PLANT PHYSIOLOGY,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 11, 2024
Abstract
Autophagy
is
a
membrane
trafficking
pathway
through
which
eukaryotic
cells
target
their
own
cytoplasmic
constituents
for
degradation
in
the
lytic
compartment.
Proper
biogenesis
of
autophagic
organelles
requires
conserved
set
autophagy-related
(ATG)
proteins
and
interacting
factors,
such
as
signalling
phospholipid
phosphatidylinositol
3-phosphate
(PI3P)
coat
complex
II
(COPII).
The
COPII
machinery,
was
originally
identified
involved
formation
vesicles
budding
from
endoplasmic
reticulum,
contributes
to
initiation
yeast,
metazoan,
plant
cells;
however,
exact
mechanisms
remain
elusive.
Recent
studies
using
model
species
Arabidopsis
thaliana
have
revealed
that
plant-specific
PI3P
effectors
are
autophagy.
effector
FYVE2
interacts
with
ATG18
components,
indicating
an
additional
role
machinery
later
stages
autophagosome
biogenesis.
In
this
Update,
we
examined
recent
research
on
proposed
working
models
functions
autophagy,
including
its
potential
roles
stabilizing
curvature
sealing
phagophore.
Journal of Experimental Botany,
Journal Year:
2023,
Volume and Issue:
75(5), P. 1234 - 1251
Published: Nov. 17, 2023
Abstract
Autophagy
is
an
evolutionarily
conserved
eukaryotic
intracellular
degradation
process.
Although
the
molecular
mechanisms
of
plant
autophagy
share
similarities
with
those
in
yeast
and
mammals,
certain
unique
have
been
identified.
Recent
studies
highlighted
importance
during
vegetative
growth
stages
as
well
plant-specific
developmental
processes,
such
seed
development,
germination,
flowering,
somatic
reprogramming.
enables
plants
to
adapt
manage
severe
environmental
conditions,
nutrient
starvation,
high-intensity
light
stress,
heat
leading
remodeling
physiological
changes
response
stress.
In
past,
research
lagged
behind
similar
mammals;
however,
recent
advances
greatly
expanded
our
understanding
functions.
This
review
summarizes
current
knowledge
latest
findings
on
roles
objective
improving
this
vital
process
plants.
The Plant Cell,
Journal Year:
2024,
Volume and Issue:
36(9), P. 3036 - 3056
Published: April 24, 2024
Plants
continuously
remodel
and
degrade
their
organelles
due
to
damage
from
metabolic
activities
environmental
stressors,
as
well
an
integral
part
of
cell
differentiation
programs.
Whereas
certain
use
local
hydrolytic
enzymes
for
limited
remodeling,
most
the
pathways
that
control
partial
or
complete
dismantling
rely
on
vacuolar
degradation.
Specifically,
selective
autophagic
play
a
crucial
role
in
recognizing
sorting
plant
organelle
cargo
clearance,
especially
under
cellular
stress
conditions
induced
by
factors
like
heat,
drought,
damaging
light.
In
these
short
reviews,
we
discuss
mechanisms
degradation
chloroplasts,
mitochondria,
endoplasmic
reticulum,
Golgi,
peroxisomes,
with
emphasis
autophagy,
recently
discovered
autophagy
receptors
organelles,
crosstalk
other
catabolic
pathways.
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 25, 2025
Abstract
Chloroplasts
are
major
photosynthetic
and
protein-containing
organelles
in
green
plants
algae.
Unwanted
chloroplast
proteins
entire
chloroplasts
cleared
through
various
degradation
pathways
including
autophagy.
Nevertheless,
canonical
chlorophagy
receptors
remain
unidentified,
whether
to
what
extent
can
be
enhanced
benefect
the
unknown.
Here
we
designed
validated
a
synthetic
autophagy
receptor
using
biochemical,
genetical,
imaging
approaches.
This
receptor,
LIR-SNT-BFP,
was
constructed
by
fusing
fragment
containing
LC3-interacting
region
(LIR)
of
selective
NBR1
N-terminal
amphipathic
α-helix
outer
envelope
protein
SFR2.
The
fusion
LIR-SNT-BFP
coated
attracted
ATG8a
planta
.
Upon
induction,
elicited
vacuole-mediated
microautophagy
independent
ATG8
conjugation
machinery
ATG5
or
ATG7.
Meanwhile,
it
induced
division;
however
PDV2.
Notably,
moderate
improves
rosette
growth,
but
excessive
levels
detrimental.
Furthermore,
partially
protects
against
herbicide-induced
leaf
chlorosis.
study
demonstrates
controlled
receptor.
The Plant Cell,
Journal Year:
2024,
Volume and Issue:
36(9), P. 3009 - 3024
Published: March 27, 2024
Autophagy
is
one
of
the
major
highly
inducible
degradation
processes
in
response
to
plant
developmental
and
environmental
signals.
In
different
stimuli,
cellular
materials,
including
proteins
organelles,
can
be
sequestered
into
a
double
membrane
autophagosome
structure
either
selectively
or
nonselectively.
The
formation
an
as
well
its
delivery
vacuole
involves
complex
dynamic
processes.
identification
characterization
conserved
autophagy-related
(ATG)
their
related
regulators
have
greatly
advanced
our
understanding
molecular
mechanism
underlying
biogenesis
function
cells.
Autophagosome
tightly
regulated
by
coordination
multiple
ATG
non-ATG
selective
cargo
recruitment.
This
review
updates
current
knowledge
biogenesis,
with
special
emphasis
on
core
machinery
that
drives
autophagosome-organelle
interactions
under
abiotic
stress
conditions.
The Plant Cell,
Journal Year:
2024,
Volume and Issue:
36(5), P. 1312 - 1333
Published: Jan. 16, 2024
Abstract
We
are
entering
an
exciting
century
in
the
study
of
plant
organelles
endomembrane
system.
Over
past
century,
especially
within
50
years,
tremendous
advancements
have
been
made
complex
cell
to
generate
a
much
clearer
and
informative
picture
organelles,
including
molecular/morphological
features,
dynamic/spatial
behavior,
physiological
functions.
Importantly,
all
these
discoveries
achievements
identification
characterization
system
would
not
possible
without:
(1)
innovations
timely
applications
various
state-of-art
biology
tools
technologies
for
organelle
research;
(2)
continuous
efforts
developing
characterizing
new
markers
by
community;
(3)
landmark
studies
on
elusive
organelles.
While
molecular
aspects
results
individual
extensively
reviewed,
development
techniques
research
is
less
appreciated.
As
one
ASPB
Centennial
Reviews
“organelle
biology,”
here
we
aim
take
journey
across
plants
highlighting
important
(or
technologies)
key
scientists
that
contributed
visualize
then
highlight
leading
systems.
