RNA Metabolism and the Role of Small RNAs in Regulating Multiple Aspects of RNA Metabolism DOI Creative Commons
Pranav Dawar,

Indra Adhikari,

Swarupa Nanda Mandal

et al.

Non-Coding RNA, Journal Year: 2024, Volume and Issue: 11(1), P. 1 - 1

Published: Dec. 24, 2024

RNA metabolism is focused on molecules and encompasses all the crucial processes an molecule may or will undergo throughout its life cycle. It essential cellular process that allows cells to function effectively. The transcriptomic landscape of a cell shaped by such as biosynthesis, maturation (RNA processing, folding, modification), intra- inter-cellular transport, transcriptional post-transcriptional regulation, modification, catabolic decay, retrograde signaling, which are interconnected for homeostasis. In eukaryotes, sRNAs, typically 20-31 nucleotides in length, class ncRNAs found nodes various gene regulatory networks. sRNAs known play significant roles regulating population at transcriptional, post-transcriptional, translational levels. Along with miRNAs, siRNAs, piRNAs, new categories ncRNAs, i.e., lncRNAs circRNAs, also contribute regulation eukaryotes. plants, genetic screens have demonstrated sRNA biogenesis mutants, well pathway exhibit similar growth development defects, misregulated primary secondary metabolism, impaired stress response. addition, both "products" "regulators" broad networks; networks involving form autoregulatory loops affect expression respective target. This review examines aspects pathways plants. explores potential conservation these across different kingdoms, particularly plants animals. Additionally, highlights how homeostasis directly impacts adaptive responses environmental changes developmental

Language: Английский

MiPEPs and cPEPs as tools to monitor plant gene expression and develop alternative strategies in agriculture DOI
Patrice Thuleau, Mélanie Ormancey, Serge Plaza

et al.

Journal of Experimental Botany, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 17, 2024

Abstract In order to develop a sustainable agriculture respecting the environment and reduce chemical inputs, new strategy has emerged in recent years, based on use of products targeting plant natural defense growth mechanisms. this context, few years ago we demonstrated existence plants regulatory peptides called miPEPs for ‘microRNA-encoded peptides’. miRNAs are small RNAs that down-regulate expression numerous genes eukaryotes. increase amount their cognate miRNA, resulting an even greater decrease targeted by these miRNAs. Thus, application artificial miPEP causes phenotype associated with change corresponding miRNA. More recently also identified peptides, namely cPEPs ‘complementary peptides’, capable enhancing activity given protein, independently any transcriptional activity. Moreover, as miPEPs, external makes it possible regulate phenotypes proteins. This review highlights most advances potential agronomy improve development stress tolerance.

Language: Английский

Citations

0
RNA Metabolism and the Role of Small RNAs in Regulating Multiple Aspects of RNA Metabolism DOI Creative Commons
Pranav Dawar,

Indra Adhikari,

Swarupa Nanda Mandal

et al.

Non-Coding RNA, Journal Year: 2024, Volume and Issue: 11(1), P. 1 - 1

Published: Dec. 24, 2024

RNA metabolism is focused on molecules and encompasses all the crucial processes an molecule may or will undergo throughout its life cycle. It essential cellular process that allows cells to function effectively. The transcriptomic landscape of a cell shaped by such as biosynthesis, maturation (RNA processing, folding, modification), intra- inter-cellular transport, transcriptional post-transcriptional regulation, modification, catabolic decay, retrograde signaling, which are interconnected for homeostasis. In eukaryotes, sRNAs, typically 20-31 nucleotides in length, class ncRNAs found nodes various gene regulatory networks. sRNAs known play significant roles regulating population at transcriptional, post-transcriptional, translational levels. Along with miRNAs, siRNAs, piRNAs, new categories ncRNAs, i.e., lncRNAs circRNAs, also contribute regulation eukaryotes. plants, genetic screens have demonstrated sRNA biogenesis mutants, well pathway exhibit similar growth development defects, misregulated primary secondary metabolism, impaired stress response. addition, both "products" "regulators" broad networks; networks involving form autoregulatory loops affect expression respective target. This review examines aspects pathways plants. explores potential conservation these across different kingdoms, particularly plants animals. Additionally, highlights how homeostasis directly impacts adaptive responses environmental changes developmental

Language: Английский

Citations

0