Neonatal outcomes of maternal prenatal coronavirus infection DOI
İstemi Han Çelik, Atakan Tanaçan, Fuat Emre Canpolat

et al.

Pediatric Research, Journal Year: 2023, Volume and Issue: 95(2), P. 445 - 455

Published: Dec. 6, 2023

Language: Английский

Pregnancy and COVID-19: prevention, vaccination, therapy, and beyond DOI Creative Commons
Dilek Şahın, Atakan Tanaçan, Sophia Webster

et al.

TURKISH JOURNAL OF MEDICAL SCIENCES, Journal Year: 2021, Volume and Issue: 51(SI-1), P. 3312 - 3326

Published: Sept. 19, 2021

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has alarmed the world since its first emergence. As pregnancy is characterized significant changes in cardiovascular, respiratory, endocrine, and immunological systems, there are concerns on issues like course of pregnant women, safety medications, route delivery risk obstetric complications. The aim this review to summarize current literature management women during COVID-19 pandemic. Although more than 90% with recover without serious morbidity, rapid deterioration higher rates complications may be observed. vertical transmission not been clearly revealed yet. Decreasing number prenatal visits, shortening time allocated for examinations, active use telemedicine services, limiting persons healthcare settings, combining tests same visit, restricting visitors providing a safe environment facilities, strict hygiene control, personal protective equipment visits main strategies control spread according guidelines. new medication alternatives being proposed every day treatment COVID-19, our knowledge about most these drugs limited. Preliminary results promising administration SARS-CoV-2 vaccines population. Timing should decided based maternal health condition, accompanying gestational age. Cesarean performed indications. Breast feeding encouraged as long necessary precautions viral taken. In conclusion, an individualized approach provided multidisciplinary team achieve favorable outcomes.

Language: Английский

Citations

35

COVID-19 vaccine acceptance and coverage among pregnant persons in the United States DOI Creative Commons
Annette K. Regan, Ravneet Kaur,

Marcianna Nosek

et al.

Preventive Medicine Reports, Journal Year: 2022, Volume and Issue: 29, P. 101977 - 101977

Published: Sept. 7, 2022

Pregnant persons are at higher risk of severe COVID-19. Although vaccination is recommended, COVID-19 rates lower among pregnant compared to the non-pregnant population. We aimed evaluate acceptance any dose vaccine during pregnancy. A national online cross-sectional survey US adults who were between December 2020 and July 2021 was used measure behaviors, attitudes, beliefs. Post-stratification weighting ensure representativeness Marginal log-binomial models estimate adjusted prevalence ratios (aPR) acceptance, accounting for sociodemographic factors. Of 5,660 responded advertisements, 2,213 met eligibility criteria completed survey; 55.4% respondents received or planned receive prior pregnancy, 27.0% vaccinate after 8.8% unsure 8.7% had no plans vaccinate. Individuals more likely plan if they group prenatal care (aPR 1.57; 95% CI 1.40, 1.75), employed in a workplace with policy recommending 1.15; 1.06, 1.26), believed vaccines safe 2.86; 2.49, 3.29). recommended by their healthcare provider less commonly reported concerns about safety (35.5% vs 55.9%) accept 1.52; 1.31, 1.76). pregnancy not universal public health intervention will be needed continue increase coverage.

Language: Английский

Citations

24

The coronavirus disease 2019 infection in pregnancy and adverse pregnancy outcomes: a systematic review and meta-analysis DOI Creative Commons

Y. W. Jeong,

Min‐A Kim

Obstetrics & Gynecology Science, Journal Year: 2023, Volume and Issue: 66(4), P. 270 - 289

Published: May 17, 2023

The coronavirus disease 2019 (COVID-19) outbreak which started in December rapidly developed into a global health concern. Pregnant women are susceptible to respiratory infections and can experience adverse outcomes. This systematic review meta-analysis compared pregnancy outcomes according COVID-19 status. MEDLINE, EMBASE, Cochrane Library databases were searched for relevant articles published between 1, 2019, October 19, 2022. Main inclusion criterion was any population-based, cross-sectional, cohort, or case-control study that assessed with without laboratory-confirmed COVID-19. Sixty-nine studies including 1,606,543 pregnant (39,716 [2.4%] diagnosed COVID-19) retrieved. COVID-19-infected had higher risk of preterm birth (odds ratio [OR], 1.59; 95% confidence interval [CI], 1.42-1.78), preeclampsia (OR, 1.41; CI, 1.30-1.53), low weight 1.52; 1.30-1.79), cesarean delivery 1.20; 1.10-1.30), stillbirth 1.71; 1.39-2.10), fetal distress 2.49; 1.54-4.03), neonatal intensive care unit admission 2.33; 1.72-3.16), perinatal mortality 1.96; 1.15-3.34), maternal 6.15; 3.74-10.10). There no significant differences total miscarriage, premature rupture membranes, postpartum hemorrhage, cholestasis, chorioamnionitis infection. demonstrates infection during lead information could aid researchers clinicians preparing another pandemic caused by newly discovered viruses. findings this may assist evidence-based counseling help manage

Language: Английский

Citations

16

The impact of COVID-19 in pregnancy: Part I. Clinical presentations and untoward outcomes of pregnant women with COVID-19 DOI Creative Commons
Peng‐Hui Wang,

Wen-Ling Lee,

Szu‐Ting Yang

et al.

Journal of the Chinese Medical Association, Journal Year: 2021, Volume and Issue: 84(9), P. 813 - 820

Published: Aug. 5, 2021

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease 2019, COVID-19) is a pandemic with rapidly and widely disseminating to the world. Based on experiences about H1N1, Acute Respiratory Syndrome (SARS) Middle East (MERS) pandemics, pregnant women who are infected disproportionately more likely develop severe illness need hospitalizations, intensive care, finally die of diseases compared those nonpregnant counterparts or without infection. Although than one half COVID-19 asymptomatic, as well their symptoms frequently mild, this observation presents further challenge regarding service provision, prevention, management, in which may result overlooking risk during pregnancy. As predictable, despite much advance critical care recent decades, 2020 pandemic, really at higher progress illness; require hospitalization; such use mechanical ventilation extracorporeal membrane oxygenation (ECMO), most important, COVID-19. The magnitude extend newborn from resultant significantly increasing perinatal neonatal morbidity mortality rates. heightened untoward outcomes emphasizes an urgent national international recommendations guidelines optimize prevention management strategies for Active passive approved effective attempt be Understanding that vulnerable population essential improve novel pandemic. current review part I summarize up-to-date information impact laboratory-confirmed SARS-CoV-2 infection focus clinical presentations pregnancy these SARS-CoV-2.

Language: Английский

Citations

27

Mild COVID-19 Was Not Associated with Impaired IVF Outcomes or Early Pregnancy Loss in IVF Patients DOI Open Access

Yossef Kabalkin,

Yaakov Bentov,

Moran Gil

et al.

Journal of Clinical Medicine, Journal Year: 2022, Volume and Issue: 11(18), P. 5265 - 5265

Published: Sept. 6, 2022

Data collection regarding the effects of COVID-19 on reproduction is ongoing. This study examined effect IVF cycle parameters and early pregnancy outcomes. It included two arms: first compared non-exposed cycles to post-SARS-CoV-2 cycles. Sperm were also compared. The second, prospective arm outcomes among patients who contracted during those did not. None vaccinated against SARS-CoV-2. 60 treatment women with confirmed COVID-19, (either same patient before exposure or matched patients). not differ significantly between exposed groups, including number oocytes, endometrial thickness, fertilization rate top-quality embryos. In 11 cycles, male partner had recently recovered: sperm concentration was lower post-exposure: 6.27 million/mL vs. 16.5 pre-exposure (p = 0.008). 189 IVF-achieved pregnancies, loss hospital admissions groups. appears be unaffected by SARS-CoV-2 disease, despite a minor decline in recent recoverees.

Language: Английский

Citations

18

Reduced fetal movements and COVID-19 infection: a retrospective cohort study DOI Creative Commons
A Gentili, Irene Sterpu, Joanna Tingström

et al.

BMC Pregnancy and Childbirth, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 30, 2025

Abstract Background Fetal movements are an important indicator of fetal well-being; therefore, reduced (RFMs) can indicate compromise. RFM is associated with growth restriction (FGR) and intrauterine death (IUFD). Studies have implied that COVID-19 infection increases the risk adverse outcomes, such as preterm birth IUFD. It unclear how may aggravate these outcomes among women presenting RFM. The aims study were to (1) determine whether in increased 2020 compared 2019, year before pandemic, (2) evaluate maternal during pregnancy was a factor for comparison previously established factors seeking care Methods All who sought due delivered at Soder Hospital from 2019 included. composite constructed between but without COVID-19. Results did not increase A twofold found all primiparous vs. multiparous (98/788 [12.4%] vs 37/644 [9.8%], AOR = 2.5, 95% CI (1.6–3.7). Conclusion proportion first pandemic before. Composite marginally higher COVID-19-positive group COVID-19-negative group, it statistically significant.

Language: Английский

Citations

0

Impact of SARS-CoV-2 on pregnancy and neonatal outcomes: An open prospective study of pregnant women in Brazil DOI Creative Commons
Úrsula Trovato Gomez, Rossana Pulcineli Vieira Francisco, Fernanda Spadotto Baptista

et al.

Clinics, Journal Year: 2022, Volume and Issue: 77, P. 100073 - 100073

Published: Jan. 1, 2022

To determine the incidence and risk of adverse obstetric neonatal outcomes according to SARS-CoV-2 infection severity in pregnant women.Open prospective study women tested for by serological molecular assays during pregnancy or delivery two hospitals Sao Paulo, Brazil from April 12, 2020, February 28, 2021. Five groups were considered analysis: C0, negative COVID-19 results no symptoms; C1, positive results, C2, with mild C3, moderate C4, severe symptoms. The association between was determined using multivariate analysis.734 eligible enrolled as follows: C0 (n = 357), C1 127), C2 174), C3 37), C4 39). following associated COVID-19: oligohydramnios (adjusted Odds Ratio [aOR] 6.18; 95% CI 1.87‒20.39), fetal distress (aOR 4.01; Confidence Interval [CI] 1.84‒8.75), preterm birth 5.51; 1.47‒20.61), longer hospital stay 1.66; 1.36‒2.02), admission intensive care unit 19.36; CI, 5.86‒63.99). All maternal 6, 15.4%, p < 0.001) 5, 12.5%, deaths most 4, 9.8%, occurred group. Moderate 6.23; 1.93‒20.13) 3.60; 1.45‒9.27). Mild 3.77; 1.56‒9.07).Adverse symptomatic status, increased disease severity.

Language: Английский

Citations

15

The COVID-19 pandemic in Brazilian pregnant and postpartum women: results from the REBRACO prospective cohort study DOI Creative Commons
Renato T. Souza, José Guilherme Cecatti, Rodolfo C. Pacagnella

et al.

Scientific Reports, Journal Year: 2022, Volume and Issue: 12(1)

Published: July 11, 2022

Abstract Brazil presented a very high number of maternal deaths and evident delays in healthcare. We aimed at evaluating the characteristics SARS-CoV-2 infection associated outcomes obstetric population. conducted prospective cohort study 15 Brazilian centers including symptomatic pregnant or postpartum women with suspected COVID-19 from Feb/2020 to Feb/2021. Women were followed until end pregnancy. analyzed pregnancy confirmed SARS, determining unadjusted risk ratios. In total, 729 initially included. Among those investigated for COVID-19, 51.3% (n = 289) 48% 270) negative. Initially (before May 15th), only 52.9% cases tested it was period highest proportion ICU admission deaths. Non-white ethnicity (RR 1.78 [1.04–3.04]), primary schooling less 2.16 [1.21–3.87]), being overweight 4.34 [1.04–19.01]) obese 6.55 [1.57–27.37]), having public prenatal care [1.01–4.68]), planned pregnancies 2.09 [1.15–3.78]), onset 6.00 [1.37–26.26]), chronic hypertension 2.15 [1.37–4.10]), pre-existing diabetes 3.20 [1.37–7.46]), asthma 2.22 [1.14–4.34]), anaemia 3.15 [1.14–8.71]) higher SARS. The availability tests varied throughout pandemic study; beginning most challenging period, worse outcomes. Socially vulnerable, previously ill more likely present SARS related COVID-19.

Language: Английский

Citations

13

Impact of COVID-19 on Pregnancy Outcomes across Trimesters in the United States DOI Creative Commons

S.T. Virk,

Karthik Gangu, Adeel Nasrullah

et al.

Biomedicines, Journal Year: 2023, Volume and Issue: 11(11), P. 2886 - 2886

Published: Oct. 25, 2023

Current knowledge regarding the association between trimester-specific changes during pregnancy and COVID-19 infection is limited. We utilized National Inpatient Sample (NIS) database to investigate outcomes among hospitalized pregnant women diagnosed with COVID-19.Out of 3,447,771 identified, those exhibited higher in-hospital mortality rates in their third trimester compared without virus. Notably, mechanical ventilation, acute kidney injury, renal replacement therapy, perinatal complications (preeclampsia, HELLP syndrome, preterm birth) were significantly elevated across all trimesters for patients. was found be more prevalent low-income, Hispanic women.Our findings suggest that associated increased risk maternal complications, particularly trimester. Furthermore, we observed significant racial socioeconomic disparities both prevalence outcomes. These emphasize need equitable healthcare strategies improve care diverse socioeconomically marginalized groups, ultimately aiming reduce adverse COVID-19-associated fetal

Language: Английский

Citations

8

COVID-19 Lockdown Increased the Risk of Preterm Birth DOI Creative Commons
Ting-ting Lin, Chen Zhang, Lei Chen

et al.

Frontiers in Medicine, Journal Year: 2021, Volume and Issue: 8

Published: Sept. 27, 2021

Purpose: To estimate whether the city-specific lockdown in Shanghai induced by COVID-19 pandemic affected preterm birth rates among uninfected pregnant women different trimesters. Methods: The population-based retrospective cohort study was conducted International Peace Maternity and Child Health Hospital (IPMCH) Shanghai, China. Pregnant without received perinatal healthcare during (from January 24, 2020 to March 2020) non-lockdown 2019 2019) period giving a live infant at IPMCH were enrolled. 1:1 propensity score matching Inverse probability of treatment weighting used evaluate (<37 weeks), very (<34 with premature rupture membranes (PROM-PTB), spontaneous intact (S-PTB), medically (MI-PTB) between two groups. Results: 8,270 group, 9,815 group. second trimester had higher risk PTB than those [OR: 1.43 (CI 1.01-2.02), ARD: 1.7% 0.04-3.4%), p = 0.045]. Furthermore, third PROM-PTB 1.64 1.09-2.47), 0.9% 0.2-1.6%), 0.02]; no group differences found related VPTB, S-PTB or MI-PTB. Conclusion: In this China, we that there an increased for non-infected who their trimester.

Language: Английский

Citations

18