Effect of myristic acid supplementation on triglyceride synthesis and related genes in the pectoral muscles of broiler chickens

Poultry Science, Journal Year: 2024, Volume and Issue: 103(10), P. 104038 - 104038

Published: June 27, 2024

Fatty acids (FAs) can serve as energy for poultry, maintain normal cell structure and function, support a healthy immune system. Although the addition of polyunsaturated fatty (PUFAs) to diet has been extensively studied reported, mechanism action saturated (SFAs) remains be elucidated. We investigated effect 0.04% dietary myristic acid (MA) on slaughter performance, lipid components, tissue FAs, transcriptome profile in chickens. The results showed that MA had no performance (body weight, carcass eviscerated pectoral muscle weight) (P > 0.05). Dietary enrichment increased < 0.001) triglycerides (TGs) 0.01) levels muscle. palmitic acid, linoleic (LA), arachidonic (AA), SFAs, monounsaturated (MUFAs), PUFAs were significantly higher supplementation group compared control group. However, there significant differences ratios PUFA/SFA n6/omega-3 (n3) between two groups. content was positively correlated with contents LA, linolenic (ALA), n3, n6, unsaturated (UFA). DHCR24, which is known involved steroid metabolism cholesterol biosynthesis pathways, found lower 0.05, log2(fold change) = -0.85). Five overlapping co-expressed genes identified at intersection differential expressed Weighted Gene Co‑expression Network Analysis-derived hub associated phenotype, namely BHLHE40, MSL1, PLAGL1, SRSF4, ENSGALG00000026875. For TG total 28 identified, including CHKA, KLF5, TGIF1, etc. Both sets included gene negative correlation TG. This study provides valuable information further understand regulation expression patterns by examines molecular level phenotypic changes induced MA.

Language: Английский

Predisposition factors and control strategies of avian pathogenic Escherichia coli in laying hens

Frontiers in Veterinary Science, Journal Year: 2024, Volume and Issue: 11

Published: Nov. 4, 2024

Shift in laying hens housing from conventional cage-based systems to alternatives has impacted their health and performance. Microorganisms colonize young chick the early stages of physiological immune development. These colonizing microbes originate parent environment. Escherichia coli is among normal gut bacteria however, some E. strains known as avian pathogenic (APEC), cause local or systemic infections (colibacillosis) responsible significant economic losses poultry industry. Potential APEC other microbiota are influenced by several factors such system, use feed additives (prebiotics, probiotics, symbiotic, others). This review will discuss status pullets layers immunity, health, predisposing colibacillosis. Dietary interventions colibacillosis mitigation strategies reviewed discussed. With development sequencing technologies antibiotics, future studies need understand complex associations between additives, rearing environment, selective pressure on microbiota, including , impacts hens.

Language: Английский