Controlled expression of avian migratory fattening influences innate immune responses DOI Open Access
Marcin Tobółka, Zuzanna Zielińska, Leonida Fusani

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: May 18, 2023

Abstract While immunity is frequently suppressed when birds engage in strenuous migratory flights, whether and how changes during the rapid accumulation of energy stores preparation for migration remains largely unknown. Here, we induced pre-migratory fattening through controlled daylight common quails Coturnix coturnix regularly assessed a marker constitutive innate (Leukocyte Coping Capacity or LCC) measures body composition (lean fat mass). LCC responses were highest mid-fattening phase lowest was completed. At mid-fattening, also found that kept higher proportion lean mass (i.e. accumulated less fat) had peaks. Our results indicate undergo immunological as they accumulate propose this could be due to competing trade-off processes between metabolic remodelling immune system function. Summary statement Immunity vital migrating new environments. It costly competivite other physiological processes. Here bring evidence on process birds.

Language: Английский

Endocrine and molecular regulation of seasonal avian immune function DOI
Sayantan Sur, Jyoti Tiwari, Shalie Malik

et al.

Philosophical Transactions of the Royal Society B Biological Sciences, Journal Year: 2025, Volume and Issue: 380(1918)

Published: Jan. 23, 2025

Birds have evolved seasonal adaptations in multiple aspects of the innate and adaptive immune systems. Seasonal immunological are crucial for survival harsh environmental conditions response to increased prevalence acute chronic diseases. Similar other vertebrates, birds exhibit remarkable plasticity cytokine production, chemotaxis, phagocytosis inflammation across year. In this review, we provide a comparative perspective on rhythms bird function. We describe advances our understanding annual changes cells responses challenges. Then, role glucocorticoids, sex steroids, thyroid hormones (THs) melatonin act as immunomodulators is described. then discuss impact major emerging disease, high pathogenicity avian influenza, one most critical diseases with significant implications poultry wild populations. The review identifies need enhance knowledge tissues birds, at molecular, cellular hormonal levels Moreover, there absence information sex-specific variation Understanding system dynamics will aid addressing negative impacts pathogenic diseases, minimize global economic losses conservation efforts.This article part Theo Murphy meeting issue 'Circadian infection immunity'.

Language: Английский

Citations

1
Recovery of constitutive immune function after migratory endurance flight in free-living birds DOI Open Access
Cas Eikenaar, Alessia Ostolani,

Sven Hessler

et al.

Biology Letters, Journal Year: 2023, Volume and Issue: 19(2)

Published: Feb. 1, 2023

Strenuous physical activity can negatively affect constitutive innate immune function (CIF), the always present first line of defence against pathogens. CIF is non-specific, and thus vital when encountering novel A lowered likely increases risk infection disease. Migratory birds engage in truly extreme during their endurance flights, however, little known about how they deal with negative impact this has on function. By collecting both between- within-individual data we show, for time, that free-flying migratory recover several parameters stopovers, which are stationary periods between flights. With this, provide an important piece puzzle migrating cope physiological challenges face biannual journeys. Furthermore, our study stresses importance stopovers beyond fuel accumulation.

Language: Английский

Citations

11
Seasonal patterns and processes of migration in a long-distance migratory bird: energy or time minimization? DOI Creative Commons
Anders Hedenström, Linus Hedh

Proceedings of the Royal Society B Biological Sciences, Journal Year: 2024, Volume and Issue: 291(2024)

Published: June 1, 2024

Optimal migration theory prescribes adaptive strategies of energy, time or mortality minimization. To test alternative hypotheses energy- and time-minimization we used multisensory data loggers that record time-resolved flight activity light for positioning by geolocation in a long-distance migratory shorebird, the little ringed plover,

Language: Английский

Citations

4
Condition‐dependent immune response in a migrating shorebird, the common snipe Gallinago gallinago DOI Creative Commons
Radosław Włodarczyk, Maciej Kamiński, Piotr Minias

et al.

Journal of Avian Biology, Journal Year: 2025, Volume and Issue: 2025(1)

Published: Jan. 1, 2025

Bird migration, as an energy‐demanding activity, is expected to generate allocation trade‐offs between important biological processes. For example, long‐distance migratory flights may require redirection of resources from immune response and promote temporal immunosuppression. Individuals in high body condition have the capacity cope with costs migration while maintaining adequate levels activity. Here, we investigated covariation two measures a short‐distance shorebird, common snipe Gallinago gallinago . We captured experimentally induced using phytohaemagglutinin (PHA) 148 snipes during autumn migration. found positive relationship PHA‐induced indices reflecting aerobic (total blood haemoglobin concentration) level accumulated energy reserves (size‐corrected mass). The results provided evidence for condition‐dependent migrating snipes, indicating that high‐quality individuals are capable sustaining suggest abundant food at stopover sites help rapidly replenish essential effective functioning system. It also seems likely maintenance function or its upregulation confer significant adaptive advantages under ecological conditions increased pathogenic exposure

Language: Английский

Citations

0
Shifts in sex-specific immune gene expression in a beetle with parental care DOI Creative Commons
Nikoletta Andrea Nagy, José O. Valdebenito,

Johanna Lévai-Kiss

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: March 29, 2025

Language: Английский

Citations

0
Sustained cross-species transmission of gammacoronavirus in wild birds reveled by viral characterization in China DOI

Dan-Shu Wang,

Yingying Zou, Qian Liu

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: April 18, 2025

Abstract Gammacoronavirus (γ-CoV) primarily infects poultry, wild birds, and marine mammals. The widespread distribution circulation of γ-CoV in the ecological environment may lead to sustained transmission economic loss. To better understand diversity we collect 482 wild-bird fecal samples from Yunnan, encompassing fourteen bird species. We detected twelve positive five species, with characterization complete genomes - HNU5-1, HNU5-2, HNU5-3, HNU6-1, HNU6-2-indicating that these represent two viral HNU5 strains were derived Black-headed gull ( Chroicocephalus ridibundus ), while HNU6 came Mallard Anas platyrhynchos both those recombinant. strain exhibited highest sequence identity (95.45%) a isolated Numenius phaeopus (GenBank accession: PP845452 ). Similarly, showed 95.18% nucleotide PP845437 ) . Taxonomic analysis confirmed HNU6s belong anatis HNU5s attributed new Cross-species revealed active host-switching events among γ-CoVs, indicating potential γ-CoVs mammals bird, inter-wild inter-poultry transmission. In summary, report birds outline cross-species γ-CoVs. Our findings link hosts across different natural environments provide insights for exploring

Language: Английский

Citations

0
Controlled expression of avian pre-migratory fattening influences indices of innate immunity DOI Creative Commons
Marcin Tobółka, Zuzanna Zielińska, Leonida Fusani

et al.

Biology Open, Journal Year: 2024, Volume and Issue: 13(1)

Published: Jan. 15, 2024

ABSTRACT While immunity is frequently dampened when birds engage in strenuous migratory flights, whether and how changes during the rapid accumulation of energy stores preparation for migration remains largely unknown. Here we induced pre-migratory fattening through controlled daylight common quails (Coturnix coturnix) regularly assessed three markers constitutive innate (leukocyte coping capacity or LCC, hemagglutination hemolysis titres) measures body composition (lean fat mass). All showed similar over process. LCC responses, titres, were on average higher mid-fattening phase compared to peak-fattening phase, values those observed prior start fattening. At mid-fattening, found that a larger mass (as % mass) had lower peak responses titres. Reversibly, at also kept proportion lean highest peaks. Our results indicate undergo immune indices (over 8 weeks) as they accumulate propose this could be due competing trade-off processes between metabolic remodelling system function.

Language: Английский

Citations

3
Low migratory connectivity and similar migratory strategies in a shorebird with contrasting wintering population trends in Europe and West Africa DOI Creative Commons
Teresa Catry, Edna Correia, Jorge S. Gutiérrez

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Feb. 28, 2024

Abstract Migratory shorebird populations are declining worldwide, showing an apparent inability to respond the interplaying challenges emerging along their flyways. Within East Atlantic Flyway, non-breeding show moderate strong declines in Sub-Saharan Africa, contrasting with stable or increasing trends Europe. Local factors insufficient explain opposite tendencies and, therefore, investigating migratory strategies and connectivity of these may help identifying drivers demography. We followed journeys 20 grey plovers ( Pluvialis squatarola ) from wintering grounds Guinea-Bissau (West Africa), Portugal France (Europe) using tracking devices. Grey Africa Europe were found share breeding at European Russia Western Siberia, revealing low Eastern population. All individuals a “skipping” strategy, flying mostly mid-distance bouts, unexpected large network stopover sites re-fuel usually for short periods. identified 66 different West African, Russian/Siberian coasts. birds stopped Wadden Sea both periods, highlighting importance this region risk potential bottleneck. Low similar shared by do not support population trends.

Language: Английский

Citations

2
Shifts in sex-specific immune gene expression in a beetle with parental care: a possible association with sex roles DOI
Nikoletta Andrea Nagy, José O. Valdebenito, Johanna Kiss

et al.

Authorea (Authorea), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 23, 2024

Males and females generally differ in resource investment strategies to maximise reproductive output, sometimes at the expense of important systemic processes such as self-maintenance immune activity. Here, we used wild Lethrus apterus, a sexually dimorphic beetle with parental care, investigate influence sex roles (e.g., offspring provisioning) on their sex-specific gene expression across pseudo-longitudinal sampling framework. By determining activation males five successive moments within active period, showed that varies substantially, alternating between male bias female period. However, when pooling all dates together, there was no overall difference number up-regulated genes sexes. We discuss potential our results highlight importance sequential schemes understand ecological dynamics wild.

Language: Английский

Citations

0
Effects of immune status on stopover departure decisions are subordinate to those of condition, cloud cover and tailwind in autumn‐migrating common blackbirds Turdus merula DOI Creative Commons
Tjomme van Mastrigt, Kevin D. Matson, Sander Lagerveld

et al.

Journal of Avian Biology, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 12, 2024

Migratory birds encounter a large variety of parasites and pathogens en route invest in immune defences to limit the risk fitness costs infection. Since both migration carry costs, individuals on tight budgets may face trade‐offs between migratory progress status. Many species alternate legs strenuous flight with stopovers during which refuel, rest, recover physiologically. Despite this, most time energy consumed are actually spent stopovers. As result, identifying what determines stopover duration is key understanding how balance investments migration. Yet, it unknown under conditions an individual's status affect through We explored whether at arrival affects by radio‐tagging blood‐sampling common blackbirds Turdus merula autumn Dutch island Vlieland. To measure status, we quantified levels bacterial killing ability, natural antibodies, complement, haptoglobin, as well heterophil–lymphocyte ratios. show that departures peaked periods low cloud cover strong tailwinds. While lean prolonged stopovers, only found weak tendency prolongation elevated haptoglobin levels. conclude effects minimum durations subordinate those condition, cover, tailwinds autumn‐migrating blackbirds. Hence, future studies link should take weather into account.

Language: Английский

Citations

0