The 2025 Nucleic Acids Research database issue and the online molecular biology database collection DOI Creative Commons
Daniel J. Rigden, Xosé M. Fernández

Nucleic Acids Research, Journal Year: 2024, Volume and Issue: 53(D1), P. D1 - D9

Published: Dec. 10, 2024

The 2025 Nucleic Acids Research database issue contains 185 papers spanning biology and related areas. Seventy three new databases are covered, while resources previously described in the account for 101 update articles. Databases most recently published elsewhere a further 11 papers. acid include EXPRESSO multi-omics of 3D genome structure (this issue's chosen Breakthrough Resource Article) NAIRDB Fourier transform infrared data. New protein predictions human isoforms at ASpdb viral proteins BFVD. UniProt, Pfam InterPro have all provided updates: metabolism signalling covered by descriptions STRING, KEGG CAZy, updated microbe-oriented Enterobase, VFDB PHI-base. Biomedical research is supported, among others, ClinVar, PubChem DrugMAP. Genomics-related Ensembl, UCSC Genome Browser dbSNP. plant cover Solanaceae (SolR) Asteraceae (AMIR) families an from NCBI Taxonomy also features. Database Issue freely available on website (https://academic.oup.com/nar). At NAR online Molecular Biology Collection (http://www.oxfordjournals.org/nar/database/c/), 932 entries been reviewed last year, 74 added 226 discontinued URLs eliminated bringing current total to 2236 databases.

Language: Английский

Engineering tomato disease resistance by manipulating susceptibility genes DOI Creative Commons
Duoduo Wang, Palash Mandal, Md. Mostafizur Rahman

et al.

Frontiers in Genome Editing, Journal Year: 2025, Volume and Issue: 7

Published: Feb. 10, 2025

Various pathogens severely threaten tomato yield and quality. Advances in understanding plant-pathogen interactions have revealed the intricate roles of resistance (R) susceptibility (S) genes determining plant immunity. While R provide targeted pathogen resistance, they are often vulnerable to evolution. Conversely, S offer a promising avenue for developing broad-spectrum durable through gene editing. Recent breakthroughs CRISPR/Cas-based technologies revolutionized manipulation genomes, enabling precise modification enhance disease without compromising growth or However, utilization full potential this technique is challenging due complex current technological limitations. This review highlights key advances using editing tools dissect engineer improved We discuss how influence entry, immune suppression, nutrient acquisition, their has conferred bacterial, fungal, viral pathogens. Furthermore, we address challenges associated with growth-defense trade-offs propose strategies, such as hormonal pathway modulation regulatory edits, overcome these underscores CRISPR-based approaches transform breeding, paving way sustainable production disease-resistant cultivars amidst escalating global food security challenges.

Language: Английский

Citations

0
Alkaloid evolution in the Solanaceae DOI

Pablo A. Pérez-Mesa,

Federico Roda

Current Opinion in Plant Biology, Journal Year: 2025, Volume and Issue: 85, P. 102727 - 102727

Published: April 26, 2025

Language: Английский

Citations

0
plantGIR: a genomic database of plants DOI Creative Commons
Zhuo Liu, Chenhao Zhang, Jinghua He

et al.

Horticulture Research, Journal Year: 2024, Volume and Issue: 11(12)

Published: Dec. 1, 2024

Language: Английский

Citations

2
Genome-Wide Analysis of the NBS-LRR Gene Family and SSR Molecular Markers Development in Solanaceae DOI Creative Commons

Xiaoming Song,

Chunjin Li, Zhuo Liu

et al.

Horticulturae, Journal Year: 2024, Volume and Issue: 10(12), P. 1293 - 1293

Published: Dec. 4, 2024

The Solanaceae family occupies a significant position, and the study of resistance genes within this is extremely valuable. Therefore, our goal to examine disease based on high-quality representative genomes crops, develop corresponding Simple Sequence Repeat (SSR) molecular markers. Among nine species, we identified 819 NBS-LRR genes, which were further divided into 583 CC-NBS-LRR (CNL), 54 RPW8-NBS-LRR (RNL), 182 TIR-NBS-LRR (TNL) genes. Whole genome duplication (WGD) has played very important role in expansion crops. Gene structure analysis showed striking similarity conserved motifs suggests common ancestral origin, followed by evolutionary differentiation amplification. clustering events like rearrangement contribute their scattered chromosomal distribution. Our findings reveal that majority across all examined species predominantly localize termini. indicates impact most recent whole triplication (WGT) Moreover, constructed Protein–Protein Interaction (PPI) networks for identifying 3820 potential PPI pairs. Notably, 97 displayed clear interactive relationships, highlighting processes. A total 22,226 SSRs detected from species. these SSRs, screened 43 NBS-LRR-associated SSRs. lays foundation exploration SSR development genetic mapping related

Language: Английский

Citations

1
The 2025 Nucleic Acids Research database issue and the online molecular biology database collection DOI Creative Commons
Daniel J. Rigden, Xosé M. Fernández

Nucleic Acids Research, Journal Year: 2024, Volume and Issue: 53(D1), P. D1 - D9

Published: Dec. 10, 2024

The 2025 Nucleic Acids Research database issue contains 185 papers spanning biology and related areas. Seventy three new databases are covered, while resources previously described in the account for 101 update articles. Databases most recently published elsewhere a further 11 papers. acid include EXPRESSO multi-omics of 3D genome structure (this issue's chosen Breakthrough Resource Article) NAIRDB Fourier transform infrared data. New protein predictions human isoforms at ASpdb viral proteins BFVD. UniProt, Pfam InterPro have all provided updates: metabolism signalling covered by descriptions STRING, KEGG CAZy, updated microbe-oriented Enterobase, VFDB PHI-base. Biomedical research is supported, among others, ClinVar, PubChem DrugMAP. Genomics-related Ensembl, UCSC Genome Browser dbSNP. plant cover Solanaceae (SolR) Asteraceae (AMIR) families an from NCBI Taxonomy also features. Database Issue freely available on website (https://academic.oup.com/nar). At NAR online Molecular Biology Collection (http://www.oxfordjournals.org/nar/database/c/), 932 entries been reviewed last year, 74 added 226 discontinued URLs eliminated bringing current total to 2236 databases.

Language: Английский

Citations

1