Cancers, Journal Year: 2025, Volume and Issue: 17(2), P. 247 - 247
Published: Jan. 14, 2025
Background: Colorectal cancer primarily affects older adults and poses treatment challenges due to age-related comorbidities frailty, which hinder surgical chemotherapy options for many elderly patients. This study aims analyze disease patterns in colorectal patients, aged over 80 years old, inform personalized therapies that accommodate their unique clinical needs improve outcomes. Patients Methods: The medical records of all patients old above, those 65 75 who were diagnosed with at a center Canada seven year period, retrospectively reviewed. Results: No significant differences the initial presentation, location, grade or stage diagnosis observed between age groups. above less likely receive neoadjuvant adjuvant treatments II (19.2% versus. 58.6%, p = 0.002; 7.9% 40.0%, 0.002). There also intensity received frequency dose reductions (76.0% vs. 10.0%, 0.0001), radiation therapy (34.6% 65.5%, 0.02) management (83.7% 95.3%, 0.006). Despite these treatments, recurrence rates not statistically two However, overall survival was reduced group. Conclusions: Treatment plans should be tailored patient’s comorbidity status life expectancy, weighing impact on short- long-term
Language: Английский