Applied Mathematics and Computation, Journal Year: 2021, Volume and Issue: 412, P. 126595 - 126595
Published: Aug. 20, 2021
Language: Английский
Applied Mathematics and Computation, Journal Year: 2021, Volume and Issue: 412, P. 126595 - 126595
Published: Aug. 20, 2021
Language: Английский
Progress in Aerospace Sciences, Journal Year: 2014, Volume and Issue: 74, P. 131 - 151
Published: Dec. 24, 2014
Language: Английский
Citations
147Scientific Reports, Journal Year: 2017, Volume and Issue: 7(1)
Published: March 3, 2017
Nanometric biocompatible Metal-Organic Frameworks (nanoMOFs) are promising candidates for drug delivery. Up to now, most studies have targeted the intravenous route, related pain and severe complications; whereas nanoMOFs oral administration, a commonly used non-invasive simpler remains however unexplored. We propose here biofriendly preparation of suitable nanocarrier based on benchmarked mesoporous iron(III) trimesate nanoparticles coated with bioadhesive polysaccharide chitosan (CS). This method does not hamper textural/structural properties sorption/release abilities upon surface engineering. The interaction between CS has been characterized through combination high resolution soft X-ray absorption computing simulation, while positive impact coating colloidal chemical stability under simulated conditions is demonstrated. Finally, intestinal barrier bypass capability biocompatibility CS-coated nanoMOF assessed in vitro, leading an increased permeability respect non-coated material, maintaining optimal biocompatibility. In conclusion, preservation interesting physicochemical features their adapted progressive biodegradation, together improved bypass, make these nanocarrier.
Language: Английский
Citations
142Carbohydrate Polymers, Journal Year: 2020, Volume and Issue: 254, P. 117324 - 117324
Published: Nov. 15, 2020
Language: Английский
Citations
133Applied Mathematics and Computation, Journal Year: 2015, Volume and Issue: 270, P. 756 - 767
Published: Sept. 8, 2015
Language: Английский
Citations
129Nature Communications, Journal Year: 2019, Volume and Issue: 10(1)
Published: Feb. 15, 2019
Abstract Humans exhibit a remarkable capacity for cooperation among genetically unrelated individuals. Yet, human is neither universal, nor stable. Instead, often bounded to members of particular groups, and such groups endogenously form or break apart. Cooperation networks are parochial under constant reconfiguration. Here, we demonstrate how emerge as consequence simple reputation heuristics people may use when deciding cooperate defect. These heuristics, “a friend friend” “the enemy an enemy” further lead the dynamic formation fission cooperative accompanied by rise fall agents. The ability humans safeguard kin-independent through gossip be, accordingly, closely interlinked with group-bounded that reconfiguration, ultimately preventing global stable cooperation.
Language: Английский
Citations
121Coral reefs of the world, Journal Year: 2019, Volume and Issue: unknown, P. 801 - 828
Published: Jan. 1, 2019
Language: Английский
Citations
116Advanced Drug Delivery Reviews, Journal Year: 2017, Volume and Issue: 112, P. 88 - 100
Published: Feb. 1, 2017
Language: Английский
Citations
113International Journal of Information Management, Journal Year: 2019, Volume and Issue: 56, P. 102013 - 102013
Published: Oct. 10, 2019
Language: Английский
Citations
110Frontiers in Plant Science, Journal Year: 2015, Volume and Issue: 6
Published: Dec. 17, 2015
To survive winter, many perennial plants become endodormant, a state of suspended growth maintained even in favorable growing environments. understand vegetative bud endodormancy, we collected paradormant, and ecodormant axillary buds from Populus trees under natural conditions. Of 44,441 gene models analyzed using NimbleGen microarrays, found that 1,362 (3.1%) were differentially expressed among the three dormancy states, another 429 (1.0%) during only one two transitions (false discovery rate p-value < 0.05). all genes, 69% down-regulated paradormancy to which was expected given lower metabolic activity associated with endodormancy. Dormancy accompanied by changes multiple genes DNA methylation (via RNA-directed methylation) histone modifications Polycomb Repressive Complex 2), confirming extending knowledge chromatin modification as major features transitions. Among chromatin-associated similar SPT (SUPPRESSOR OF TY) strongly up-regulated Transcription factor sets atypically endodormancy include seems encode trihelix transcription proteins involved responses ethylene, cold, other abiotic stresses. These latter factors ETHYLENE INSENSITIVE 3 (EIN3), ETHYLENE-RESPONSIVE ELEMENT BINDING PROTEIN (EBP), RESPONSE FACTOR (ERF), ZINC FINGER 10 (ZAT10), ZAT12, WRKY DNA-binding domain proteins. Analyses phytohormone-associated suggest important auxin, brassinosteroids occur We weaker evidence for salicylic acid jasmonic acid, little gibberellins, abscisic cytokinin. identified 315 upstream sequence motifs eight patterns expression, including novel previously circadian clock photoperiod, dehydration, ABA. Analogies between regulation flowering roles SQUAMOSA-PROMOTER PROTEIN-LIKE (SPL), DORMANCY ASSOCIATED MADS-BOX (DAM), SUPPRESSOR OVEREXPRESSION CONSTANS 1 (SOC1).
Language: Английский
Citations
109Lecture notes in computer science, Journal Year: 2015, Volume and Issue: unknown, P. 63 - 80
Published: Jan. 1, 2015
Language: Английский
Citations
104