Published: Jan. 2, 2025

Language: Английский

Citations

0
Inulin improved endometrial ciliary damage caused by DEHP and nanoplastics co-exposure DOI Creative Commons
Peigen Chen, Lina Chen, Xing Yang

et al.

Journal of Hazardous Materials Advances, Journal Year: 2025, Volume and Issue: unknown, P. 100590 - 100590

Published: Jan. 1, 2025

Language: Английский

Citations

0
Comparing acute versus AIDS ART initiation on HIV-1 integration sites and clonal expansion DOI Creative Commons
Jun Wang, Nan Xiao,

Zhengnong Zhu

et al.

Signal Transduction and Targeted Therapy, Journal Year: 2025, Volume and Issue: 10(1)

Published: Jan. 9, 2025

Abstract Early antiretroviral therapy (ART) initiation is known to limit the establishment of HIV reservoir, with studies suggesting benefits such as a reduced number infected cells and smaller latent reservoir. However, long-term impact early ART on dynamics cell pool remains unclear, clinical evidence directly comparing proviral integration site counts between late limited. In this study, we used Linear Target Amplification-PCR (LTA-PCR) Next Generation Sequencing compare unique (UIS) clonal individuals who initiated during acute infection stage (Acute-ART group) those in AIDS (AIDS-ART group). Our analysis revealed distinct distribution patterns, greater UIS heterogeneity Acute-ART group more homogeneity AIDS-ART group. Monoclonal accumulation, predominantly in-gene regions, was influenced by timing duration, treatment delaying process. Host genes integrated provirus monoclonal types were enriched cycle lymphocyte activation pathways. Tumor suppressor (TSGs) frequently group, potential risk factors. Overall, introduced sequencing method assess size human peripheral blood identified widespread presence after treatment. The intervention helps slow progress expansion cells, reducing formation stable persistent reservoirs, ultimately posing fewer barriers achieving functional cure.

Language: Английский

Citations

0
Responses of microbial communities in coastal sediments exposed to triclocarban and triclosan DOI
Jingwei Wang, Peng Zhao, Jiaxin Wang

et al.

Marine Pollution Bulletin, Journal Year: 2025, Volume and Issue: 212, P. 117530 - 117530

Published: Jan. 10, 2025

Language: Английский

Citations

0
Chromosome-level genome assembly and annotation of the gynogenetic large-scale loach (Paramisgurnus dabryanus) DOI Creative Commons
Lei Zhang, Wanting Zhang,

Yingyin Cheng

et al.

Scientific Data, Journal Year: 2025, Volume and Issue: 12(1)

Published: Jan. 26, 2025

Abstracts The large-scale loach ( Paramisgurnus dabryanus ; Cypriniformes: Cobitidae) is primarily distributed in East Asia. It an important economic fish species characterized by fast growth, temperature-dependent sex determination and the ability to breathe air. Currently, molecular mechanism studies related some aspects such as determination, toxicology, feed nutrition, growth genetic evolution have been conducted. However, lack of a high-quality reference genome has hindered further research. In this study, we performed PacBio HiFi Hi-C sequencing on female (ZW) specimen assembled first chromosome-level loach. comprises 24 chromosomes, with total length 1.04 Gb, scaffold N50 41.7 Mb, BUSCO completeness 95.8%, including 28,311 protein-coding genes. These findings not only provide new insights into structure but also establish crucial point for omics serve essential genomic resource breeding programs species.

Language: Английский

Citations

0