Drug and Alcohol Dependence, Journal Year: 2024, Volume and Issue: 267, P. 112546 - 112546
Published: Dec. 28, 2024
Language: Английский
JAMA Internal Medicine, Journal Year: 2024, Volume and Issue: 184(9), P. 1083 - 1083
Published: July 22, 2024
Many studies have evaluated whether in utero cannabis exposure is associated with fetal and neonatal outcomes, yet little known about prenatal use maternal health outcomes during pregnancy.
Language: Английский
Citations
14
Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)
Published: March 9, 2024
Abstract Prenatal cannabis use is associated with adverse offspring neurodevelopmental outcomes, however the underlying mechanisms are relatively unknown. We sought to determine impact of chronic delta-9-tetrahydrocannabinol (THC) exposure on fetal neurodevelopment in a rhesus macaque model using advanced imaging combined molecular and tissue studies. Animals were divided into two groups, control (n = 5) THC-exposed 5), which received daily THC edible pre-conception throughout pregnancy. Fetal T2-weighted MRI was performed at gestational days 85 (G85), G110, G135 G155 assess volumetric brain development. At G155, animals underwent cesarean delivery collection cerebrospinal fluid (CSF) for microRNA (miRNA) studies histologic analysis. significant age by sex interactions growth, differences histology suggestive dysregulation. Two extracellular vesicle associated-miRNAs identified CSF; pathway analysis suggests that these miRNAs dysregulated axonal guidance netrin signaling. This data indicative subtle changes consistent observed histological data, suggesting potential role miRNA regulation THC. Further needed whether findings correlate long-term health.
Language: Английский
Citations
5
Birth, Journal Year: 2024, Volume and Issue: 51(4), P. 867 - 877
Published: Oct. 11, 2024
ABSTRACT Introduction Legalization in many jurisdictions has increased the prevalence of cannabis use, including during pregnancy and lactation. Accordingly, clinicians providing perinatal infant care are increasingly required to counsel about this topic, even if they do not feel comfortable or prepared for conversation. The aim research was explore how prenatal pregnant lactating women interact with consumption. Methods Using qualitative description, we conducted semi‐structured interviews 75 individuals Canada: 23 who provide lactation care, 52 made consumption decisions and/or Data were analyzed using inductive content analysis. Results Three phases clinical encounter influenced decision‐making consumption: initiation a discussion cannabis, sense‐making, outcome encounter. Patients described similar ideals counseling lactation: open, patient‐centered conversation grounded an informed model benefits, risks, alternatives cannabis. While these values as reflecting real interactions, patients reported that their experience, actual interactions did live up ideals. Conclusion Clinicians people report desiring same things from interaction cannabis: sharing information, identification values, facilitation decision. Both groups endorse nonjudgemental approach explores reasons why patient is considering reflects against available evidence known be safe.
Language: Английский
Citations
3
Substance Use & Misuse, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 9
Published: Jan. 24, 2025
Objective To explore recently/currently pregnant people's experiences and views about cannabis use during pregnancy their associated support for policies that punish people who cannabis.
Language: Английский
Citations
0
NeoReviews, Journal Year: 2025, Volume and Issue: 26(4), P. e247 - e263
Published: April 1, 2025
Cannabis is the most commonly used federally illicit substance during pregnancy in United States, with an estimated prevalence of 3% to 30%. The American College Obstetricians and Gynecologists Academy Pediatrics discourage cannabis use breastfeeding due safety concerns for fetus infant. Despite these recommendations, nearly half active users continue pregnancy. In this review, we summarize pharmacology metabolism a focus on delta-9-tetrahydrocannabinol, psychoactive component plant, highlighting its significance quantifying exposure impact outcomes studies. We also provide concise review current evidence effects perinatal pregnancy, infant, childhood outcomes, acknowledging limitations evidence. Additionally, targeted counseling recommendations harm reduction strategies lactation considerations birthing parents who cannabis.
Language: Английский
Citations
0
Drug and Alcohol Dependence Reports, Journal Year: 2025, Volume and Issue: 15, P. 100334 - 100334
Published: April 19, 2025
Language: Английский
Citations
0
Frontiers in Global Women s Health, Journal Year: 2024, Volume and Issue: 5
Published: April 18, 2024
This study aimed to explore competing priorities when cannabis is used during pregnancy from the perspective of providers and Black Latina people. Maternal use increasingly common, but patients alike struggle navigate it.
Language: Английский
Citations
2
SSP Modern Law and Practice, Journal Year: 2023, Volume and Issue: 3(4), P. 1 - 14
Published: Dec. 14, 2023
In global medical practice, physicians have faced criminal charges such as manslaughter, reckless endangerment, or negligent homicide following fatalities of patients. A comprehensive and interdisciplinary study was carried out, involving forensic pharmaceutical, immunological, well legal expertise. This focused on the competencies healthcare facility professionals, guided by pharmaceutical law within framework interactions between doctors, patients, pharmacists, lawyers. It specifically addressed mistakes made in field gynecology. The research encompassed an analysis how leading countries worldwide handle errors. categorized common missteps, including hazardous surgical methods, infections from care, diagnostic inaccuracies, risky blood transfusions. practices related to gynecological errors were scrutinized. Furthermore, led proposition normative initiatives for amendments additions Article 140 Criminal Code Ukraine, aiming address these issues more effectively.
Language: Английский
Citations
5
Journal of Psychosomatic Obstetrics & Gynecology, Journal Year: 2024, Volume and Issue: 45(1)
Published: Feb. 24, 2024
The aim of this study is to determine factors associated with cannabis discontinuation, assess the impact mental health and addiction interventions on discontinuation during pregnancy investigate neonatal discontinuation. This a 10-year cohort in tertiary hospital Barcelona, Spain, including women self-reported use pregnancy. Main outcome was based biological sample testing. Secondary outcomes were intensive care unit (NICU) admission, preterm birth, birth weight bottle-feeding. When detected pregnancy, 32 out 81 (38.3%) discontinued vs. four 61 (6.6%) when at (p < .001). Multivariate binary logistic regression showed that null parity (OR: 6.95, p = .011), detection 5.35, .018) early referral for counseling cessation first trimester 25.46, .001) increased Risk <37 weeks (11.4% 30.8%) NICU admission (25.7% 54.2%) lower Early interventions, are predictors
Language: Английский
Citations
1
Addiction, Journal Year: 2024, Volume and Issue: 119(11), P. 1987 - 1997
Published: July 31, 2024
To estimate the strength of association between psychiatric disorders and substance use (SUD), cannabis disorder (CUD) during early pregnancy.
Language: Английский
Citations
1