Bioelectronic osteosynthesis plate to monitor the fracture bone healing using electric capacitive variations

Journal of Orthopaedic Surgery and Research, Journal Year: 2025, Volume and Issue: 20(1)

Published: Jan. 29, 2025

Bone fractures represent a global public health issue. Over the past few decades, sustained increase in number of incidents and prevalent cases have been reported, as well years lived with disability. Current monitoring techniques predominantly rely on imaging methods, which can result subjective assessments, expose patients to unnecessary cumulative doses radiation. Besides, they are costly incapable providing continuous daily detection fracture healing stages. Technological advances still required design fixation systems ability minimize risk delayed nonunion conditions for timely medical intervention, such that preventive procedures be provided. This work proposes. An innovative bioelectronic osteosynthesis plate, minimally customized from device used clinical practice, was developed monitor bone-implant interface effectively detect progression bone Our technology includes network-architectured capacitive interdigitated system, Bluetooth module, an analog-to-digital converter, multiplexer, microcontroller, miniaturized battery. Both experimental tests biological tissues numerical simulations show strong evidence this implant is able: (i) four distinct stages, capacitance decreases throughout process; (ii) callus formation across multiple target regions. provides significant contribution technologies highly personalized sensing biointerfaces. supports faster healing, mainly non-union conditions.

Language: Английский

Impact of transforaminal lumbar interbody fusion on rod load: a comparative biomechanical analysis between a cadaveric instrumentation and simulated bone fusion

Medical Engineering & Physics, Journal Year: 2025, Volume and Issue: unknown, P. 104339 - 104339

Published: April 1, 2025

Language: Английский