Psychedelics and disorders of consciousness: the current landscape and the path forward
Neuroscience of Consciousness,
Journal Year:
2024,
Volume and Issue:
2024(1)
Published: Jan. 1, 2024
Modern
medicine
has
been
shaken
by
the
surge
of
psychedelic
science
that
proposes
a
new
approach
to
mitigate
mental
disorders,
such
as
depression
and
post-traumatic
stress
disorder.
Clinical
trials
investigate
whether
substances
can
treat
psychiatric
conditions
are
now
underway,
yet
less
discussion
gravitates
around
their
use
in
neurological
disorders
due
brain
injury.
One
suggested
implementation
brain-complexity
enhancing
psychedelics
is
people
with
post-comatose
consciousness
(DoC).
In
this
article,
we
discuss
rationale
endeavour,
examining
possible
outcomes
experiments
postulating
existence
an
optimal
level
complexity.
We
consider
counterintuitive
effects
both
DoC
on
functional
connectivity
default
mode
network
its
impact
selfhood.
also
elaborate
role
computational
modelling
providing
complementary
information
experimental
studies,
contributing
our
understanding
treatment
mechanisms
path
towards
personalized
medicine.
Finally,
update
discourse
surrounding
ethical
considerations,
encompassing
clinical
scientific
values.
Language: Английский
Feedforward connectivity patterns from visual areas to the front of the brain contain information about sensory stimuli regardless of awareness or report
Cortex,
Journal Year:
2023,
Volume and Issue:
172, P. 284 - 300
Published: Dec. 9, 2023
Current
theories
of
consciousness
can
be
categorized
to
some
extent
by
their
predictions
about
the
putative
role
prefrontal
cortex
(PFC)
in
conscious
perception.
One
family
proposes
that
PFC
is
necessary
for
The
other
postulates
not
and
areas
(e.g.,
posterior
cortical
areas)
are
more
important
No-report
paradigms
could
potentially
arbitrate
debate
as
they
disentangle
task
reporting
from
While
previous
no-report
tend
point
a
reduction
activity,
have
examined
critical
"monitoring"
or
"reading
out"
patterns
activity
sensory
generate
To
address
this,
we
reanalysed
electroencephalography
(EEG)
data
inattentional
blindness
paradigm
(Shafto
&
Pitts,
2015).
We
feedforward
input
cortices.
employed
nonparametric
spectral
Granger
causality
quantified
amount
information
reflected
contents
using
multivariate
classifiers.
Unexpectedly,
regardless
whether
stimulus
was
consciously
seen
not,
found
relating
current
present
pattern
inputs
visual
PFC.
In
light
these
findings,
suggest
various
need
revised
accommodate
fact
decodable
regions
PFC,
awareness
(or
report).
Language: Английский
What does it mean for consciousness to be multidimensional? A narrative review
Julie Páleník
No information about this author
Frontiers in Psychology,
Journal Year:
2024,
Volume and Issue:
15
Published: June 20, 2024
A
recent
development
in
the
psychological
and
neuroscientific
study
of
consciousness
has
been
tendency
to
conceptualize
as
a
multidimensional
phenomenon.
This
narrative
review
elucidates
notion
dimensionality
outlines
key
concepts
disagreements
on
this
topic
through
viewpoints
several
theoretical
proposals.
The
reviewed
literature
is
critically
evaluated,
main
issues
be
resolved
by
future
empirical
work
are
identified:
problems
dimension
selection
aggregation,
well
some
ethical
considerations.
seemingly
first
comprehensively
overview
specific
aspect
science.
Language: Английский
Feedforward connectivity patterns from visual areas to the front of the brain contain information about sensory stimuli regardless of awareness or report
Published: June 2, 2023
Current
theories
of
consciousness
can
be
categorized
to
some
extent
by
their
predictions
about
the
putative
role
prefrontal
cortex
(PFC)
in
conscious
perception.
One
family
proposes
that
PFC
is
necessary
for
The
other
postulates
not
and
areas
(e.g.,
posterior
cortical
areas)
are
more
important
No-report
paradigms
could
potentially
arbitrate
debate
as
they
disentangle
task
reporting
from
While
previous
no-report
tend
point
a
reduction
activity,
have
examined
critical
“monitoring”
or
“reading
out”
patterns
activity
sensory
generate
To
address
this,
we
reanalysed
EEG
data
inattentional
blindness
paradigm
(Shafto
&
Pitts,
2015).
We
feedforward
input
cortices.
employed
nonparametric
spectral
Granger
causality
quantified
amount
information
reflected
contents
using
multivariate
classifiers.
Unexpectedly,
regardless
whether
stimulus
was
consciously
seen
not,
found
relating
current
present
pattern
inputs
visual
PFC.
In
light
these
findings,
suggest
various
need
revised
accommodate
fact
decodable
regions
PFC,
awareness
(or
report).
Language: Английский
When do parts form wholes? Integrated information as the restriction on mereological composition
Neuroscience of Consciousness,
Journal Year:
2023,
Volume and Issue:
2023(1)
Published: Jan. 1, 2023
Under
what
conditions
are
material
objects,
such
as
particles,
parts
of
a
whole
object?
This
is
the
composition
question
and
longstanding
open
in
philosophy.
Existing
attempts
to
specify
non-trivial
restriction
on
tend
be
vague
face
serious
counterexamples.
Consequently,
two
extreme
answers
have
become
mainstream:
(the
forming
by
its
parts)
happens
under
no
or
all
conditions.
In
this
paper,
we
provide
self-contained
introduction
integrated
information
theory
(IIT)
consciousness.
We
show
that
IIT
specifies
composition:
when
maximized.
compare
existing
proposals
argue
has
significant
advantages,
especially
response
problems
vagueness
An
appendix
provides
an
calculating
wholes
with
simple
system.
Language: Английский
Meta-Representations as Representations of Processes
Ryota Kanai,
No information about this author
Ryota Takatsuki,
No information about this author
Ippei Fujisawa
No information about this author
et al.
Published: March 4, 2024
In
this
study,
we
explore
how
the
notion
of
meta-representations
in
Higher-Order
Theories
(HOT)
consciousness
can
be
implemented
computational
models.
HOT
suggests
that
emerges
from
meta-representations,
which
are
representations
first-order
sensory
representations.
However,
translating
abstract
concept
into
a
concrete
model,
such
as
those
used
artificial
intelligence,
presents
theoretical
challenge.
For
example,
simplistic
interpretation
meta-representation
representation
makes
rather
trivial
and
ubiquitous.
Here,
propose
refined
meta-representations.
Contrary
to
view
mere
transformations
representational
states
or
confidence
estimates,
argue
processes
generate
This
process-oriented
whereby
capture
qualitative
aspect
information
is
transformed
To
concretely
illustrate
operationalize
thus
formulated
meta-representation,
constructed
"meta-networks"
designed
explicitly
model
within
deep
learning
architectures.
Specifically,
meta-networks
by
implementing
autoencoders
neural
networks.
architecture,
latent
spaces
embedding
networks
correspond
By
applying
embed
trained
encode
visual
auditory
datasets,
show
successfully
aspects
separating
space.
We
would
useful
for
quantitatively
compare
contrast
differences
processes.
While
whether
meta-representational
systems
exist
human
brain
remains
an
open
question,
formulation
offers
new
empirically
testable
hypothesis
there
regions
represent
transforming
one
region
another
region.
Furthermore,
form
might
underlie
our
ability
describe
experience
qualia.
Language: Английский