Protective effect of orientin on diabetic nephropathy in rat models of high-fat diet and streptozotocin-induced diabetes

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2025, Volume and Issue: unknown

Published: March 4, 2025

Language: Английский

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The state-of-the-art preparation, purification and biological activities of mannan oligosaccharides

Industrial Crops and Products, Journal Year: 2025, Volume and Issue: 225, P. 120594 - 120594

Published: Jan. 25, 2025

Language: Английский

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Effects of dietary levels of Bay laurel leaf extract conjugated with zinc nanoparticles on growth performance, carcass traits, and blood parameters in broilers

Annals of Animal Science, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 15, 2025

Abstract This study aimed to evaluate the effects of Bay laurel leaf extract conjugated with zinc nanoparticles (Zn-Nano-BLLE) as a growth enhancer and antibiotic alternative in broiler diets on performance, carcass characteristics, blood markers. In completely randomized design, 264 one-day-old Ross 308 chicks were divided into four experimental groups assess impact Zn-Nano-BLLE supplementation. Each group consisted six replicates, each containing 11 unsexed chicks. The treatments follows: control (basal diet) without any additives, three receiving at 1, 2, 3 cm³ Zn-Nano-BLLE/kg feed, respectively. Results indicated that supplementation 1 or cm³/kg feed led significant improvements live body weight gain. lowest intake conversion ratio observed broilers supplemented (30.94 1.14, respectively). However, highest dressing, carcass, heart percentages found group. Additionally, fed showed levels total protein, albumin, globulin, while also exhibiting cholesterol low-density lipoprotein (161.52 88.35, immunoglobulin G (IgG) elevated groups, although no noted M (IgM). Birds given 2 demonstrated superoxide dismutase activity (164 U/ml), had levels. conclusion, dietary inclusion Zn-Nano-BLLE, particularly cm³/kg, enhanced immunity, productivity, antioxidant status, indicates its effectiveness natural production.

Language: Английский

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Enhancing broiler growth, carcass quality, blood parameters and intestinal microbial load: the role of dietary garlic powder as a natural growth promoter

Annals of Animal Science, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 26, 2025

Abstract This study evaluated the effects of garlic powder (GP) as a natural growth promoter in broiler diets, replacing traditional antibiotics. Four experimental groups 264-day-old chicks (Ross 308) were established fully randomized design experiment. Each group had six replicates, each with eleven unsexed chicks. The treatments used follows: 1 st was basal diet without any additive (control group). 2 nd , 3 rd and 4 th (1 GP, GP GP) receving + 1, 2, g GP/kg feed, respectively. Results demonstrated that diets significantly improved feed conversion ratio (FCR), while led to greatest gains body weight, weight gain, intake. Blood analysis revealed elevated total protein, albumin, A/G ratios across all groups, alongside reduced creatinine ALT levels. notably increased HDL cholesterol (TC) LDL concentrations. Immunoglobulin Y (IgY) levels highest birds fed GP/kg, IgM peaking group. Additionally, enhanced superoxide dismutase (SOD) activity malondialdehyde (MDA) levels, marker oxidative stress. In contrast, control exhibited MDA lactic acid bacteria (LAB) bacterial count (TBC) are found However, E. coli . conclusion, incorporating into immune response, blood parameters, overall growth, gut counts optimal observed at GP/kg.

Language: Английский

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The potential effects of cranberry extract on indomethacin-induced gastric ulcer in rats

F1000Research, Journal Year: 2025, Volume and Issue: 14, P. 257 - 257

Published: March 4, 2025

Background Indomethacin (IND) belongs to nonsteroidal anti-inflammatory drugs (NSAIDs) prescribed for treatment of rheumatoid diseases and linked the development gastric ulcers in many people. Cranberry is a rich source polyphenols flavonoids, which have powerful antioxidant properties. Methods This study aimed evaluate activity cranberry aqueous extract on IND-induced albino rats. Twenty-four adult male rats were sequentially assigned four groups six each. The control group consumes distilled water (DW) orally 15 days. IND (induction) received single oral dosage (60 mg/kg) IND. omeprazole (OMP) got 60 mg/kg as dose then 20 mg/kg/day OMP was given subsequently 200 Rats euthanized day 16, tissues removed biochemical histopathological evaluations. Results considerably ameliorated severity ulcerations fixed histological deteriorations. Furthermore, IND-exposed treated with exhibited dramatically lower serum levels inflammatory biomarkers like TNF-α IL-6, but higher anti-oxidative SOD GPx. bioactive flavonoids content could possibly account its profound gastroprotective effects. properties be promising strategy ameliorating IND-aggravated gastrotoxicity.

Language: Английский

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Consequences of Dietary Olive Leaf Powder Supplementation on Growth Performance, Carcass Traits, Blood Biochemical Parameters and Gut Microbiota in Broilers

Poultry Science, Journal Year: 2025, Volume and Issue: unknown, P. 105087 - 105087

Published: March 1, 2025

This experiment examined the potential of olive leaf powder (OLP) as a natural growth enhancer in broiler feed and its influences on performance, carcass characteristics, blood parameters, intestinal bacterial count. A total 210 one-day-old Arbor Acres chicks were randomly allocated into three groups. The control group was given basal diet only, 2nd 3rd groups supplemented with 1 g OLP 2 OLP/kg diet, respectively. Each consisted seven replicates 10 unsexed each. experimental trial lasted for thirty-one days. Results showed that, OLP2 exhibited significant increase live body weight (LBW) at days 14 21 age, whereas OLP1 experienced considerable rise gain (BWG) between 29 31 age. Average daily intake (ADFI) considerably decreased during first 8-14 trial, but increased next 29-31 throughout entire duration (1-31 days). While, Feed conversion ratio (FCR) improved 15-31 trial. Carcass breast yields significantly supplementation, while abdominal fat content reduced. Blood analysis revealed enhances protein, albumin, globulin levels both groups, alanine transaminase (ALT), creatinine, cholesterol (TC), triglycerides (TG), very low-density lipoprotein (VLDL) Notably, immunity antioxidant markers improvement supplementation. Due to number beneficial bacteria such Lactobacillus rose all harmful (E. coli Clostridium) caecal samples declined. In conclusion, supplementation per kg demonstrated positive impact quality, lipid profile, immunity, status, raised contents chickens, making it promising promoter poultry production.

Language: Английский

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Enhancing production, reproduction, and health in laying quails through probiotic supplementation (Bacillus Toyonensis and Bifidobacterium Bifidum): effects on performance, physiological parameters, and gut microbiota

Annals of Animal Science, Journal Year: 2025, Volume and Issue: unknown

Published: April 8, 2025

Abstract The objectives of this investigation were to evaluate the influence dietary supplementation with different levels Bacillus toyonensis ATCC 55050 (BT), Bifidobacterium bifidum 29521 (BB), and a combination half dose BT BB on productive performance, carcass characteristics, physiological parameters, gut microbiota laying Japanese quails (Coturnix coturnix japonica). A total 144 quail chicks (56 days old, quail) assigned four experimental groups in fully randomized design experiment for 12 weeks. Twelve replicates, each consisting two female one male bird, created group. control group birds received corn-soybean basal diet from 56 140 trial. In contrast, receiving probiotics given same supplemented 0.1% or 0.05% plus (BT+BB). There was significant enhancement (P<0.05) performance traits during weeks age as result treatments both (BT+BB), except live body weight. results demonstrated various probiotic fertility (Fer) hatchability (Ha) percentages. BT+BB showed highest (98.57%) embryonic mortality (15.95%) compared other treatments. Also, digestive enzymes activity significantly enhanced by (BT+BB) treatments, besides, treatment higher all antioxidant traits. summary, addition their improved blood traits, decrease bacterial counts, coliform levels, fungi, cecal microflora.

Language: Английский

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Effects of dietary supplementation with Laurus nobilis extract on growth performance, carcass features, blood lipid profile, immunity, antioxidative status, digestive enzymes, and gut microbial load in growing New Zealand white rabbits

Tropical Animal Health and Production, Journal Year: 2025, Volume and Issue: 57(4)

Published: April 24, 2025

Language: Английский

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Impacts of dietary different levels of thyme leave powder as a natural growth promoter on growth performance, carcass characteristics, and blood indices of broilers

Poultry Science, Journal Year: 2024, Volume and Issue: 103(12), P. 104396 - 104396

Published: Oct. 10, 2024

The objective of the present study was to ascertain influence thyme leaf powder (TLP) on growth rate, carcass features, and blood indicators in broiler diets as a natural antioxidant antibiotic substitute. A fully randomized design experiment divided 264-day-old chicks (Ross 308) into 4 experimental groups. Six replicates each group, containing 11 unsexed chicks, were created. following therapies: control group without additive (basal diet); TLP1, TLP2 TLP3: basal diet + 1, 2 3 g leaves powder/kg diet, respectively. Results showed that TLP added at or g/kg feed significantly enhanced body weight gain (except for period from 16 30 d life), intake 1 15 conversion ratio throughout period. Furthermore, there significant decrease creatinine alanine aminotransferase (ALT) with different levels, particularly TLP/kg diet. Compared birds' included highest levels albumin total protein A/G (albumin/globulin) ratio. birds fed had lowest concentrations low-density lipoprotein (LDL) cholesterol (TC). Moreover, all treatment higher IgY than group. Nevertheless, including IgM levels. Additionally, superoxide dismutase activity (SOD) 1g minimum Notably, malondialdehyde (MDA) maximum meal TLP/kg. We may conclude using increases immunity, productivity, overall health, especially level

Language: Английский

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