Pregnancy and Infant Outcomes Following SARS-CoV-2 Infection in Pregnancy during Delta Variant Predominance – Surveillance for Emerging Threats to Pregnant People and Infants DOI Creative Commons
Emily Reeves, Varsha Neelam, Emily O’Malley Olsen

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: Sept. 28, 2023

Abstract Background : SARS-CoV-2 infection in pregnancy is associated with an increased risk of adverse birth outcomes, such as preterm birth, stillbirth, and maternal infant complications. Prior research suggests severe COVID-19 illness stillbirth pregnant people during the Delta variant predominance 2021; however, those studies did not assess timing pregnancy, few described vaccination status. Objective Using a large population-based cohort, this study compared outcomes demographic clinical characteristics prior to period. Study Design This retrospective cohort analysis included persons confirmed from six U.S. jurisdictions reporting Surveillance for Emerging Threats Pregnant People Infants Network (SET-NET). Data were collected through case reports polymerase chain reaction (PCR) positive linkages certificates, fetal death records, immunization records obtain We frequency spontaneous abortion (<20 weeksgestation), (≥20 weeks), (<37 small gestational age, term NICU admission between time periods pre-Delta predominance. determined by when variants constituted more than 50% sequences isolated according regional genomic surveillance data, defined (March 3, 2020-June 25, 2021) (June 26-December 2021). Adjusted prevalence ratios (aPR) estimated each outcome measure using Poisson regression adjusted continuous race/ethnicity, insurance status at delivery. Results Among 57,529 57,171 (99.4%) liveborn infants, 56 (0.1%) abortions, 302 (0.5%) stillbirths. Most unvaccinated infection, highest proportion (78.5%). Of infections who previously vaccinated, last was median 183 days. Compared pre-Delta, higher stillbirths (0.7% versus 0.4%, aPR 1.57, 95% CI: 1.15, 2.14) births (12.8%versus 11.9%, 1.14, 1.07, 1.21). The period lower (aPR 0.72 95%, 0.64, 0.79) pre-Delta. During period, third trimester first andsecond combined 1.42, 1.29,1.57). Conclusion In U.S.-based majority unvaccinated, frequencies among occurring earlier pregnancy. These findings confirm risks on specifically presence presentation.

Language: Английский

Pregnancy and infant outcomes following SARS-CoV-2 infection in pregnancy during delta variant predominance – Surveillance for Emerging Threats to Pregnant People and Infants DOI
Emily Reeves, Varsha Neelam, Jeffrey M. Carlson

et al.

American Journal of Obstetrics & Gynecology MFM, Journal Year: 2023, Volume and Issue: 6(2), P. 101265 - 101265

Published: Dec. 21, 2023

Language: Английский

Citations

6
Association between SARS-CoV-2 infection during pregnancy and gestational diabetes: a claims-based cohort study DOI Creative Commons
Oscar Rincón‐Guevara, Bailey Wallace, Lyudmyla Kompaniyets

et al.

Clinical Infectious Diseases, Journal Year: 2024, Volume and Issue: 79(6), P. 1386 - 1393

Published: Aug. 19, 2024

Abstract Introduction Coronavirus disease 2019 (COVID-19) may be associated with gestational diabetes mellitus (GDM); however, evidence is limited by sample sizes and lack of control groups. Methods To assess the GDM risk after COVID-19 in pregnancy, we constructed a retrospective cohort pregnancies ending March 2020–October 2022 using medical claims. People diagnosis claims from conception to 21 weeks (n = 57 675) were matched 1:2 those without during pregnancy 115 350) age range, start month, encounter year-month. (claim ≥23 weeks) relative difference overall, race ethnicity, variant period estimated log-binomial models. Results was higher among compared (adjusted ratio [aRR] 1.12; 95% confidence interval [CI], 1.08–1.15). significantly non-Hispanic White (aRR 1.08; CI, 1.04–1.14), Black 1.15; 1.07–1.24), Hispanic 1.17; 1.10–1.24) pre-Delta 1.11–1.24) Omicron 1.07; 1.02–1.13) periods, but neither differed Delta 1.10; 1.04–1.17). The adjusted 0%–2% for all Conclusions modestly claims-based data, especially earlier SARS-CoV-2 periods. Because these associations are based on studies employing systematic testing warranted.

Language: Английский

Citations

0
Impact of COVID-19 in pregnancy on maternal and perinatal outcomes during the Delta variant period: a comparison of the Delta and pre-delta time periods, 2020–2021 DOI Creative Commons

Cherrie Morris,

Harshit Doshi, William Liu

et al.

Maternal Health Neonatology and Perinatology, Journal Year: 2024, Volume and Issue: 10(1)

Published: Sept. 30, 2024

Language: Английский

Citations

0
Pregnancy and Infant Outcomes Following SARS-CoV-2 Infection in Pregnancy during Delta Variant Predominance – Surveillance for Emerging Threats to Pregnant People and Infants DOI Creative Commons
Emily Reeves, Varsha Neelam, Emily O’Malley Olsen

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: Sept. 28, 2023

Abstract Background : SARS-CoV-2 infection in pregnancy is associated with an increased risk of adverse birth outcomes, such as preterm birth, stillbirth, and maternal infant complications. Prior research suggests severe COVID-19 illness stillbirth pregnant people during the Delta variant predominance 2021; however, those studies did not assess timing pregnancy, few described vaccination status. Objective Using a large population-based cohort, this study compared outcomes demographic clinical characteristics prior to period. Study Design This retrospective cohort analysis included persons confirmed from six U.S. jurisdictions reporting Surveillance for Emerging Threats Pregnant People Infants Network (SET-NET). Data were collected through case reports polymerase chain reaction (PCR) positive linkages certificates, fetal death records, immunization records obtain We frequency spontaneous abortion (<20 weeksgestation), (≥20 weeks), (<37 small gestational age, term NICU admission between time periods pre-Delta predominance. determined by when variants constituted more than 50% sequences isolated according regional genomic surveillance data, defined (March 3, 2020-June 25, 2021) (June 26-December 2021). Adjusted prevalence ratios (aPR) estimated each outcome measure using Poisson regression adjusted continuous race/ethnicity, insurance status at delivery. Results Among 57,529 57,171 (99.4%) liveborn infants, 56 (0.1%) abortions, 302 (0.5%) stillbirths. Most unvaccinated infection, highest proportion (78.5%). Of infections who previously vaccinated, last was median 183 days. Compared pre-Delta, higher stillbirths (0.7% versus 0.4%, aPR 1.57, 95% CI: 1.15, 2.14) births (12.8%versus 11.9%, 1.14, 1.07, 1.21). The period lower (aPR 0.72 95%, 0.64, 0.79) pre-Delta. During period, third trimester first andsecond combined 1.42, 1.29,1.57). Conclusion In U.S.-based majority unvaccinated, frequencies among occurring earlier pregnancy. These findings confirm risks on specifically presence presentation.

Language: Английский

Citations

0