Journal of American College Health,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 5
Published: Nov. 20, 2024
Insomnia,
anxiety,
and
depression
are
common
co-morbid
amongst
college
students.
The
mechanisms
by
which
trait
factors
like
intolerance
of
uncertainty
anxiety
sensitivity
connect
to
state
is
unclear,
but
insomnia
may
mediate
that
relationship.
College
students
(N
=
439)
were
recruited
from
national
local
sources.
Participants
completed
the
Sleep
Condition
Indicator
(SCI),
Depression,
Anxiety
Stress
Scale
(DASS),
Sensitivity
Index
(ASI),
Intolerance
Uncertainty
Scales
(IUS).
All
models
predicted
a
significant
amount
variability
in
(R2
between
0.24
0.32).
Mediation
analyses
revealed
relationship
anxiogenic
depressogenic
traits
significantly
mediated
insomnia.
Our
findings
support
role
expression
at-risk
Clinical
sleep
intervention,
either
reactive
or
prophylactic,
help
reduce
mental
health
burden
on
campus.
JMIR Mental Health,
Journal Year:
2021,
Volume and Issue:
8(4), P. e25847 - e25847
Published: March 10, 2021
An
estimated
1
in
5
adolescents
experience
a
mental
health
disorder
each
year;
yet
because
of
barriers
to
accessing
and
seeking
care,
most
remain
undiagnosed
untreated.
Furthermore,
the
early
emergence
psychopathology
contributes
lifelong
course
challenges
across
broad
set
functional
domains,
so
addressing
this
life
is
essential.
With
increasing
digital
connectivity,
including
low-
middle-income
countries,
technologies
are
considered
promising
for
among
young
people.
In
recent
years,
growing
number
interventions,
more
than
2
million
web-based
apps,
have
been
developed
address
range
issues.
Journal of Sleep Research,
Journal Year:
2022,
Volume and Issue:
31(4)
Published: April 22, 2022
Summary
Insomnia
disorder
comprises
symptoms
during
night
and
day
that
strongly
affect
quality
of
life
wellbeing.
Prolonged
sleep
latency,
difficulties
to
maintain
early
morning
wakening
characterize
complaints,
whereas
fatigue,
reduced
attention,
impaired
cognitive
functioning,
irritability,
anxiety
low
mood
are
key
daytime
impairments.
is
well
acknowledged
in
all
relevant
diagnostic
systems:
Diagnostic
Statistical
Manual
the
American
Psychiatric
Association,
5th
revision,
International
Classification
Sleep
Disorders,
3rd
version,
Diseases,
11th
revision.
as
a
chronic
condition
frequent
(up
10%
adult
population,
with
preponderance
females),
signifies
an
important
independent
risk
factor
for
physical
and,
especially,
mental
health.
diagnosis
primarily
rests
on
self‐report.
Objective
measures
like
actigraphy
or
polysomnography
not
(yet)
part
routine
canon,
but
play
role
research.
Disease
concepts
insomnia
range
from
cognitive‐behavioural
models
(epi‐)
genetics
psychoneurobiological
approaches.
The
latter
derived
knowledge
about
basic
sleep–wake
regulation
encompass
theories
rapid
eye
movement
instability/restless
sleep.
Cognitive‐behavioural
led
conceptualization
therapy
insomnia,
which
now
considered
first‐line
treatment
worldwide.
Future
research
strategies
will
include
combination
experimental
paradigms
neuroimaging
may
benefit
more
attention
dysfunctional
overnight
alleviation
distress
insomnia.
With
respect
therapy,
merits
widespread
implementation,
digital
assist
delivery
along
guidelines.
However,
given
still
considerable
proportion
patients
responding
insufficiently
fundamental
studies
highly
necessary
better
understand
brain
behavioural
mechanisms
underlying
Mediators
moderators
response/non‐response
associated
development
tailored
novel
interventions
also
require
investigation.
Recent
suggest
prove
add
significantly
preventive
strategy
combat
global
burden
disorders.
npj Digital Medicine,
Journal Year:
2025,
Volume and Issue:
8(1)
Published: March 12, 2025
Insomnia
impairs
daily
functioning
and
increases
health
risks.
Cognitive
behavioral
therapy
for
insomnia
(CBT-I)
is
effective
but
limited
by
cost
therapist
availability.
Fully
automated
digital
CBT-I
(FA
dCBT-I)
provides
an
accessible
alternative
without
involvement.
This
systematic
review
meta-analysis
evaluated
the
effectiveness
of
FA
dCBT-I
across
29
randomized
controlled
trials
(RCTs)
involving
9475
participants.
Compared
to
control
groups,
demonstrated
moderate
large
effects
on
severity.
Subgroup
analyses
indicated
that
had
a
significant
impact
when
contrasted
with
most
groups
was
less
than
therapist-assisted
CBT-I.
Meta-regression
revealed
group
type
moderated
outcomes,
whereas
completion
rate
did
not.
implies
treatment
adherence,
rather
merely
completing
intervention,
crucial
its
effectiveness.
study
supports
potential
as
promising
option
managing
underscores
hybrid
model
combining
support
more
beneficial.
Journal of Clinical Medicine,
Journal Year:
2025,
Volume and Issue:
14(7), P. 2265 - 2265
Published: March 26, 2025
Background/Objectives:
This
systematic
review
explores
the
integration
of
digital
and
AI-enhanced
cognitive
behavioral
therapy
(CBT)
for
insomnia,
focusing
on
underlying
neurocognitive
mechanisms
associated
clinical
outcomes.
Insomnia
significantly
impairs
functioning,
overall
health,
quality
life.
Although
traditional
CBT
has
demonstrated
efficacy,
its
scalability
ability
to
deliver
individualized
care
remain
limited.
Emerging
AI-driven
interventions-including
chatbots,
mobile
applications,
web-based
platforms-present
innovative
avenues
delivering
more
accessible
personalized
insomnia
treatments.
Methods:
Following
PRISMA
guidelines,
this
synthesized
findings
from
78
studies
published
between
2004
2024.
A
search
was
conducted
across
PubMed,
Scopus,
Web
Science,
PsycINFO.
Studies
were
included
based
predefined
criteria
prioritizing
randomized
controlled
trials
(RCTs)
high-quality
empirical
research
that
evaluated
AI-augmented
interventions
targeting
sleep
disorders,
particularly
insomnia.
Results:
The
suggest
improves
parameters,
patient
adherence,
satisfaction,
personalization
in
alignment
with
individual
profiles.
Moreover,
these
technologies
address
critical
limitations
conventional
CBT,
notably
those
related
access
scalability.
AI-based
tools
appear
especially
promising
optimizing
treatment
delivery
adapting
cognitive-behavioral
patterns.
Conclusions:
While
demonstrates
strong
potential
advancing
through
broader
accessibility,
several
challenges
persist.
These
include
uncertainties
surrounding
long-term
practical
implementation
barriers,
ethical
considerations.
Future
large-scale
longitudinal
is
necessary
confirm
sustained
benefits
AI-powered
Sleep Medicine,
Journal Year:
2022,
Volume and Issue:
101, P. 505 - 514
Published: Dec. 8, 2022
Insomnia,
depression,
and
anxiety
show
high
rates
of
comorbidity
functional
impairment.
Transdiagnostic
symptom
interactions
may
be
implicated
in
this
comorbidity.
This
network
analysis
sought
to
assess
how
symptoms
insomnia,
interact
individually
predict
impairment
across
several
domains
for
individuals
with
insomnia.
Baseline
psychometric
data
from
a
randomised
controlled
trial
were
analysed
(N
=
1711).
A
regularized
partial
correlation
was
estimated
the
data.
Centrality
(symptom
connectivity),
community
structure
clustering),
bridging
(inter-community
connectivity)
assessed.
The
replicability
model
assessed
via
confirmatory
analyses
holdout
sample.
Separately,
Shapley
values
determine
relative
importance
each
predicting
functioning
(i.e.,
psychological
wellbeing,
psychosocial
functioning,
physical
health
impairment).
most
connected
nodes
uncontrollable
worrying;
trouble
relaxing;
depressed
mood/hopelessness.
Five
communities
identified
relaxing
as
bridge
between
communities.
showed
good
fit
Low
energy
depressive
affect
(feelings
failure/guilt;
mood/hopelessness;
anhedonia)
key
predictors
multiple
Trouble
clinical
transdiagnostic
significance
context
In
terms
relate
it
clear
that,
while
low
feelings
failure/guilt
prominent
predictors,
range
are
associated
Consideration
both
useful
determining
targets
treatment.
is
secondary
an
original
trial.
Trial
registration
number:
ISRCTN60530898.
Registry
URL:
https://www.isrctn.com/ISRCTN60530898
Journal of Sleep Research,
Journal Year:
2023,
Volume and Issue:
32(6)
Published: Aug. 29, 2023
Summary
Cognitive
behavioural
therapy
(CBT)
is
the
recommended
first‐line
treatment
for
insomnia.
However,
guideline
care
very
seldom
available
and
most
patients
receive
no
treatment,
or
less
effective
second‐line
pharmacotherapy
sleep
hygiene,
neither
of
which
are
evidence‐based
chronic
The
primary
challenge
CBT
has
been
supply.
There
not
enough
therapists
to
meet
enormous
demand.
We
must
accelerate
clinician
training,
but
this
approach
can
never
be
sufficient,
even
with
abbreviated,
efficient
therapies.
Fortunately,
however,
landscape
also
changed
dramatically.
Fully‐automated
digital
(dCBT)
emerged
as
a
safe,
effective,
scalable
delivery
format.
dCBT
software
only,
so
it
disseminated
readily
widely
medication.
Moreover,
integrated
into
services.
Just
medications
delivered
through
health
professionals
systems,
approved
programmes
same.
an
ecosystem
psychologically‐based
should
necessitate
medical
prescription
model.
Our
proposed
stepped
framework,
comprises
both
population
clinical
service
initiatives,
enabling
universal
access
diverse
ways
in
may
(in‐person,
face‐to‐face,
using
telehealth,
group
therapy,
digitally)
operate
congruently
efficiently
optimise
people
at
all
levels
complexity
need.
With
safe
clinically
products
now
set
become
established
treatments,
clearly
differentiated
from
wellness
apps,
there
potential
rapidly
transform
insomnia
services
and,
first
time,
deliver
international
scale.
Journal of Sleep Research,
Journal Year:
2023,
Volume and Issue:
33(2)
Published: July 5, 2023
Stroke
is
frequently
accompanied
by
long-term
sleep
disruption.
We
therefore
aimed
to
assess
the
efficacy
of
digital
cognitive
behavioural
therapy
for
insomnia
improve
after
stroke.
A
parallel
group
randomised
controlled
trial
was
conducted
remotely
in
participant's
homes/online.
Randomisation
online
with
minimisation
between-group
differences
age
and
baseline
Sleep
Condition
Indicator-8
score.
In
total,
86
community-dwelling
stroke
survivors
consented,
whom
84
completed
assessments
(39
female,
mean
5.5
years
post-stroke,
59
old),
were
or
control
(sleep
hygiene
information).
Follow-up
at
post-intervention
(mean
75
days
baseline)
8
weeks
later.
The
primary
outcome
self-reported
symptoms,
as
per
(range
0-32,
lower
numbers
indicate
more
severe
insomnia,
reliable
change
7
points)
post-intervention.
There
significant
improvements
compared
(intention-to-treat,
n
=
48,
36,
5
imputed
datasets,
effect
p
≤
0.02,
Drug Safety,
Journal Year:
2024,
Volume and Issue:
47(11), P. 1061 - 1074
Published: July 11, 2024
The
growing
complexity
of
geriatric
pharmacotherapy
necessitates
effective
tools
for
mitigating
the
risks
associated
with
polypharmacy.
Screening
Tool
Older
Persons'
Potentially
Inappropriate
Prescriptions
(STOPP)/Screening
to
Alert
doctors
Right
Treatment
(START)
criteria
have
been
instrumental
in
optimizing
medication
management
among
older
adults.
Despite
their
large
adoption
improving
reduction
potentially
inappropriate
medications
(PIM)
and
patient
outcomes,
implementation
STOPP/START
faces
notable
challenges.
extensive
number
latest
version
time
constraints
primary
care
pose
practical
difficulties,
particularly
settings
a
high
patients.
This
paper
critically
evaluates
challenges
evolving
implications
applying
third
across
various
clinical
settings,
focusing
on
European
healthcare
context.
Utilizing
"Questions
&
Answers"
format,
it
examines
criteria's
discusses
relevant
suitability
potential
adaptations
address
diverse
needs
different
environments.
By
emphasizing
these
aspects,
this
aims
contribute
ongoing
discourse
enhancing
safety
efficacy
population,
promote
more
person-centred
an
aging
society.
SLEEP,
Journal Year:
2023,
Volume and Issue:
46(12)
Published: Oct. 31, 2023
Cognitive
behavioral
therapy
for
insomnia
is
now
recognized
as
the
front-line
treatment
chronic
insomnia,
yet
many
challenges
remain
in
improving
its
impact
and
reach.
This
manuscript
describes
our
perspective
on
some
of
these
challenges.
Based
literature
that
maladaptive
cognitions
predict
low
adherence
high
levels
cognitive-emotional
hyperarousal
may
be
associated
with
poor
outcomes,
we
propose
added
focus
cognitive
strategies
CBT-I.
Specifically,
broadening
range
traditional
strategies,
utilizing
acceptance-based
fuller
integration
broadened
into
CBT-I
throughout
course
treatment.
We
also
highlight
a
few
other
promising
emerging
approaches
to
enhance
These
include
involving
partners
promote
recommendations,
using
culturally
relevant
adaptations
increase
retention
patients
treatment,
timely
identification
barriers
engagement.
public
health
by
integrating
support
reduction
long-term
use
hypnotic
sleep
medications,
which
line
current
medical
guidelines.
advocate
case
conceptualization-based
approach
implementing
patient-centered
manner,
flexibly,
fidelity,
addressing
factors
above.
For
increasing
reach
CBT-I,
discuss
need
train
more
clinicians
ways
combine
therapist
digital
deliveries
highlighting
stepped
care
strategies.