Predicting susceptibility to COVID-19 infection in patients on maintenance hemodialysis by cross-coupling soluble ACE2 concentration with lymphocyte count: an algorithmic approach DOI Creative Commons

Shuang Yuan,

Fulei Meng, Shuai Zhou

et al.

Frontiers in Medicine, Journal Year: 2024, Volume and Issue: 11

Published: Oct. 30, 2024

Patients on maintenance hemodialysis (MHD) were more vulnerable to and had a higher mortality during the COVID-19 pandemic. As angiotensin converting enzyme 2 (ACE2) transmembrane protease serine S1 member (TMPRSS2) played crucial roles in viral entry into human host cells, we therefore investigated MHD patients whether their plasma levels associated with susceptibility COVID-19.

Language: Английский

Effectiveness of non-pharmaceutical interventions as implemented in the UK during the COVID-19 pandemic: a rapid review DOI Creative Commons
Thulani Ashcroft, Emilie McSwiggan, Eldad Agyei‐Manu

et al.

Journal of Public Health, Journal Year: 2025, Volume and Issue: unknown

Published: March 4, 2025

Although non-pharmaceutical inventions (NPIs) were used globally to control the spread of COVID-19, their effectiveness remains uncertain. We aimed assess evidence on NPIs as implemented in UK, allow public health bodies prepare for future pandemics. rapid systematic methods (search date: January 2024) identify, critically appraise and synthesize interventional, observational modelling studies reporting NPI UK. Eighty-five modelling, nine three interventional included. Modelling had multiple quality issues; six 12 non-modelling high quality. The best available was test release strategies case contacts (moderate certainty), which suggestive a protective effect. school-related universal lockdown also effect, this considered low certainty. Evidence certainty remaining very or inconclusive. validity reliability UK during COVID-19 pandemic is weak. To improve generation support decision-making pandemics other emergencies, it essential build evaluation into design interventions.

Language: Английский

Citations

0

Assessing the effectiveness of non-pharmaceutical interventions in the SARS-CoV-2 pandemic: results of a natural experiment regarding Baden-Württemberg (Germany) and Switzerland in the second infection wave DOI
Thomas Wieland

Journal of Public Health, Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 28, 2024

Language: Английский

Citations

0

The public's considerations about implementing non-pharmaceutical interventions to manage a novel COVID-19 epidemic DOI Creative Commons
Sophie Kemper, Marion de Vries, Esther de Weger

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(9), P. e30390 - e30390

Published: April 26, 2024

In the future, new variants of SARS-CoV-2 virus might emerge and cause outbreaks.If this occurs, implementation non-pharmaceutical interventions (NPIs) can be reconsidered.Consideration potential benefits harms implementing NPIs, ultimately deciding about is currently mainly executed by experts governments.However, general literature on public engagement suggests that integrating perspectives into decision-making enhance quality decisions foster greater understanding them.In study, a deliberative mini-public was conducted to integrate perspective.The aim elicit considerations regarding asking diverse group citizens participate as decision-makers convene, learn deliberate during hypothetical outbreak variant.Participants emphasized importance early outbreak, prevent exceeding healthcare capacity, long-term mental health issues, educational deficits, bankruptcies.Additionally, participants stressed taking support account, shared ideas maintaining support.Furthermore, wanted give personal responsibility freedom in making their own assessment adherence how much risk infection they would willing accept.Participants also expressed need for government adopt learning attitude towards improvements pandemic response, generate more focus strategies.The minipublic, revealed reflected values needs.These helpful better aligning epidemic management policies with perspectives.Regarding mini-public, uncertainties remain design impact bigger scale.

Language: Английский

Citations

0

Voices of the Publics DOI Creative Commons
Sophie Kemper

Published: May 24, 2024

In decision-making about epidemic management, experts and policymakers in governmental institutions face the challenge of balancing numerous values, needs interest. These decisions are complex, have to be made within a context uncertainty, public unrest limited time. Despite potential value engagement, perspectives publics limitedly integrated management. Publics possess unique experiences, concerns, ideas that can aid complex trade-offs at certain times epidemics. Furthermore, engaging enhance their understanding processes, possibly even garner support for these trust institutions. Up until now, example supported response activities management such as surveillance, improvement communication campaigns or execution restriction measures. Yet, structural integration experiences into development strategies has not been realized. This raises uncertainties feasibility methodology incorporating engagement The primary objective this thesis was explore whether how using COVID-19 case.

Language: Английский

Citations

0

Predicting susceptibility to COVID-19 infection in patients on maintenance hemodialysis by cross-coupling soluble ACE2 concentration with lymphocyte count: an algorithmic approach DOI Creative Commons

Shuang Yuan,

Fulei Meng, Shuai Zhou

et al.

Frontiers in Medicine, Journal Year: 2024, Volume and Issue: 11

Published: Oct. 30, 2024

Patients on maintenance hemodialysis (MHD) were more vulnerable to and had a higher mortality during the COVID-19 pandemic. As angiotensin converting enzyme 2 (ACE2) transmembrane protease serine S1 member (TMPRSS2) played crucial roles in viral entry into human host cells, we therefore investigated MHD patients whether their plasma levels associated with susceptibility COVID-19.

Language: Английский

Citations

0