Exploring ABI5 regulation: Post‐translational control and cofactor interactions in ABA signaling

The Plant Journal, Journal Year: 2025, Volume and Issue: 121(3)

Published: Feb. 1, 2025

SUMMARY Abscisic acid insensitive 5 (ABI5) is a pivotal transcription factor in abscisic (ABA) signaling, playing an essential role plant growth and responses to abiotic stress. This key regulator subject multifaceted regulation, especially on post‐translational mechanisms. Recent research has shed light the regulation of ABI5, encompassing both modifications (PTMs) modulation its transcriptional activity. In this review, we provide comprehensive overview current knowledge surrounding along with influence various cofactors activity protein stability. The potential biological roles PTMs ABI5 context ABA signaling stress are also explored. As one most extensively studied proteins environmental responses, sophisticated precise understanding regulatory mechanisms that govern not only beneficial for application genetic engineering but helpful our exploration fundamental principles regulation.

Language: Английский

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Metabolic pathway for evaluation of polyunsaturated fatty acids content variation and regulation of its biosynthesis in Paeonia ostii through abscisic acid and ABSCISIC ACID-INSENSITIVE 5 (PoABI5)

Industrial Crops and Products, Journal Year: 2025, Volume and Issue: 227, P. 120758 - 120758

Published: March 6, 2025

Language: Английский

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The transcriptional regulation of Arabidopsis ECT8 by ABA-Responsive Element binding transcription factors in response to ABA and abiotic stresses

Physiology and Molecular Biology of Plants, Journal Year: 2025, Volume and Issue: 31(3), P. 343 - 355

Published: March 1, 2025

Language: Английский

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OsbHLH062 negatively regulates Fe homeostasis by enhancing OsHRZ1 targeting OsPRIs for degradation

New Phytologist, Journal Year: 2025, Volume and Issue: unknown

Published: May 10, 2025

Summary Iron (Fe) is crucial for plant growth and development, many transcription factors are involved in the maintenance of Fe homeostasis. In rice signaling, basic helix–loop–helix (bHLH) IVc proteins (OsPRI1/OsbHLH060, OsPRI2/OsbHLH058, OsPRI3/OsbHLH059, OsPRI4/OsbHLH057) act as positive regulators, while Oryza sativa IRON‐RELATED BHLH TRANSCRIPTION FACTOR 3 (OsIRO3/OsbHLH063) functions a negative regulator. Additionally, HEMERYTHRIN MOTIF‐CONTAINING REALLY INTERESTING NEW GENE AND ZINC‐FINGER PROTEIN1 (OsHRZ1) plays role targeting OsPRIs degradation. Here, we investigated OsbHLH062 response to deficiency. We revealed that directly binds promoter region bHLH 2 ( OsIRO2) , thereby repressing its activity through recruitment corepressors TOPLESS/TOPLESSRELATED (OsTPL/OsTPRs). When both OsIRO3 mutated simultaneously, it results stunted root growth, reduced height, elevated concentration, upregulation deficiency inducible genes. found be localized cytoplasm nucleus. The interaction with promotes accumulation Our findings also reveal physically interact OsHRZ1, which turn enhances between OsHRZ1 OsPRI3, leading degradation OsPRI3 by OsHRZ1. These shed light on new function potential cofactors contribute reduction OsPRI and, consequently, repression signaling pathways.

Language: Английский

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Focus on proteolysis

The Plant Cell, Journal Year: 2024, Volume and Issue: 36(9), P. 2929 - 2930

Published: June 25, 2024

Proteolysis is an essential cellular function mediating the processing and turnover of proteins to remove damaged or inactive proteins, alter protein (binding enzymatic activities), ensure appropriate stoichiometries in cell.The post-translational control stability also a central feature signaling eukaryotes, i.e. regulating important regulatory crucial for almost all aspects plant biology, including vegetative growth, development, reproduction, stress responses.Proteolysis plays role hormone pathways, defense against pests pathogens, abiotic responses, basic cell functions like cycle, metabolism, organellar biogenesis maintenance, senescence.Compared with animals, genomes encode highly expanded number components related proteolytic pathways ubiquitin-proteasome system, autophagy, programmed death, endosomal trafficking, organelle-associated degradation.Recent advances molecular genetics microscopy high-resolution imaging, vivo labeling, proteomics, mass spectrometry, structural biology have led new insights understanding many areas proteolysis, autophagy chloroplasts other organelles, degradation membrane discovery N-degron involved development environmental responses (immunity stress).Knowledge systems agriculture breeding, given impact on growth yield, as well resistance diseases.This focus issue proteolysis includes two letters editor, one commentary, nine review articles, eight original research articles.The address question whether polyubiquitin pathway operates inside intact chloroplasts.The posed by van Wijk Adam (2024), Reply from Jarvis et al. (2024).Researchers both sides debate make valid points be considered.We eagerly await more definitive data arrive at complete commentary Eckardt

Language: Английский

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Genome-wide analyses of Ariadne family genes reveal their involvement in abiotic stress responses in apple

Gene, Journal Year: 2024, Volume and Issue: 935, P. 149076 - 149076

Published: Nov. 4, 2024

Language: Английский

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