Disorganized communication and social dysfunction in schizophrenia: Emerging concepts and methods

Published: July 19, 2023

Purpose of review: In this review, we embrace the emerging field second-person neuroscience to address disorganization in schizophrenia. We argue that focus interest for is interpersonal space where shared mental processes (‘social mind’) occur based on bio-behavioural synchrony between two (or more) interacting people. lay out several measures can capture component parts process. particular, highlight real-time imaging technology hyperscanning enables multi-person analysis naturalistic social interaction. illustrate how these be used empirical studies by posing as a problem processing. Recent findings: Traditionally, disorganized speech and behaviour have been studied product hidden cognitive (‘private mind’). A dysfunction was attributed brain afflicted illness (‘brain-bound mechanisms’). But approach has contributed challenges measuring quantifying disorganization. Consequently, single-brain not provided satisfactory clarity or led effective treatments persistent schizophrenia.Summary: Social core feature This arises from interaction typifies profile affected individuals. outline employing concepts methods they addressed investigate mechanisms

Language: Английский

Overlap between individual differences in cognition and symptoms of schizophrenia

Published: Aug. 4, 2023

Background and Hypothesis. Neurocognitive impairment is a core feature of schizophrenia spectrum disorders (SSDs), the relationship between cognition symptoms in SSDs widely researched. The most well-replicated finding an association episodic memory negative symptoms; however, aspects that underpin this have yet to be specified.Study Design. We use iterative Constrained Principal Component Analysis (iCPCA) explore at level individual items while minimizing risk Type I errors. ICPCA was conducted on sample SSD patients early stages psychiatric treatment (n = 206) determine components overlapping with measured by Scale for Assessment Negative Symptoms (SANS) Positive (SAPS).Results. found verbal component associated from both SANS SAPS related disorganized impoverished communication, language thought (including positive formal disorder). In contrast, working motor system impoverishment. Both were social/clinical inattentiveness.Conclusions. allows finer-grained analysis illness responsible overlap symptoms, made possible analyzing instead symptom summary scores. These results suggest systems different symptomatology, implying distinct brain networks underpinning these relationships.

Language: Английский